RAT:DRD1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Drd1 (synonyms: Drd1a)
Protein Name(s)	D(1A) dopamine receptor Dopamine D1 receptor
External Links
UniProt	P18901
EMBL	M35077 S46131
PIR	A36049
UniGene	Rn.24039
ProteinModelPortal	P18901
SMR	P18901
BioGrid	246496
DIP	DIP-49024N
STRING	10116.ENSRNOP00000034820
BindingDB	P18901
ChEMBL	CHEMBL265
GuidetoPHARMACOLOGY	214
iPTMnet	P18901
PhosphoSitePlus	P18901
PaxDb	P18901
RGD	2518
eggNOG	KOG3656 ENOG410XRW9
HOGENOM	HOG000239242
HOVERGEN	HBG106962
InParanoid	P18901
PhylomeDB	P18901
PRO	PR:P18901
Proteomes	UP000002494
GO	GO:0030424 GO:0043679 GO:0005901 GO:0030425 GO:0043198 GO:0043197 GO:0044327 GO:0044326 GO:0005783 GO:0005789 GO:0016021 GO:0005887 GO:0043025 GO:0005886 GO:0031701 GO:0051117 GO:0031750 GO:0035240 GO:0001588 GO:0008144 GO:0001965 GO:0004930 GO:0032403 GO:0046982 GO:0019903 GO:0005102 GO:0007190 GO:0007191 GO:0008306 GO:0048148 GO:0019722 GO:0071456 GO:0032869 GO:0007212 GO:0006886 GO:0007626 GO:0030336 GO:0042321 GO:0006469 GO:0035106 GO:0021769 GO:0031161 GO:0046488 GO:0060158 GO:0045762 GO:0010579 GO:0030819 GO:2000253 GO:1900273 GO:0045838 GO:0043269 GO:0048169 GO:0019229 GO:0014823 GO:0043200 GO:0001975 GO:0042493 GO:0032355 GO:0045471 GO:0032094 GO:0043278 GO:0035094 GO:0014070 GO:0010243 GO:0032526 GO:0048545 GO:0035176 GO:0021756 GO:0007416 GO:0001963 GO:0042311 GO:0008542
InterPro	IPR001413 IPR000929 IPR000276 IPR017452
Pfam	PF00001
PRINTS	PR00565 PR00242 PR00237
SMART	SM01381
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Colocalizes with	GO:0005903	brush border	PMID:25825816^[1]	ECO:0000314			C		Figure 4B: Dopamine D1 receptor colocalizes at the brush border of renal proximal tubule cells in rat kidney.	complete CACAO 12306
Colocalizes with	GO:0005899	insulin receptor complex	PMID:25825816^[1]	ECO:0000314			C		Figure 4B: Dopamine D1 receptor colocalized with the IR at the brush border of renal proximal tubule cells in rat kidney.	complete CACAO 12307
involved_in	GO:0007416	synapse assembly	PMID:10051231^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	PMID:18424554^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	PMID:8702641^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:18424554^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0099170	postsynaptic modulation of chemical synaptic transmission	PMID:15175382^[5]	ECO:0006054	pharmacological assay evidence used in manual assertion		P	occurs_in:(UBERON:0001950)	Seeded From UniProt	complete
involved_in	GO:0099170	postsynaptic modulation of chemical synaptic transmission	PMID:15175382^[5]	ECO:0006013	patch-clamp recording evidence used in manual assertion		P	occurs_in:(UBERON:0001950)	Seeded From UniProt	complete
part_of	GO:0099056	integral component of presynaptic membrane	PMID:18340460^[6]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0001876)	Seeded From UniProt	complete
part_of	GO:0099055	integral component of postsynaptic membrane	PMID:18340460^[6]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0001876)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:18340460^[6]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0001876)	Seeded From UniProt	complete
involved_in	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	PMID:12688394^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	PMID:15351518^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006886	intracellular protein transport	PMID:16641250^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006469	negative regulation of protein kinase activity	PMID:12688394^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005901	caveola	PMID:15265765^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:17576511^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	PMID:17576511^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:12408866^[12]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2737	F		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:12408866^[12]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2736	F		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	PMID:11818555^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0001975	response to amphetamine	PMID:19145071^[14]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0001965	G-protein alpha-subunit binding	PMID:15798088^[15]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2716	F		Seeded From UniProt	complete
