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YEAST:COX4
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | COX4 | |
| Protein Name(s) | Cytochrome c oxidase subunit 4, mitochondrial
Cytochrome c oxidase polypeptide IV | |
| External Links | ||
| UniProt | P04037 | |
| EMBL | X01418 X91489 Z72709 EF123139 Y00152 BK006941 | |
| PIR | A22786 | |
| RefSeq | NP_011328.1 | |
| PDB | 1HR8 2ODX | |
| PDBsum | 1HR8 2ODX | |
| ProteinModelPortal | P04037 | |
| SMR | P04037 | |
| BioGrid | 33068 | |
| DIP | DIP-2763N | |
| IntAct | P04037 | |
| MINT | MINT-521387 | |
| TCDB | 3.D.4.8.1 | |
| MaxQB | P04037 | |
| PaxDb | P04037 | |
| PeptideAtlas | P04037 | |
| EnsemblFungi | [example_ID YGL187C] | |
| GeneID | 852688 | |
| KEGG | sce:YGL187C | |
| CYGD | YGL187c | |
| SGD | S000003155 | |
| eggNOG | NOG326977 | |
| HOGENOM | HOG000184129 | |
| InParanoid | P04037 | |
| KO | K02265 | |
| OMA | ARCWECG | |
| OrthoDB | EOG7BS4NR | |
| BioCyc | MetaCyc:YGL187C-MONOMER YEAST:YGL187C-MONOMER | |
| Reactome | REACT_189012 | |
| UniPathway | UPA00705 | |
| EvolutionaryTrace | P04037 | |
| NextBio | 972014 | |
| PRO | PR:P04037 | |
| Proteomes | UP000002311 | |
| Genevestigator | P04037 | |
| GO | GO:0005743 GO:0005758 GO:0005751 GO:0005739 GO:0004129 GO:0008270 GO:0009060 GO:1902600 GO:0006123 | |
| Gene3D | 2.60.11.10 | |
| InterPro | IPR002124 IPR020893 | |
| PANTHER | PTHR10122 | |
| Pfam | PF01215 | |
| ProDom | PD007270 | |
| PROSITE | PS00848 PS51359 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0033617 |
mitochondrial respiratory chain complex IV assembly |
ECO:0000315 |
P |
Figure 2 (B). The lack of band in lane 14 and 16 compared to the WT bands at the specific high molecular weight of 230 and 440 kDa indicates the lack of complex IV in mutant cox4. |
complete | |||||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0033617 |
mitochondrial respiratory chain complex IV assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009060 |
aerobic respiration |
ECO:0000353 |
physical interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006123 |
mitochondrial electron transport, cytochrome c to oxygen |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005751 |
mitochondrial respiratory chain complex IV |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0004129 |
cytochrome-c oxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0004129 |
cytochrome-c oxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042776 |
mitochondrial ATP synthesis coupled proton transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000012880 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006123 |
mitochondrial electron transport, cytochrome c to oxygen |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000012880 |
P |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0004129 |
cytochrome-c oxidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000012880 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004129 |
cytochrome-c oxidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005740 |
mitochondrial envelope |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004129 |
cytochrome-c oxidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005758 |
mitochondrial intermembrane space |
Reactome:R-SCE-1268015 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
Reactome:R-SCE-1268019 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006119 |
oxidative phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00705 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Vukotic, M et al. (2012) Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Cell Metab. 15 336-47 PubMed GONUTS page
- ↑ Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
- ↑ Renvoisé, M et al. (2014) Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. J Proteomics 106 140-50 PubMed GONUTS page
- ↑ Su, CH et al. (2014) The Cox3p assembly module of yeast cytochrome oxidase. Mol. Biol. Cell 25 965-76 PubMed GONUTS page
- ↑ Eytan, GD & Schatz, G (1975) Cytochrome c oxidase from bakers' yeast. V. Arrangement of the subunits in the isolated and membrane-bound enzyme. J. Biol. Chem. 250 767-74 PubMed GONUTS page
- ↑ Coyne, HJ 3rd et al. (2007) The characterization and role of zinc binding in yeast Cox4. J. Biol. Chem. 282 8926-34 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Taanman, JW & Capaldi, RA (1992) Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme. J. Biol. Chem. 267 22481-5 PubMed GONUTS page
- ↑ Geier, BM et al. (1995) Kinetic properties and ligand binding of the eleven-subunit cytochrome-c oxidase from Saccharomyces cerevisiae isolated with a novel large-scale purification method. Eur. J. Biochem. 227 296-302 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
d
f
m
- GO:0016020 ! membrane
- GO:0046872 ! metal ion binding
- GO:0033617 ! mitochondrial cytochrome c oxidase assembly
- GO:0006123 ! mitochondrial electron transport, cytochrome c to oxygen
- GO:0005740 ! mitochondrial envelope
- GO:0005758 ! mitochondrial intermembrane space
- GO:0005743 ! mitochondrial inner membrane
- GO:0005739 ! mitochondrion
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