RAT:NEU1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Oxt (synonyms: Ot)
Protein Name(s)	Oxytocin-neurophysin 1 OT-NPI Oxytocin Ocytocin Neurophysin 1
External Links
UniProt	P01179
EMBL	K01701 M25649 X12792 X59496
PIR	A21183
RefSeq	NP_037128.1
UniGene	Rn.48915
ProteinModelPortal	P01179
SMR	P01179
STRING	10116.ENSRNOP00000028829
Ensembl	ENSRNOT00000028829
GeneID	25504
KEGG	rno:25504
UCSC	RGD:3238
CTD	5020
RGD	3238
eggNOG	NOG44533
GeneTree	ENSGT00390000004511
HOGENOM	HOG000113768
HOVERGEN	HBG004462
InParanoid	P01179
KO	K05243
OMA	DGCRTDP
OrthoDB	EOG7NW6C5
PhylomeDB	P01179
TreeFam	TF333018
Reactome	REACT_263111 REACT_263374
NextBio	606917
PMAP-CutDB	P01179
PRO	PR:P01179
Proteomes	UP000002494
Genevestigator	P01179
GO	GO:0005737 GO:0005615 GO:0030141 GO:0043195 GO:0005184 GO:0031855 GO:0042756 GO:0042755 GO:0007565 GO:0007625 GO:0007507 GO:0042538 GO:0007595 GO:0060179 GO:0002125 GO:0042711 GO:0007613 GO:0045776 GO:0060455 GO:0035811 GO:0007567 GO:0045777 GO:0007204 GO:0045925 GO:0060450 GO:0010701 GO:0045778 GO:0060406 GO:0032308 GO:0035815 GO:0051965 GO:0050806 GO:0070474 GO:0044058 GO:0002027 GO:0051930 GO:0014823 GO:0001975 GO:0051591 GO:0042220 GO:0051602 GO:0032355 GO:0045472 GO:0032094 GO:0051384 GO:0014070 GO:0043434 GO:0032570 GO:0034695 GO:0032526 GO:0048545 GO:0009744 GO:0030431 GO:0035176 GO:0042713
Gene3D	2.60.9.10
InterPro	IPR000981 IPR022423
PANTHER	PTHR11681
Pfam	PF00220 PF00184
PIRSF	PIRSF001815
PRINTS	PR00831
ProDom	PD001676
SMART	SM00003
SUPFAM	SSF49606
PROSITE	PS00264