involved_in	GO:0001963	synaptic transmission, dopaminergic	PMID:16855100^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001963	synaptic transmission, dopaminergic	PMID:17314300^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:26277342^[18]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	PMID:16855100^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	PMID:17314300^[17]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	PMID:11818555^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:2000253	positive regulation of feeding behavior	PMID:11705777^[19]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1900273	positive regulation of long-term synaptic potentiation	PMID:20377617^[20]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071456	cellular response to hypoxia	PMID:20969567^[21]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	PMID:27638511^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0051117	ATPase binding	PMID:21809413^[23]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2169	F		Seeded From UniProt	complete
enables	GO:0051117	ATPase binding	PMID:20623535^[24]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:621594	F		Seeded From UniProt	complete
involved_in	GO:0048545	response to steroid hormone	PMID:18809391^[25]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048169	regulation of long-term neuronal synaptic plasticity	PMID:16855100^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048148	behavioral response to cocaine	PMID:16377433^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	PMID:22986162^[27]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2520	F		Seeded From UniProt	complete
involved_in	GO:0045838	positive regulation of membrane potential	PMID:18662324^[28]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045471	response to ethanol	PMID:23873704^[29]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	PMID:22843680^[30]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:621719 RGD:68424	F		Seeded From UniProt	complete
part_of	GO:0044327	dendritic spine head	PMID:21809413^[23]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0044326	dendritic spine neck	PMID:21809413^[23]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043679	axon terminus	PMID:17576511^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0043278	response to morphine	PMID:23775491^[31]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043269	regulation of ion transport	PMID:14983054^[32]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043200	response to amino acid	PMID:17052844^[33]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0043198	dendritic shaft	PMID:16228995^[34]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	PMID:11818555^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	PMID:17576511^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0042755	eating behavior	PMID:12944496^[35]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	PMID:16499906^[36]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	PMID:15798088^[15]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	PMID:12944496^[35]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	PMID:21557291^[37]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035106	operant conditioning	PMID:15245880^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035094	response to nicotine	PMID:23447334^[39]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032869	cellular response to insulin stimulus	PMID:12707290^[40]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032526	response to retinoic acid	PMID:15939542^[41]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032355	response to estradiol	PMID:20534718^[42]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032094	response to food	PMID:20875839^[43]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031750	D3 dopamine receptor binding	PMID:14732731^[44]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2521	F		Seeded From UniProt	complete
enables	GO:0031701	angiotensin receptor binding	PMID:22193384^[45]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2070	F		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:16641250^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:17576511^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0030336	negative regulation of cell migration	PMID:12688394^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021769	orbitofrontal cortex development	PMID:22015925^[46]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021756	striatum development	PMID:22015925^[46]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0019903	protein phosphatase binding	PMID:23328768^[47]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:3447	F		Seeded From UniProt	complete
