Category:GO:0004129 ! cytochrome-c oxidase activity

name: cytochrome-c oxidase activity
namespace: molecular_function
def: "Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O." [RHEA:11436]
comment: The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
synonym: "aa3-type cytochrome c oxidase" NARROW [EC:7.1.1.9]
synonym: "ba3-type cytochrome c oxidase" NARROW [EC:7.1.1.9]
synonym: "caa3-type cytochrome c oxidase" NARROW [EC:7.1.1.9]
synonym: "cbb3-type cytochrome c oxidase" NARROW [EC:7.1.1.9]
synonym: "complex IV (mitochondrial electron transport) activity" RELATED [EC:7.1.1.9]
synonym: "cytochrome a3 activity" NARROW [EC:7.1.1.9]
synonym: "cytochrome aa3 activity" NARROW [EC:7.1.1.9]
synonym: "cytochrome c oxidase activity" EXACT []
synonym: "cytochrome oxidase activity" RELATED [EC:7.1.1.9]
synonym: "indophenol oxidase" NARROW []
synonym: "indophenolase" NARROW []
synonym: "Warburg's respiratory enzyme activity" RELATED [EC:7.1.1.9]
xref: EC:7.1.1.9
xref: MetaCyc:CYTOCHROME-C-OXIDASE-RXN
xref: RHEA:11436
is_a: GO:0009055 ! electron transfer activity
is_a: GO:0015078 ! proton transmembrane transporter activity
is_a: GO:0015453 ! oxidoreduction-driven active transmembrane transporter activity
is_a: GO:0016675 ! oxidoreductase activity, acting on a heme group of donors
is_a: GO:0022853 ! active monoatomic ion transmembrane transporter activity

AmiGO <GOterm>GO:0004129</GOterm>
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