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MOUSE:TFF3

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tff3 (synonyms: Itf)
Protein Name(s) Trefoil factor 3

Intestinal trefoil factor mITF

External Links
UniProt Q62395
EMBL U24222
U24220
U24221
D38410
AJ271004
BC011042
U46858
CCDS CCDS37544.1
PIR JC4147
RefSeq NP_035705.1
UniGene Mm.4641
ProteinModelPortal Q62395
SMR Q62395
STRING 10090.ENSMUSP00000024827
PaxDb Q62395
Ensembl ENSMUST00000024827
GeneID 21786
KEGG mmu:21786
UCSC uc008buk.2
CTD 7033
MGI MGI:104638
eggNOG NOG79314
GeneTree ENSGT00390000000115
HOGENOM HOG000121778
HOVERGEN HBG004364
InParanoid Q62395
OMA TSEQCNN
OrthoDB EOG70W3GT
PhylomeDB Q62395
TreeFam TF336092
NextBio 301136
PRO PR:Q62395
Proteomes UP000000589
Bgee Q62395
CleanEx MM_TFF3
Genevestigator Q62395
GO GO:0032579
GO:0070062
GO:0030141
GO:0043434
Gene3D 4.10.110.10
InterPro IPR000519
IPR017994
IPR017957
Pfam PF00088
PRINTS PR00680
SMART SM00018
SUPFAM SSF57492
PROSITE PS00025
PS51448

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010906

regulation of glucose metabolic process

PMID:24086476[1]

ECO:0000314

P

Figures 3,4, and 5 show how Tff3 regulates glucose metabolism by decreasing the amount of blood glucose and increases glucose tolerance in different types of mice.

complete
CACAO 8778

involved_in

GO:0010906

regulation of glucose metabolic process

PMID:24086476[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030277

maintenance of gastrointestinal epithelium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000352558
RGD:620707

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1306805
PANTHER:PTN001013697
RGD:620707

C

Seeded From UniProt

complete

part_of

GO:0030141

secretory granule

PMID:15645444[3]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:18941)
  • part_of:(CL:0000160)

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q07654

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q07654
ensembl:ENSP00000430690

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Xue, Y et al. (2013) Tff3, as a novel peptide, regulates hepatic glucose metabolism. PLoS ONE 8 e75240 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Park, YK et al. (2005) Gene expression profile analysis of mouse colon embryonic development. Genesis 41 1-12 PubMed GONUTS page