involved_in	GO:0019722	calcium-mediated signaling	PMID:14983054^[32]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019229	regulation of vasoconstriction	PMID:15778266^[48]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	PMID:11818555^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0014823	response to activity	PMID:19759268^[49]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	PMID:20673846^[50]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010243	response to organonitrogen compound	PMID:23876469^[51]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008542	visual learning	PMID:16855100^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008306	associative learning	PMID:15245880^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008306	associative learning	PMID:23437091^[52]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008144	drug binding	PMID:17314300^[17]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0008144	drug binding	PMID:16855100^[16]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007626	locomotory behavior	PMID:16377433^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007625	grooming behavior	PMID:12944496^[35]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007212	dopamine receptor signaling pathway	PMID:16855100^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007212	dopamine receptor signaling pathway	PMID:17314300^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0030594	neurotransmitter receptor activity	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:71034	F		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2342 RGD:2343 RGD:2518 RGD:2522 RGD:2851 RGD:61800 RGD:61801 RGD:620023 RGD:62044 RGD:71034	C		Seeded From UniProt	complete
involved_in	GO:0007268	chemical synaptic transmission	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2830 RGD:2846	P		Seeded From UniProt	complete
involved_in	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2851 RGD:62044	P		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000037 PANTHER:PTN000664111 RGD:2343 UniProtKB:P08172 UniProtKB:P08908 UniProtKB:P21917 UniProtKB:P28221 UniProtKB:P28222 UniProtKB:P28335 UniProtKB:P28566 UniProtKB:P30546 UniProtKB:P30939 WB:WBGene00001519	C		Seeded From UniProt	complete
enables	GO:0004993	G protein-coupled serotonin receptor activity	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004168 FB:FBgn0004573 FB:FBgn0087012 FB:FBgn0263116 MGI:MGI:109323 MGI:MGI:96273 MGI:MGI:96274 MGI:MGI:96276 MGI:MGI:96281 MGI:MGI:96284 PANTHER:PTN000664111 RGD:2845 RGD:2846 RGD:2848 RGD:2850 RGD:2851 RGD:61800 RGD:62044 RGD:62388 RGD:71034 UniProtKB:A0A0B4KFU6 UniProtKB:P08908 UniProtKB:P28221 UniProtKB:P28222 UniProtKB:P28223 UniProtKB:P28335 UniProtKB:P28566 UniProtKB:P30939 UniProtKB:P41595 UniProtKB:P47898 UniProtKB:Q13639 WB:WBGene00004776 WB:WBGene00004779	F		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	PMID:21873635^[53]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2518	F		Seeded From UniProt	complete
involved_in	GO:0098664	G protein-coupled serotonin receptor signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004993	P		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F		Seeded From UniProt	complete
enables	GO:0004952	dopamine neurotransmitter receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001413	F		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001413	C		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	P		Seeded From UniProt	complete
involved_in	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001413	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR017452	C		Seeded From UniProt	complete
involved_in	GO:0042311	vasodilation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001413	P		Seeded From UniProt	complete
involved_in	GO:0007212	dopamine receptor signaling pathway	PMID:11818555^[13]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0284	C		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0097	C		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0283	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Li, F et al. (2015) Sorting nexin 5 and dopamine d1 receptor regulate the expression of the insulin receptor in human renal proximal tubule cells. Endocrinology 156 2211-21 PubMed GONUTS page
↑ Wong, AC et al. (1999) D1- and D2-like dopamine receptors are co-localized on the presynaptic varicosities of striatal and nucleus accumbens neurons in vitro. Neuroscience 89 221-33 PubMed GONUTS page
