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Category:GO:0043020 ! NADPH oxidase complex
name: NADPH oxidase complex
namespace: cellular_component
def: "A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2." [GOC:jl, PMID:11483596, PMID:12440767]
synonym: "flavocytochrome b558" NARROW []
synonym: "respiratory-burst oxidase" RELATED []
is_a: GO:0098797 ! plasma membrane protein complex
is_a: GO:1990204 ! oxidoreductase complex
AmiGO
<GOterm>GO:0043020</GOterm>
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