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0120162	positive regulation of cold-induced thermogenesis	PMID:18071238^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P35454	P	Seeded From UniProt	complete
involved_in	GO:0043207	response to external biotic stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01175:PRO_0000020491	P	Seeded From UniProt	complete
involved_in	GO:0032094	response to food	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01175:PRO_0000020491	P	Seeded From UniProt	complete
involved_in	GO:0009612	response to mechanical stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01175:PRO_0000020491	P	Seeded From UniProt	complete
involved_in	GO:0043207	response to external biotic stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:F1SWA3	P	Seeded From UniProt	complete
involved_in	GO:0032094	response to food	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:F1SWA3	P	Seeded From UniProt	complete
involved_in	GO:0009612	response to mechanical stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:F1SWA3	P	Seeded From UniProt	complete
involved_in	GO:0070474	positive regulation of uterine smooth muscle contraction	PMID:19164477^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060455	negative regulation of gastric acid secretion	PMID:11764003^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060450	positive regulation of hindgut contraction	PMID:19258489^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060406	positive regulation of penile erection	PMID:18671741^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060179	male mating behavior	PMID:18655888^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051965	positive regulation of synapse assembly	PMID:16488155^[7]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051930	regulation of sensory perception of pain	PMID:17664006^[8]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051602	response to electrical stimulus	PMID:18823708^[9]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051591	response to cAMP	PMID:11168841^[10]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051384	response to glucocorticoid	PMID:17553493^[11]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0050806	positive regulation of synaptic transmission	PMID:17314286^[12]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048545	response to steroid hormone	PMID:12588901^[13]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045925	positive regulation of female receptivity	PMID:11264328^[14]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045778	positive regulation of ossification	PMID:18257653^[15]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045777	positive regulation of blood pressure	PMID:19120122^[16]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045776	negative regulation of blood pressure	PMID:18562099^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045472	response to ether	PMID:1943445^[18]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0044058	regulation of digestive system process	PMID:12690433^[19]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0043434	response to peptide hormone	PMID:19246538^[20]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0043195	terminal bouton	PMID:18987209^[21]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0042756	drinking behavior	PMID:15380376^[22]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042755	eating behavior	PMID:15380376^[22]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042713	sperm ejaculation	PMID:18552879^[23]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042711	maternal behavior	PMID:18513132^[24]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042538	hyperosmotic salinity response	PMID:18088359^[25]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042220	response to cocaine	PMID:18609307^[26]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0035815	positive regulation of renal sodium excretion	PMID:17559853^[27]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0035811	negative regulation of urine volume	PMID:18057218^[28]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	PMID:17540347^[29]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0034695	response to prostaglandin E	PMID:19017254^[30]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032570	response to progesterone	PMID:17280592^[31]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032526	response to retinoic acid	PMID:15316117^[32]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032355	response to estradiol	PMID:19258489^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032308	positive regulation of prostaglandin secretion	PMID:9575824^[33]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0032094	response to food	PMID:18832082^[34]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0031855	oxytocin receptor binding	PMID:19560475^[35]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0031855	oxytocin receptor binding	PMID:15821089^[36]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0030431	sleep	PMID:12832103^[37]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0030141	secretory granule	PMID:11456414^[38]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0014823	response to activity	PMID:16157794^[39]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	PMID:19248249^[40]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	PMID:12504828^[41]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010701	positive regulation of norepinephrine secretion	PMID:14656297^[42]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0009744	response to sucrose	PMID:19022308^[43]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007625	grooming behavior	PMID:17505467^[44]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007613	memory	PMID:18304743^[45]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007565	female pregnancy	PMID:18936075^[46]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:15316117^[32]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	PMID:10497238^[47]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:19017254^[30]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:18953097^[48]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0005184	neuropeptide hormone activity	PMID:19560475^[35]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0002125	maternal aggressive behavior	PMID:18655888^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0002027	regulation of heart rate	PMID:3668162^[49]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0001975	response to amphetamine	PMID:17383105^[50]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005185	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005184	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005184	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P	Seeded From UniProt	complete