↑ ^3.0 ^3.1 Fiorentini, C et al. (2008) Reciprocal regulation of dopamine D1 and D3 receptor function and trafficking by heterodimerization. Mol. Pharmacol. 74 59-69 PubMed GONUTS page
↑ Yu, PY et al. (1996) Dopamine D1A receptor regulation of phospholipase C isoform. J. Biol. Chem. 271 19503-8 PubMed GONUTS page
↑ ^5.0 ^5.1 Tseng, KY & O'Donnell, P (2004) Dopamine-glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms. J. Neurosci. 24 5131-9 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Pinto, A & Sesack, SR (2008) Ultrastructural analysis of prefrontal cortical inputs to the rat amygdala: spatial relationships to presumed dopamine axons and D1 and D2 receptors. Brain Struct Funct 213 159-75 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Yasunari, K et al. (2003) Dopamine as a novel anti-migration factor of vascular smooth muscle cells through D1A and D1B receptors. J. Cardiovasc. Pharmacol. 41 Suppl 1 S33-8 PubMed GONUTS page
↑ Diaz, LM et al. (2004) Sindbis viral-mediated expression of eGFP-dopamine D1 receptors in situ with real-time two-photon microscopic detection. J. Neurosci. Methods 139 25-31 PubMed GONUTS page
↑ ^9.0 ^9.1 Hallett, PJ et al. (2006) Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking. J. Neurosci. 26 4690-700 PubMed GONUTS page
↑ Trivedi, M et al. (2004) Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules. Am. J. Physiol. Renal Physiol. 287 F921-31 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 Jan, C et al. (2007) Localization of D1a dopamine receptors on cell bodies and axonal endings in the substantia nigra pars reticulata of the rat. J Neural Transm (Vienna) 114 1509-17 PubMed GONUTS page
↑ ^12.0 ^12.1 Lee, FJ et al. (2002) Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor. Cell 111 219-30 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 ^13.3 ^13.4 Scott, L et al. (2002) Selective up-regulation of dopamine D1 receptors in dendritic spines by NMDA receptor activation. Proc. Natl. Acad. Sci. U.S.A. 99 1661-4 PubMed GONUTS page
↑ Mukda, S et al. (2009) Amphetamine-induced changes in dopamine receptors in early postnatal rat brain. Dev. Neurosci. 31 193-201 PubMed GONUTS page
↑ ^15.0 ^15.1 Trivedi, M & Lokhandwala, MF (2005) Rosiglitazone restores renal D1A receptor-Gs protein coupling by reducing receptor hyperphosphorylation in obese rats. Am. J. Physiol. Renal Physiol. 289 F298-304 PubMed GONUTS page
↑ ^16.0 ^16.1 ^16.2 ^16.3 ^16.4 ^16.5 Lemon, N & Manahan-Vaughan, D (2006) Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. J. Neurosci. 26 7723-9 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 ^17.3 Floresco, SB & Tse, MT (2007) Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala-prefrontal cortical pathway. J. Neurosci. 27 2045-57 PubMed GONUTS page
↑ Mao, LM & Wang, JQ (2015) Dopaminergic and cholinergic regulation of Fyn tyrosine kinase phosphorylation in the rat striatum in vivo. Neuropharmacology 99 491-9 PubMed GONUTS page
↑ Sato, T et al. (2001) Hypothalamic dopaminergic receptor expressions in anorexia of tumor-bearing rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 R1907-16 PubMed GONUTS page
↑ Krishnan, B et al. (2010) Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal. Eur. J. Neurosci. 31 1027-42 PubMed GONUTS page
↑ Raghuraman, G et al. (2010) Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling. J. Neurochem. 115 1568-78 PubMed GONUTS page
↑ Tapia-Bustos, A et al. (2017) Modulation of Postnatal Neurogenesis by Perinatal Asphyxia: Effect of D and D Dopamine Receptor Agonists. Neurotox Res 31 109-121 PubMed GONUTS page
↑ ^23.0 ^23.1 ^23.2 Blom, H et al. (2012) Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy. Microsc. Res. Tech. 75 220-8 PubMed GONUTS page
↑ Chen, S & Liu, F (2010) Interaction of dopamine D1 receptor with N-ethylmaleimide-sensitive factor is important for the membrane localization of the receptor. J. Neurosci. Res. 88 2504-12 PubMed GONUTS page
↑ Birgner, C et al. (2008) The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors. Brain Res. 1240 221-8 PubMed GONUTS page
↑ ^26.0 ^26.1 Festa, ED et al. (2006) Cocaine-induced sex differences in D1 receptor activation and binding levels after acute cocaine administration. Brain Res. Bull. 68 277-84 PubMed GONUTS page
↑ Perreault, ML et al. (2012) Reduced striatal dopamine D1-D2 receptor heteromer expression and behavioural subsensitivity in juvenile rats. Neuroscience 225 130-9 PubMed GONUTS page
↑ Martina, M & Bergeron, R (2008) D1 and D4 dopaminergic receptor interplay mediates coincident G protein-independent and dependent regulation of glutamate NMDA receptors in the lateral amygdala. J. Neurochem. 106 2421-35 PubMed GONUTS page
