PIG:Q71KK5

Species (Taxon ID)	Sus scrofa (Pig). (9823)
Gene Name(s)	COI (ECO:0000313 with EMBL:AAQ05995.1)
Protein Name(s)	Cytochrome c oxidase subunit 1 (ECO:0000256 with RuleBase:RU000369)
External Links
UniProt	Q71KK5
EMBL	AF486855 AF486856 AF486857 AF486858 AF486859 AF486860 AF486861 AF486862 AF486863 AF486864 AF486865 AF486866 AF486867 AF486868 AF486869 AF486870 AF486871 AF486872 AF486873 AF486874 DQ207755 DQ207754 DQ268530 DQ334860 EF375877 EF545567 EF545568 EF545569 EF545570 EF545571 EF545572 EF545573 EF545575 EF545577 EF545578 EF545579 EF545580 EF545581 EF545582 EF545583 EF545584 EF545585 EF545586 EF545587 EF545588 EF545589 EF545590 EF545591 EF545592 EF545593 EU117375 FJ236991 FJ236992 FJ236993 FJ236994 FJ236995 FJ236996 FJ236997 FJ236998 FJ236999 FJ237000 FJ237001 FJ237002 FJ237003 GQ220328 GQ220329 GQ351599 JN601066 JN601067 JN601068 JN601069 JN601070 JN601071 JN601074 JN601075 KC250273 KC250274 KC250275 KC493607 KC493608 KC493609 KC493610 KC493611 KC493612 KC505406 KC505407 KC505408 KC505409 KC505410 KC505411 KF472177 KF472178 KF472179 KF569218 KF601700 KF752550 KF888634 KF767443 KF767444 KJ720205 KJ909516 KJ737417 KJ737418 KJ737419 KJ737422 KJ737423 KM073256 KM200762 AB292606 AB298688
RefSeq	NP_008636.1
SMR	Q71KK5
GeneID	808503
KEGG	ssc:808503
CTD	4512
GeneTree	ENSGT00390000001518
HOVERGEN	HBG003841
KO	K02256
OMA	FHGLASM
GO	GO:0016021 GO:0005751 GO:0004129 GO:0020037 GO:0005506 GO:0009060 GO:0006119
Gene3D	1.20.210.10
InterPro	IPR000883 IPR023615 IPR023616
PANTHER	PTHR10422
Pfam	PF00115
PRINTS	PR01165
SUPFAM	SSF81442
PROSITE	PS50855 PS00077

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
Contributes to	GO:0004129	cytochrome-c oxidase activity	PMID:25646428^[1]	ECO:0000314			F	inner membrane of mitochondria, catalyzes oxygen to water and couples the free energy by pumping protons across the membrane which aids in synthesizing ATP	complete CACAO 10565
involved_in	GO:0045907	positive regulation of vasoconstriction	PMID:24506284^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0022900	electron transport chain	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:0022900	electron transport chain	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:0022900	electron transport chain	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:0022900	electron transport chain	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:1902600	proton transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:1902600	proton transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:1902600	proton transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
involved_in	GO:1902600	proton transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004129	P	Seeded From UniProt	complete
part_of	GO:0045277	respiratory chain complex IV	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00395 ensembl:ENSP00000354499	C	Seeded From UniProt	complete
part_of	GO:0005751	mitochondrial respiratory chain complex IV	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00395 ensembl:ENSP00000354499	C	Seeded From UniProt	complete
part_of	GO:0005750	mitochondrial respiratory chain complex III	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00395 ensembl:ENSP00000354499	C	Seeded From UniProt	complete
enables	GO:0004129	cytochrome-c oxidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00395 ensembl:ENSP00000354499	F	Seeded From UniProt	complete
part_of	GO:0005751	mitochondrial respiratory chain complex IV	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00397 ensembl:ENSMUSP00000080993	C	Seeded From UniProt	complete
part_of	GO:0005743	mitochondrial inner membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00397 ensembl:ENSMUSP00000080993	C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00397 ensembl:ENSMUSP00000080993	C	Seeded From UniProt	complete
enables	GO:0004129	cytochrome-c oxidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P00397 ensembl:ENSMUSP00000080993	F	Seeded From UniProt	complete
enables	GO:0004129	cytochrome-c oxidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000883 InterPro:IPR023615 InterPro:IPR023616	F	Seeded From UniProt	complete
involved_in	GO:0009060	aerobic respiration	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000883	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000883	C	Seeded From UniProt	complete
enables	GO:0020037	heme binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000883	F	Seeded From UniProt	complete
part_of	GO:0045277	respiratory chain complex IV	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033944	C	Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000883 InterPro:IPR023615 InterPro:IPR023616 InterPro:IPR036927	P	Seeded From UniProt	complete
enables	GO:0004129	cytochrome-c oxidase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.9.3.1	F	Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0070469	respirasome	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0679	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0496	C	Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P	Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0249	P	Seeded From UniProt	complete
part_of	GO:0005743	mitochondrial inner membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0999	C	Seeded From UniProt	complete
part_of	GO:0005743	mitochondrial inner membrane	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0168	C	Seeded From UniProt	complete
involved_in	GO:0006119	oxidative phosphorylation	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00705	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Sharma, V et al. (2015) Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase. Proc. Natl. Acad. Sci. U.S.A. 112 2040-5 PubMed GONUTS page
↑ El-Daly, M et al. (2014) Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways. Br. J. Pharmacol. 171 2413-25 PubMed GONUTS page

[PMID:25646428-1] Sharma, V et al. (2015) Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase. Proc. Natl. Acad. Sci. U.S.A. 112 2040-5 PubMed GONUTS page

[PMID:24506284-2] El-Daly, M et al. (2014) Proteinase-activated receptors 1 and 2 and the regulation of porcine coronary artery contractility: a role for distinct tyrosine kinase pathways. Br. J. Pharmacol. 171 2413-25 PubMed GONUTS page

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PIG:Q71KK5

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