involved_in	GO:0120162	positive regulation of cold-induced thermogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35454 ensembl:ENSMUSP00000028764	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35454 ensembl:ENSMUSP00000028764	C	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35454 ensembl:ENSMUSP00000028764	C	Seeded From UniProt	complete
enables	GO:0005185	neurohypophyseal hormone activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000981 InterPro:IPR022423 InterPro:IPR036387	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000981 InterPro:IPR022423 InterPro:IPR036387	C	Seeded From UniProt	complete
involved_in	GO:0007595	lactation	PMID:14624682^[51]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007567	parturition	PMID:14624682^[51]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0005184	neuropeptide hormone activity	PMID:15821089^[36]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0372	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Kasahara, Y et al. (2007) Impaired thermoregulatory ability of oxytocin-deficient mice during cold-exposure. Biosci. Biotechnol. Biochem. 71 3122-6 PubMed GONUTS page
↑ Magalhaes, JK et al. (2009) Oxytocin pretreatment decreases oxytocin-induced myometrial contractions in pregnant rats in a concentration-dependent but not time-dependent manner. Reprod Sci 16 501-8 PubMed GONUTS page
↑ Asad, M et al. (2001) Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. Life Sci. 70 17-24 PubMed GONUTS page
↑ ^4.0 ^4.1 Feng, M et al. (2009) Estradiol upregulates the expression of oxytocin receptor in colon in rats. Am. J. Physiol. Endocrinol. Metab. 296 E1059-66 PubMed GONUTS page
↑ Succu, S et al. (2008) Oxytocin induces penile erection when injected into the ventral tegmental area of male rats: role of nitric oxide and cyclic GMP. Eur. J. Neurosci. 28 813-21 PubMed GONUTS page
↑ ^6.0 ^6.1 Veenema, AH & Neumann, ID (2008) Central vasopressin and oxytocin release: regulation of complex social behaviours. Prog. Brain Res. 170 261-76 PubMed GONUTS page
↑ Theodosis, DT et al. (2006) Oxytocin and estrogen promote rapid formation of functional GABA synapses in the adult supraoptic nucleus. Mol. Cell. Neurosci. 31 785-94 PubMed GONUTS page
↑ Yang, J et al. (2007) Effect of oxytocin on acupuncture analgesia in the rat. Neuropeptides 41 285-92 PubMed GONUTS page
↑ Martínez-Lorenzana, G et al. (2008) PVN electrical stimulation prolongs withdrawal latencies and releases oxytocin in cerebrospinal fluid, plasma, and spinal cord tissue in intact and neuropathic rats. Pain 140 265-73 PubMed GONUTS page
↑ Song, Z et al. (2001) cAMP stimulation of vasopressin and oxytocin release and regulation of vasopressin mRNA stability: role of auto-facilitation. J. Neuroendocrinol. 13 158-65 PubMed GONUTS page
↑ Ruginsk, SG et al. (2007) Glucocorticoid modulation of neuronal activity and hormone secretion induced by blood volume expansion. Exp. Neurol. 206 192-200 PubMed GONUTS page
↑ Wang, YF & Hatton, GI (2007) Dominant role of betagamma subunits of G-proteins in oxytocin-evoked burst firing. J. Neurosci. 27 1902-12 PubMed GONUTS page
↑ Widmer, H et al. (2003) Neurosteroid regulation of oxytocin and vasopressin release from the rat supraoptic nucleus. J. Physiol. (Lond.) 548 233-44 PubMed GONUTS page
↑ Bale, TL et al. (2001) CNS region-specific oxytocin receptor expression: importance in regulation of anxiety and sex behavior. J. Neurosci. 21 2546-52 PubMed GONUTS page
↑ Elabd, SK et al. (2007) Possible neuroendocrine role for oxytocin in bone remodeling. Endocr Regul 41 131-41 PubMed GONUTS page
↑ Bakos, J et al. (2008) Phenylethanolamine N-methyltransferase gene expression in the heart and blood pressure response to oxytocin treatment in rats exposed to voluntary wheel running. Ann. N. Y. Acad. Sci. 1148 302-7 PubMed GONUTS page
↑ Petersson, M & Uvnäs-Moberg, K (2008) Postnatal oxytocin treatment of spontaneously hypertensive male rats decreases blood pressure and body weight in adulthood. Neurosci. Lett. 440 166-9 PubMed GONUTS page
↑ Zierer, R (1991) Impact of ether anesthesia on the hypophyseal content of oxytocin neurophysin I and II: a comparative study with ketamine in the rat. Life Sci. 49 1391-7 PubMed GONUTS page
↑ Wu, CL et al. (2003) Pharmacological effects of oxytocin on gastric emptying and intestinal transit of a non-nutritive liquid meal in female rats. Naunyn Schmiedebergs Arch. Pharmacol. 367 406-13 PubMed GONUTS page
↑ Zelena, D et al. (2009) Vasopressin administration into the paraventricular nucleus normalizes plasma oxytocin and corticosterone levels in Brattleboro rats. Endocrinology 150 2791-8 PubMed GONUTS page
↑ Peters, JH et al. (2008) Oxytocin enhances cranial visceral afferent synaptic transmission to the solitary tract nucleus. J. Neurosci. 28 11731-40 PubMed GONUTS page
↑ ^22.0 ^22.1 Verty, AN et al. (2004) Evidence for an interaction between CB1 cannabinoid and oxytocin receptors in food and water intake. Neuropharmacology 47 593-603 PubMed GONUTS page
↑ Gupta, J et al. (2008) Oxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors. Br. J. Pharmacol. 155 118-26 PubMed GONUTS page