↑ Li, J et al. (2013) MicroRNA expression profile and functional analysis reveal that miR-382 is a critical novel gene of alcohol addiction. EMBO Mol Med 5 1402-14 PubMed GONUTS page
↑ Ha, CM et al. (2012) Calcyon forms a novel ternary complex with dopamine D1 receptor through PSD-95 protein and plays a role in dopamine receptor internalization. J. Biol. Chem. 287 31813-22 PubMed GONUTS page
↑ Sun, L et al. (2014) Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal. Brain Struct Funct 219 1755-71 PubMed GONUTS page
↑ ^32.0 ^32.1 Chen, G et al. (2004) Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex. Proc. Natl. Acad. Sci. U.S.A. 101 2596-600 PubMed GONUTS page
↑ Binienda, ZK et al. (2006) Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine. Neurosci. Lett. 410 62-5 PubMed GONUTS page
↑ Hara, Y & Pickel, VM (2005) Overlapping intracellular and differential synaptic distributions of dopamine D1 and glutamate N-methyl-D-aspartate receptors in rat nucleus accumbens. J. Comp. Neurol. 492 442-55 PubMed GONUTS page
↑ ^35.0 ^35.1 ^35.2 Isaac, SO & Berridge, CW (2003) Wake-promoting actions of dopamine D1 and D2 receptor stimulation. J. Pharmacol. Exp. Ther. 307 386-94 PubMed GONUTS page
↑ Huzarska, M et al. (2006) Repeated treatment with antidepressants enhances dopamine D1 receptor gene expression in the rat brain. Eur. J. Pharmacol. 532 208-13 PubMed GONUTS page
↑ Zenko, M et al. (2011) Requirement for the endocannabinoid system in social interaction impairment induced by coactivation of dopamine D1 and D2 receptors in the piriform cortex. J. Neurosci. Res. 89 1245-58 PubMed GONUTS page
↑ ^38.0 ^38.1 Braszko, JJ (2004) Involvement of D1 dopamine receptors in the cognitive effects of angiotensin IV and des-Phe6 angiotensin IV. Peptides 25 1195-203 PubMed GONUTS page
↑ Gozen, O et al. (2013) The epigenetic effect of nicotine on dopamine D1 receptor expression in rat prefrontal cortex. Synapse 67 545-52 PubMed GONUTS page
↑ Banday, AA et al. (2003) Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin. Hypertension 41 1353-8 PubMed GONUTS page
↑ Wang, HF & Liu, FC (2005) Regulation of multiple dopamine signal transduction molecules by retinoids in the developing striatum. Neuroscience 134 97-105 PubMed GONUTS page
↑ Sárvári, M et al. (2010) Estradiol replacement alters expression of genes related to neurotransmission and immune surveillance in the frontal cortex of middle-aged, ovariectomized rats. Endocrinology 151 3847-62 PubMed GONUTS page
↑ Alsiö, J et al. (2010) Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats. Neuroscience 171 779-87 PubMed GONUTS page
↑ Zeng, C et al. (2004) Aberrant D1 and D3 dopamine receptor transregulation in hypertension. Hypertension 43 654-60 PubMed GONUTS page
↑ Li, D et al. (2012) Binding of losartan to angiotensin AT1 receptors increases dopamine D1 receptor activation. J. Am. Soc. Nephrol. 23 421-8 PubMed GONUTS page
↑ ^46.0 ^46.1 Sillivan, SE & Konradi, C (2011) Expression and function of dopamine receptors in the developing medial frontal cortex and striatum of the rat. Neuroscience 199 501-14 PubMed GONUTS page
↑ Fiorentini, C et al. (2013) Persistent activation of the D1R/Shp-2/Erk1/2 pathway in l-DOPA-induced dyskinesia in the 6-hydroxy-dopamine rat model of Parkinson's disease. Neurobiol. Dis. 54 339-48 PubMed GONUTS page
↑ Akerman, S & Goadsby, PJ (2005) The role of dopamine in a model of trigeminovascular nociception. J. Pharmacol. Exp. Ther. 314 162-9 PubMed GONUTS page
↑ George, L et al. (2009) Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats. Am. J. Physiol. Renal Physiol. 297 F1174-80 PubMed GONUTS page
↑ Dalton, VS & Zavitsanou, K (2010) Differential treatment regimen-related effects of cannabinoids on D1 and D2 receptors in adolescent and adult rat brain. J. Chem. Neuroanat. 40 272-80 PubMed GONUTS page
↑ Banday, AA & Lokhandwala, MF (2013) Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress. Hypertension 62 512-7 PubMed GONUTS page
↑ Garske, AK et al. (2013) Adolescent changes in dopamine D1 receptor expression in orbitofrontal cortex and piriform cortex accompany an associative learning deficit. PLoS ONE 8 e56191 PubMed GONUTS page
↑ ^53.0 ^53.1 ^53.2 ^53.3 ^53.4 ^53.5 ^53.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:25825816-1] 1.0 ^1.1 Li, F et al. (2015) Sorting nexin 5 and dopamine d1 receptor regulate the expression of the insulin receptor in human renal proximal tubule cells. Endocrinology 156 2211-21 PubMed GONUTS page

