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Category:Team Apple bottom genes

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableHUMAN:CTSL2Amendes, Team Apple bottom genes2016-04-19 02:22:48 CDTGO:0000790 nuclear chromatin (C)PMID:26920047ECO:0000314 direct assay evidence used in manual assertion

Fg. 5B dynamic SCP4 relocation from the chromatin, out of the nucleus, and towards the cytoplasm.

challenge
unacceptableHUMAN:CTSL2Amendes, Team Apple bottom genes2016-04-19 02:12:24 CDTGO:0004647 phosphoserine phosphatase activity (F)PMID:26920047ECO:0000314 direct assay evidence used in manual assertion

Fg. 2C SCP4 can function as a Ser5-specific CTD phosphatase in cells.

challenge
acceptableHUMAN:SNP23Alambert, Team Apple bottom genes2016-04-19 02:05:57 CDTGO:0005739 mitochondrion (C)PMID:26733245ECO:0000314 direct assay evidence used in manual assertion

Figure 3

challenge
acceptableHUMAN:CTSL2Amendes, Team Apple bottom genes2016-04-19 02:04:41 CDTGO:0008420 CTD phosphatase activity (F)PMID:26920047ECO:0000314 direct assay evidence used in manual assertion

Fg 1B. SCP4 functions as a

Ser5-preferential CTD phosphatase in cells.

challenge
acceptableHUMAN:SNP23Alambert, Team Apple bottom genes2016-04-19 01:58:29 CDTGO:0005886 plasma membrane (C)PMID:26733245ECO:0000314 direct assay evidence used in manual assertion

Figure 3

challenge
updatedbyinstructorHUMAN:CTSL2Amendes, Team Apple bottom genes2016-04-19 01:54:11 CDTGO:0005737 cytoplasm (C)PMID:26920047ECO:0000314 direct assay evidence used in manual assertion

Fg. 5C Immunostaining of hemintreated

cells revealed time-dependent accumulation of SCP4 in the cytoplasm.

challenge
unacceptableMOUSE:NEIL2Alambert, Team Apple bottom genes2016-04-18 10:38:58 CDTGO:0032300 mismatch repair complex (C)PMID:21169365ECO:0000314 direct assay evidence used in manual assertion

Figure 4A

challenge
unacceptableHUMAN:TERF2Amendes, Team Apple bottom genes2016-04-15 10:02:47 CDTPMID:26856421ECO:0000314 direct assay evidence used in manual assertion

Fg. 4d 4e: shows DNA binding

challenge
acceptableMOUSE:HNRPDAmendes, Team Apple bottom genes2016-04-12 10:08:20 CDTGO:0000790 nuclear chromatin (C)PMID:27034373ECO:0000314 direct assay evidence used in manual assertion

Fg.S7G Chip of hnrpd shows enrichment in chromatin.

challenge
unacceptableMOUSE:HNRPDAmendes, Team Apple bottom genes2016-04-12 09:51:29 CDTGO:0071222 cellular response to lipopolysaccharide (P)PMID:27034373ECO:0000315 mutant phenotype evidence used in manual assertion

Fg. 4C An increased gene expression response to LPS when hnrnpd is knocked out.

challenge
unacceptableMOUSE:DCP2Amendes, Team Apple bottom genes2016-04-12 09:34:18 CDTGO:0071222 cellular response to lipopolysaccharide (P)PMID:27034373ECO:0000315 mutant phenotype evidence used in manual assertion

In Fig.3E the up regulation of the non coding RNA after LPS exposure is diminished in the Dcp2 knockout in the bone marrow derived mouse macrophages

challenge

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Pages in category "Team Apple bottom genes"

The following 2 pages are in this category, out of 2 total.

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