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User:Re827609

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Spring 2012 Open Competition

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableBACSU:ERA2012-04-01 16:34:30 CDTGO:0051781 positive regulation of cell division (P)PMID:12399511ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2A is a micrograph image showing normal B. subtilis strain BR151. The cells are short with condensed nucleoids. Figure 2B is a micrograph image showing a Bex null mutant SL7968. The cells are elongated chains with diffuse nucleoids. This is implicates that Bex has a positive role in cell division, more specifically, cell cycle cytokinesis.

challenge
acceptableBACSU:ERA2012-04-01 17:15:14 CDTGO:0032297 negative regulation of DNA-dependent DNA replication initiation (P)PMID:12427945ECO:0000314 direct assay evidence used in manual assertion

Figure 6B shows that the absence of Bex shifts the number of replication origins from 2-4 to 4+ in presence of IPTG. This is evidence that the absence of Bex increases initiation of chromosome replication.

challenge
acceptableBACSU:YQEH2012-04-01 17:18:59 CDTGO:0032297 negative regulation of DNA-dependent DNA replication initiation (P)PMID:12427945ECO:0000314 direct assay evidence used in manual assertion

Figure 6B shows that the absence of YqueH shifts the number of replication origins from 2-4 to 4+ in presence of IPTG. This is evidence that the absence of YqueH increases initiation of chromosome replication.

challenge

acceptable:3
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Re827609

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
requireschangesCbhatt,
Team North Texas
?GO:0030073 - insulin secretion (Figure 5)PMID:12509515IEP: Inferred from Expression Pattern challengeC: 1
requireschangesHughe017,
Team The Histones
HUMAN:UTP6GO:0015935 - small ribosomal subunit (C)PMID:22434888ECO:0000270 expression pattern evidence used in manual assertionchallengeC: 2
requireschangesKr004966,
Team Francis Crick
ECOLX:SULAGO:0032466 - negative regulation of cytokinesis (P)PMID:22432817ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

0 annotations fixed by Re827609


Internal Competition only involving UCF students

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableECOLI:ERA2012-02-24 07:58:09 CSTGO:0003924 GTPase activity (F)PMID:2105934ECO:0000314 direct assay evidence used in manual assertion

Figure 8A. shows that soluble forms of Era, when coupled with GTP, yield both GTP and GDP. This is evidence of GTPase activity.

challenge
acceptableECOLI:ERA2012-02-24 09:05:00 CSTGO:0005886 plasma membrane (C)PMID:8282709ECO:0000314 direct assay evidence used in manual assertion

Figure 5A. shows results of an Era Binding Assay. Era binds to subfractions of the membrane. This is also evidence of Era's presence in the membrane.

challenge

acceptable:2
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Re827609

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Re827609