[PMID:10051231-2] Wong, AC et al. (1999) D1- and D2-like dopamine receptors are co-localized on the presynaptic varicosities of striatal and nucleus accumbens neurons in vitro. Neuroscience 89 221-33 PubMed GONUTS page

[PMID:18424554-3] 3.0 ^3.1 Fiorentini, C et al. (2008) Reciprocal regulation of dopamine D1 and D3 receptor function and trafficking by heterodimerization. Mol. Pharmacol. 74 59-69 PubMed GONUTS page

[PMID:8702641-4] Yu, PY et al. (1996) Dopamine D1A receptor regulation of phospholipase C isoform. J. Biol. Chem. 271 19503-8 PubMed GONUTS page

[PMID:15175382-5] 5.0 ^5.1 Tseng, KY & O'Donnell, P (2004) Dopamine-glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms. J. Neurosci. 24 5131-9 PubMed GONUTS page

[PMID:18340460-6] 6.0 ^6.1 ^6.2 Pinto, A & Sesack, SR (2008) Ultrastructural analysis of prefrontal cortical inputs to the rat amygdala: spatial relationships to presumed dopamine axons and D1 and D2 receptors. Brain Struct Funct 213 159-75 PubMed GONUTS page

[PMID:12688394-7] 7.0 ^7.1 ^7.2 Yasunari, K et al. (2003) Dopamine as a novel anti-migration factor of vascular smooth muscle cells through D1A and D1B receptors. J. Cardiovasc. Pharmacol. 41 Suppl 1 S33-8 PubMed GONUTS page

[PMID:15351518-8] Diaz, LM et al. (2004) Sindbis viral-mediated expression of eGFP-dopamine D1 receptors in situ with real-time two-photon microscopic detection. J. Neurosci. Methods 139 25-31 PubMed GONUTS page

[PMID:16641250-9] 9.0 ^9.1 Hallett, PJ et al. (2006) Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking. J. Neurosci. 26 4690-700 PubMed GONUTS page

[PMID:15265765-10] Trivedi, M et al. (2004) Dopamine recruits D1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules. Am. J. Physiol. Renal Physiol. 287 F921-31 PubMed GONUTS page

[PMID:17576511-11] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 Jan, C et al. (2007) Localization of D1a dopamine receptors on cell bodies and axonal endings in the substantia nigra pars reticulata of the rat. J Neural Transm (Vienna) 114 1509-17 PubMed GONUTS page

[PMID:12408866-12] 12.0 ^12.1 Lee, FJ et al. (2002) Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor. Cell 111 219-30 PubMed GONUTS page

[PMID:11818555-13] 13.0 ^13.1 ^13.2 ^13.3 ^13.4 Scott, L et al. (2002) Selective up-regulation of dopamine D1 receptors in dendritic spines by NMDA receptor activation. Proc. Natl. Acad. Sci. U.S.A. 99 1661-4 PubMed GONUTS page

[PMID:19145071-14] Mukda, S et al. (2009) Amphetamine-induced changes in dopamine receptors in early postnatal rat brain. Dev. Neurosci. 31 193-201 PubMed GONUTS page

[PMID:15798088-15] 15.0 ^15.1 Trivedi, M & Lokhandwala, MF (2005) Rosiglitazone restores renal D1A receptor-Gs protein coupling by reducing receptor hyperphosphorylation in obese rats. Am. J. Physiol. Renal Physiol. 289 F298-304 PubMed GONUTS page

