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MOUSE:HNRPD
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Hnrnpd (synonyms: Auf1, Hnrpd) | |
Protein Name(s) | Heterogeneous nuclear ribonucleoprotein D0
hnRNP D0 AU-rich element RNA-binding protein 1 | |
External Links | ||
UniProt | Q60668 | |
EMBL | U11273 U11274 BC011172 BC049098 | |
CCDS | CCDS39180.1 CCDS39181.1 CCDS39182.1 CCDS51571.1 | |
PIR | I49069 I49070 | |
RefSeq | NP_001070733.1 NP_001070734.1 NP_001070735.1 NP_031542.2 XP_006534798.1 | |
UniGene | Mm.150231 | |
ProteinModelPortal | Q60668 | |
SMR | Q60668 | |
BioGrid | 198279 | |
DIP | DIP-31411N | |
IntAct | Q60668 | |
MINT | MINT-1864708 | |
STRING | 10090.ENSMUSP00000132735 | |
iPTMnet | Q60668 | |
PhosphoSite | Q60668 | |
SwissPalm | Q60668 | |
EPD | Q60668 | |
MaxQB | Q60668 | |
PaxDb | Q60668 | |
PRIDE | Q60668 | |
Ensembl | ENSMUST00000019128 ENSMUST00000172361 | |
GeneID | 11991 | |
KEGG | mmu:11991 | |
UCSC | uc008ygt.2 uc008ygu.2 | |
CTD | 3184 | |
MGI | MGI:101947 | |
eggNOG | KOG0118 COG0724 | |
GeneTree | ENSGT00760000118873 | |
HOGENOM | HOG000234441 | |
HOVERGEN | HBG002295 | |
InParanoid | Q60668 | |
KO | K13044 | |
OMA | TFKDEEP | |
OrthoDB | EOG715Q6V | |
PhylomeDB | Q60668 | |
TreeFam | TF314808 | |
Reactome | R-MMU-450408 R-MMU-72163 R-MMU-72203 | |
ChiTaRS | Hnrnpd | |
NextBio | 280159 | |
PRO | PR:Q60668 | |
Proteomes | UP000000589 | |
Bgee | Q60668 | |
ExpressionAtlas | Q60668 | |
Genevisible | Q60668 | |
GO | GO:0005829 GO:0070062 GO:0030529 GO:0005654 GO:0003680 GO:0003682 GO:0035925 GO:0000166 GO:0044822 GO:0003723 GO:0042162 GO:0061158 GO:0071230 GO:0071392 GO:0071732 GO:1904586 GO:0021549 GO:0097167 GO:1990828 GO:0001889 GO:0048255 GO:0045727 GO:0042752 GO:0043488 GO:0006355 GO:0051592 GO:0051602 GO:0014076 GO:1901355 GO:1904383 GO:0006351 | |
Gene3D | 3.30.70.330 | |
InterPro | IPR012956 IPR012677 IPR000504 | |
Pfam | PF08143 PF00076 | |
SMART | SM00360 | |
SUPFAM | SSF54928 | |
PROSITE | PS50102 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0071222 |
cellular response to lipopolysaccharide |
ECO:0000315 |
P |
Fg. 4C An increased gene expression response to LPS when hnrnpd is knocked out. |
complete | |||||
GO:0000790 |
nuclear chromatin |
ECO:0000314 |
C |
Fg.S7G Chip of hnrpd shows enrichment in chromatin. |
complete | |||||
involved_in |
GO:1905663 |
positive regulation of telomerase RNA reverse transcriptase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1904355 |
positive regulation of telomere capping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032204 |
regulation of telomere maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097167 |
circadian regulation of translation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045727 |
positive regulation of translation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042162 |
telomeric DNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003723 |
RNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
C |
part_of:(UBERON:0000955) |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0001230 |
mass spectrometry evidence used in manual assertion |
C |
part_of:(UBERON:0000955) |
Seeded From UniProt |
complete | ||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001215 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:1990837 |
sequence-specific double-stranded DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002545010 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1330294 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0035925 |
mRNA 3'-UTR AU-rich region binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002548379 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004838 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003729 |
mRNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002548379 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003723 |
RNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104819 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003680 |
AT DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002548379 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:1904586 |
cellular response to putrescine |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1904383 |
response to sodium phosphate |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1901355 |
response to rapamycin |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0097167 |
circadian regulation of translation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0071732 |
cellular response to nitric oxide |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0061158 |
3'-UTR-mediated mRNA destabilization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0051592 |
response to calcium ion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0048255 |
mRNA stabilization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0045727 |
positive regulation of translation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0043488 |
regulation of mRNA stability |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042826 |
histone deacetylase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042162 |