↑ Figueira, RJ et al. (2008) Oxytocin receptor activity in the ventrocaudal periaqueductal gray modulates anxiety-related behavior in postpartum rats. Behav. Neurosci. 122 618-28 PubMed GONUTS page
↑ Yue, C et al. (2008) Differential kinetics of oxytocin and vasopressin heteronuclear RNA expression in the rat supraoptic nucleus in response to chronic salt loading in vivo. J. Neuroendocrinol. 20 227-32 PubMed GONUTS page
↑ McMurray, MS et al. (2008) Intergenerational effects of cocaine on maternal aggressive behavior and brain oxytocin in rat dams. Stress 11 398-410 PubMed GONUTS page
↑ Bernal, A et al. (2007) Oxytocin, water intake, and food sodium availability in male rats. Horm Behav 52 289-96 PubMed GONUTS page
↑ Li, C et al. (2008) Molecular mechanisms of antidiuretic effect of oxytocin. J. Am. Soc. Nephrol. 19 225-32 PubMed GONUTS page
↑ Lee, PR et al. (2007) Prenatal stress generates deficits in rat social behavior: Reversal by oxytocin. Brain Res. 1156 152-67 PubMed GONUTS page
↑ ^30.0 ^30.1 Sun, X et al. (2009) The effects of alprostadil on hypothalamic and amygdalar function and the central expression of oxytocin: a potential central role of alprostadil cream. J Sex Med 6 81-90 PubMed GONUTS page
↑ Ochedalski, T et al. (2007) Interaction between oestrogen and oxytocin on hypothalamic-pituitary-adrenal axis activity. J. Neuroendocrinol. 19 189-97 PubMed GONUTS page
↑ ^32.0 ^32.1 Jankowski, M et al. (2004) Oxytocin in cardiac ontogeny. Proc. Natl. Acad. Sci. U.S.A. 101 13074-9 PubMed GONUTS page
↑ Strakova, Z et al. (1998) ERK2 mediates oxytocin-stimulated PGE2 synthesis. Am. J. Physiol. 274 E634-41 PubMed GONUTS page
↑ Hindmarch, C et al. (2008) Microarray analysis of the transcriptome of the subfornical organ in the rat: regulation by fluid and food deprivation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 R1914-20 PubMed GONUTS page
↑ ^35.0 ^35.1 Lukas, M et al. (2010) Maternal separation interferes with developmental changes in brain vasopressin and oxytocin receptor binding in male rats. Neuropharmacology 58 78-87 PubMed GONUTS page
↑ ^36.0 ^36.1 Huber, D et al. (2005) Vasopressin and oxytocin excite distinct neuronal populations in the central amygdala. Science 308 245-8 PubMed GONUTS page
↑ Lancel, M et al. (2003) Intracerebral oxytocin modulates sleep-wake behaviour in male rats. Regul. Pept. 114 145-52 PubMed GONUTS page
↑ Morel, G et al. (2001) Intrauterine oxytocin system. Compartmental distribution of oxytocin and oxytocin receptors in rat endometrial epithelium. Cell Tissue Res. 304 377-82 PubMed GONUTS page
↑ Martins, AS et al. (2005) Hypertension and exercise training differentially affect oxytocin and oxytocin receptor expression in the brain. Hypertension 46 1004-9 PubMed GONUTS page
↑ Kumcu, EK et al. (2009) Differential effect of neocuproine, a copper(I) chelator, on contractile activity in isolated ovariectomized non-pregnant rat, pregnant rat and pregnant human uterus. Eur. J. Pharmacol. 605 158-63 PubMed GONUTS page
↑ Wang, D et al. (2003) Genistein supplementation stimulates the oxytocin system in the aorta of ovariectomized rats. Cardiovasc. Res. 57 186-94 PubMed GONUTS page
↑ Onaka, T et al. (2003) Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus. Eur. J. Neurosci. 18 3018-26 PubMed GONUTS page
↑ Olszewski, PK et al. (2009) Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY. Peptides 30 226-33 PubMed GONUTS page
↑ Marroni, SS et al. (2007) Neuroanatomical and cellular substrates of hypergrooming induced by microinjection of oxytocin in central nucleus of amygdala, an experimental model of compulsive behavior. Mol. Psychiatry 12 1103-17 PubMed GONUTS page
↑ Larrazolo-López, A et al. (2008) Vaginocervical stimulation enhances social recognition memory in rats via oxytocin release in the olfactory bulb. Neuroscience 152 585-93 PubMed GONUTS page
↑ Arthur, P et al. (2008) Relationship between gene expression and function of uterotonic systems in the rat during gestation, uterine activation and both term and preterm labour. J. Physiol. (Lond.) 586 6063-76 PubMed GONUTS page
↑ Hoare, S et al. (1999) The proximal portion of the COOH terminus of the oxytocin receptor is required for coupling to g(q), but not g(i). Independent mechanisms for elevating intracellular calcium concentrations from intracellular stores. J. Biol. Chem. 274 28682-9 PubMed GONUTS page
↑ Juszczak, M & Boczek-Leszczyk, E (2008) Oxytocin release from the rat neurohypophysis into the blood: effects of tachykinin NK-1 and NK-2 receptors agonists and antagonists. J. Physiol. Pharmacol. 59 553-62 PubMed GONUTS page
↑ Yashpal, K et al. (1987) Oxytocin administered intrathecally preferentially increases heart rate rather than arterial pressure in the rat. J. Auton. Nerv. Syst. 20 167-78 PubMed GONUTS page
↑ Thompson, MR et al. (2007) A role for oxytocin and 5-HT(1A) receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine ("ecstasy"). Neuroscience 146 509-14 PubMed GONUTS page
↑ ^51.0 ^51.1 Holmes, CL et al. (2003) Science review: Vasopressin and the cardiovascular system part 1--receptor physiology. Crit Care 7 427-34 PubMed GONUTS page

[PMID:18071238-1] Kasahara, Y et al. (2007) Impaired thermoregulatory ability of oxytocin-deficient mice during cold-exposure. Biosci. Biotechnol. Biochem. 71 3122-6 PubMed GONUTS page

[PMID:19164477-2] Magalhaes, JK et al. (2009) Oxytocin pretreatment decreases oxytocin-induced myometrial contractions in pregnant rats in a concentration-dependent but not time-dependent manner. Reprod Sci 16 501-8 PubMed GONUTS page

[PMID:11764003-3] Asad, M et al. (2001) Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. Life Sci. 70 17-24 PubMed GONUTS page

[PMID:19258489-4] 4.0 ^4.1 Feng, M et al. (2009) Estradiol upregulates the expression of oxytocin receptor in colon in rats. Am. J. Physiol. Endocrinol. Metab. 296 E1059-66 PubMed GONUTS page

[PMID:18671741-5] Succu, S et al. (2008) Oxytocin induces penile erection when injected into the ventral tegmental area of male rats: role of nitric oxide and cyclic GMP. Eur. J. Neurosci. 28 813-21 PubMed GONUTS page

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