[PMID:16855100-16] 16.0 ^16.1 ^16.2 ^16.3 ^16.4 ^16.5 Lemon, N & Manahan-Vaughan, D (2006) Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. J. Neurosci. 26 7723-9 PubMed GONUTS page

[PMID:17314300-17] 17.0 ^17.1 ^17.2 ^17.3 Floresco, SB & Tse, MT (2007) Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala-prefrontal cortical pathway. J. Neurosci. 27 2045-57 PubMed GONUTS page

[PMID:26277342-18] Mao, LM & Wang, JQ (2015) Dopaminergic and cholinergic regulation of Fyn tyrosine kinase phosphorylation in the rat striatum in vivo. Neuropharmacology 99 491-9 PubMed GONUTS page

[PMID:11705777-19] Sato, T et al. (2001) Hypothalamic dopaminergic receptor expressions in anorexia of tumor-bearing rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 R1907-16 PubMed GONUTS page

[PMID:20377617-20] Krishnan, B et al. (2010) Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal. Eur. J. Neurosci. 31 1027-42 PubMed GONUTS page

[PMID:20969567-21] Raghuraman, G et al. (2010) Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling. J. Neurochem. 115 1568-78 PubMed GONUTS page

[PMID:27638511-22] Tapia-Bustos, A et al. (2017) Modulation of Postnatal Neurogenesis by Perinatal Asphyxia: Effect of D and D Dopamine Receptor Agonists. Neurotox Res 31 109-121 PubMed GONUTS page

[PMID:21809413-23] 23.0 ^23.1 ^23.2 Blom, H et al. (2012) Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy. Microsc. Res. Tech. 75 220-8 PubMed GONUTS page

[PMID:20623535-24] Chen, S & Liu, F (2010) Interaction of dopamine D1 receptor with N-ethylmaleimide-sensitive factor is important for the membrane localization of the receptor. J. Neurosci. Res. 88 2504-12 PubMed GONUTS page

[PMID:18809391-25] Birgner, C et al. (2008) The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors. Brain Res. 1240 221-8 PubMed GONUTS page

[PMID:16377433-26] 26.0 ^26.1 Festa, ED et al. (2006) Cocaine-induced sex differences in D1 receptor activation and binding levels after acute cocaine administration. Brain Res. Bull. 68 277-84 PubMed GONUTS page

[PMID:22986162-27] Perreault, ML et al. (2012) Reduced striatal dopamine D1-D2 receptor heteromer expression and behavioural subsensitivity in juvenile rats. Neuroscience 225 130-9 PubMed GONUTS page

[PMID:18662324-28] Martina, M & Bergeron, R (2008) D1 and D4 dopaminergic receptor interplay mediates coincident G protein-independent and dependent regulation of glutamate NMDA receptors in the lateral amygdala. J. Neurochem. 106 2421-35 PubMed GONUTS page

[PMID:23873704-29] Li, J et al. (2013) MicroRNA expression profile and functional analysis reveal that miR-382 is a critical novel gene of alcohol addiction. EMBO Mol Med 5 1402-14 PubMed GONUTS page

[PMID:22843680-30] Ha, CM et al. (2012) Calcyon forms a novel ternary complex with dopamine D1 receptor through PSD-95 protein and plays a role in dopamine receptor internalization. J. Biol. Chem. 287 31813-22 PubMed GONUTS page

[PMID:23775491-31] Sun, L et al. (2014) Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal. Brain Struct Funct 219 1755-71 PubMed GONUTS page

[PMID:14983054-32] 32.0 ^32.1 Chen, G et al. (2004) Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex. Proc. Natl. Acad. Sci. U.S.A. 101 2596-600 PubMed GONUTS page

[PMID:17052844-33] Binienda, ZK et al. (2006) Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine. Neurosci. Lett. 410 62-5 PubMed GONUTS page

[PMID:16228995-34] Hara, Y & Pickel, VM (2005) Overlapping intracellular and differential synaptic distributions of dopamine D1 and glutamate N-methyl-D-aspartate receptors in rat nucleus accumbens. J. Comp. Neurol. 492 442-55 PubMed GONUTS page