telomeric DNA binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0035925 |
mRNA 3'-UTR AU-rich region binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0010629 |
negative regulation of gene expression |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0010628 |
positive regulation of gene expression |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003729 |
mRNA binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003723 |
RNA binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003682 |
chromatin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003680 |
AT DNA binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620365 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097167 |
circadian regulation of translation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045727 |
positive regulation of translation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042162 |
telomeric DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003723 |
RNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q14103 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:1990828 |
hepatocyte dedifferentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904586 |
cellular response to putrescine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904383 |
response to sodium phosphate |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1901355 |
response to rapamycin |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071732 |
cellular response to nitric oxide |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071392 |
cellular response to estradiol stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071230 |
cellular response to amino acid stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061158 |
3'-UTR-mediated mRNA destabilization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051602 |
response to electrical stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051592 |
response to calcium ion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048255 |
mRNA stabilization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042826 |
histone deacetylase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0035925 |
mRNA 3'-UTR AU-rich region binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032355 |
response to estradiol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0021549 |
cerebellum development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010629 |
negative regulation of gene expression |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007420 |
brain development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003729 |
mRNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003682 |
chromatin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003680 |
AT DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001889 |
liver development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9JJ54 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A024RDF3 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
regulates_transcription_of:(ENSEMBL:ENSMUSG00000021611) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042789 |
mRNA transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_direct_input:(ENSEMBL:ENSMUSG00000021611) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042789 |
mRNA transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_direct_input:(ENSEMBL:ENSMUSG00000021611) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
regulates_transcription_of:(ENSEMBL:ENSMUSG00000021611) |
Seeded From UniProt |
complete | ||
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048511 |
rhythmic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Castellanos-Rubio, A et al. (2016) A long noncoding RNA associated with susceptibility to celiac disease. Science 352 91-5 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Pont, AR et al. (2012) mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription. Mol. Cell 47 5-15 PubMed GONUTS page
- ↑ 3.0 3.1 Trinidad, JC et al. (2006) Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol. Cell Proteomics 5 914-22 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Raineri, I et al. (2004) Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res. 32 1279-88 PubMed GONUTS page
c
- GO:1904586 ! cellular response to putrescine
- GO:0071392 ! cellular response to estradiol stimulus
- GO:0071732 ! cellular response to nitric oxide
- GO:0071222 ! cellular response to lipopolysaccharide
- GO:0071230 ! cellular response to amino acid stimulus
- GO:0021549 ! cerebellum development
- Chordata
- GO:0003682 ! chromatin binding
- GO:0097167 ! circadian regulation of translation
- Craniata
- GO:0005737 ! cytoplasm
- GO:0005829 ! cytosol
g
m
n
p
r
- GO:0043488 ! regulation of mRNA stability
- GO:0032204 ! regulation of telomere maintenance
- GO:0042752 ! regulation of circadian rhythm
- GO:1901355 ! response to rapamycin
- GO:1904383 ! response to sodium phosphate
- GO:0032355 ! response to estradiol
- GO:0051602 ! response to electrical stimulus
- GO:0051592 ! response to calcium ion
- GO:0048511 ! rhythmic process
- GO:1990904 ! ribonucleoprotein complex
- GO:0003723 ! RNA binding
- Rodentia
s