HUMAN:CTSL2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	CTDSPL2
Protein Name(s)	CTD small phosphatase-like protein 2 CTDSP-like 2
External Links
UniProt	Q05D32
EMBL	AY364237 DQ128104 AF161543 AF161478 AK001385 AK291230 CR627421 CH471082 BC018623 BC035744
CCDS	CCDS10110.1
RefSeq	NP_057480.2 XP_005254498.1 XP_006720628.1
UniGene	Hs.497967
ProteinModelPortal	Q05D32
SMR	Q05D32
BioGrid	119571
IntAct	Q05D32
MINT	MINT-5009084
STRING	9606.ENSP00000260327
DEPOD	Q05D32
iPTMnet	Q05D32
BioMuta	CTDSPL2
DMDM	187471086
EPD	Q05D32
MaxQB	Q05D32
PaxDb	Q05D32
PeptideAtlas	Q05D32
PRIDE	Q05D32
DNASU	51496
Ensembl	ENST00000260327 ENST00000558373 ENST00000558966
GeneID	51496
KEGG	hsa:51496
UCSC	uc001ztr.4
CTD	51496
GeneCards	CTDSPL2
HGNC	HGNC:26936
HPA	HPA040763
neXtProt	NX_Q05D32
PharmGKB	PA142672063
eggNOG	KOG1605 COG5190
GeneTree	ENSGT00390000017194
HOVERGEN	HBG107781
InParanoid	Q05D32
KO	K17616
OMA	YTSQAVQ
OrthoDB	EOG7Q8CP4
PhylomeDB	Q05D32
TreeFam	TF354278
ChiTaRS	CTDSPL2
GenomeRNAi	51496
NextBio	55167
PRO	PR:Q05D32
Proteomes	UP000005640
Bgee	Q05D32
CleanEx	HS_CTDSPL2
ExpressionAtlas	Q05D32
Genevisible	Q05D32
GO	GO:0005654 GO:0004721 GO:0030514 GO:0046827
Gene3D	3.40.50.1000
InterPro	IPR011948 IPR004274 IPR023214
Pfam	PF03031
SMART	SM00577
SUPFAM	SSF56784
TIGRFAMs	TIGR02251
PROSITE	PS50969

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Colocalizes with	GO:0005737	cytoplasm	PMID:26920047	ECO:0000314			C		Fg. 5C Immunostaining of hemintreated cells revealed time-dependent accumulation of SCP4 in the cytoplasm.	complete CACAO 11789
	GO:0008420	CTD phosphatase activity	PMID:26920047	ECO:0000314			F		Fg 1B. SCP4 functions as a Ser5-preferential CTD phosphatase in cells.	complete CACAO 11792
	GO:0004647	phosphoserine phosphatase activity	PMID:26920047	ECO:0000314			F		Fg. 2C SCP4 can function as a Ser5-specific CTD phosphatase in cells.	complete CACAO 11795
	GO:0000790	nuclear chromatin	PMID:26920047	ECO:0000314			C		Fg. 5B dynamic SCP4 relocation from the chromatin, out of the nucleus, and towards the cytoplasm.	complete CACAO 11797
enables	GO:0004721	phosphoprotein phosphatase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1196405 PANTHER:PTN000258719 SGD:S000001046 SGD:S000003933 UniProtKB:Q3ZCQ8	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0046827	positive regulation of protein export from nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8BG15 ensembl:ENSMUSP00000047543	P		Seeded From UniProt	complete
involved_in	GO:0030514	negative regulation of BMP signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8BG15 ensembl:ENSMUSP00000047543	P		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8BG15 ensembl:ENSMUSP00000047543	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8BG15 ensembl:ENSMUSP00000047543	C		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8BG15 ensembl:ENSMUSP00000047543	F		Seeded From UniProt	complete
enables	GO:0016791	phosphatase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011948	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0904	F		Seeded From UniProt	complete
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References

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