[PMID:12944496-35] 35.0 ^35.1 ^35.2 Isaac, SO & Berridge, CW (2003) Wake-promoting actions of dopamine D1 and D2 receptor stimulation. J. Pharmacol. Exp. Ther. 307 386-94 PubMed GONUTS page

[PMID:16499906-36] Huzarska, M et al. (2006) Repeated treatment with antidepressants enhances dopamine D1 receptor gene expression in the rat brain. Eur. J. Pharmacol. 532 208-13 PubMed GONUTS page

[PMID:21557291-37] Zenko, M et al. (2011) Requirement for the endocannabinoid system in social interaction impairment induced by coactivation of dopamine D1 and D2 receptors in the piriform cortex. J. Neurosci. Res. 89 1245-58 PubMed GONUTS page

[PMID:15245880-38] 38.0 ^38.1 Braszko, JJ (2004) Involvement of D1 dopamine receptors in the cognitive effects of angiotensin IV and des-Phe6 angiotensin IV. Peptides 25 1195-203 PubMed GONUTS page

[PMID:23447334-39] Gozen, O et al. (2013) The epigenetic effect of nicotine on dopamine D1 receptor expression in rat prefrontal cortex. Synapse 67 545-52 PubMed GONUTS page

[PMID:12707290-40] Banday, AA et al. (2003) Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin. Hypertension 41 1353-8 PubMed GONUTS page

[PMID:15939542-41] Wang, HF & Liu, FC (2005) Regulation of multiple dopamine signal transduction molecules by retinoids in the developing striatum. Neuroscience 134 97-105 PubMed GONUTS page

[PMID:20534718-42] Sárvári, M et al. (2010) Estradiol replacement alters expression of genes related to neurotransmission and immune surveillance in the frontal cortex of middle-aged, ovariectomized rats. Endocrinology 151 3847-62 PubMed GONUTS page

[PMID:20875839-43] Alsiö, J et al. (2010) Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats. Neuroscience 171 779-87 PubMed GONUTS page

[PMID:14732731-44] Zeng, C et al. (2004) Aberrant D1 and D3 dopamine receptor transregulation in hypertension. Hypertension 43 654-60 PubMed GONUTS page

[PMID:22193384-45] Li, D et al. (2012) Binding of losartan to angiotensin AT1 receptors increases dopamine D1 receptor activation. J. Am. Soc. Nephrol. 23 421-8 PubMed GONUTS page

[PMID:22015925-46] 46.0 ^46.1 Sillivan, SE & Konradi, C (2011) Expression and function of dopamine receptors in the developing medial frontal cortex and striatum of the rat. Neuroscience 199 501-14 PubMed GONUTS page

[PMID:23328768-47] Fiorentini, C et al. (2013) Persistent activation of the D1R/Shp-2/Erk1/2 pathway in l-DOPA-induced dyskinesia in the 6-hydroxy-dopamine rat model of Parkinson's disease. Neurobiol. Dis. 54 339-48 PubMed GONUTS page

[PMID:15778266-48] Akerman, S & Goadsby, PJ (2005) The role of dopamine in a model of trigeminovascular nociception. J. Pharmacol. Exp. Ther. 314 162-9 PubMed GONUTS page

[PMID:19759268-49] George, L et al. (2009) Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats. Am. J. Physiol. Renal Physiol. 297 F1174-80 PubMed GONUTS page

[PMID:20673846-50] Dalton, VS & Zavitsanou, K (2010) Differential treatment regimen-related effects of cannabinoids on D1 and D2 receptors in adolescent and adult rat brain. J. Chem. Neuroanat. 40 272-80 PubMed GONUTS page

[PMID:23876469-51] Banday, AA & Lokhandwala, MF (2013) Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress. Hypertension 62 512-7 PubMed GONUTS page

[PMID:23437091-52] Garske, AK et al. (2013) Adolescent changes in dopamine D1 receptor expression in orbitofrontal cortex and piriform cortex accompany an associative learning deficit. PLoS ONE 8 e56191 PubMed GONUTS page

[PMID:21873635-53] 53.0 ^53.1 ^53.2 ^53.3 ^53.4 ^53.5 ^53.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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RAT:DRD1

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