PMID:12399511

Citation	Minkovsky, N, Zarimani, A, Chary, VK, Johnstone, BH, Powell, BS, Torrance, PD, Court, DL, Simons, RW and Piggot, PJ (2002) Bex, the Bacillus subtilis homolog of the essential Escherichia coli GTPase Era, is required for normal cell division and spore formation. J. Bacteriol. 184:6389-94
Abstract	The Bacillus subtilis bex gene complemented the defect in an Escherichia coli era mutant. The Bex protein showed 39 percent identity and 67 percent similarity to the E. coli Era GTPase. In contrast to era, bex was not essential in all strains. bex mutant cells were elongated and filled with diffuse nucleoid material. They grew slowly and exhibited severely impaired spore formation.
Links	PubMed PMC151948
Keywords	Bacillus subtilis/genetics; Bacillus subtilis/growth & development; Bacillus subtilis/physiology; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cell Division; Culture Media; Escherichia coli/genetics; Escherichia coli Proteins; GTP Phosphohydrolases/genetics; GTP Phosphohydrolases/metabolism; GTP-Binding Proteins/genetics; GTP-Binding Proteins/metabolism; Gene Deletion; Genes, Essential; RNA-Binding Proteins; Sequence Homology; Spores, Bacterial/physiology
edit table

Annotations

Gene product	Qualifier	GO Term	Evidence Code	with/from	Aspect	Extension	Notes	Status
BACSU:ERA	involved_in	GO:0051781: positive regulation of cell division	ECO:0000315: mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
BACSU:ERA		GO:0051781: positive regulation of cell division	ECO:0000315:		P		Figure 2A is a micrograph image showing normal B. subtilis strain BR151. The cells are short with condensed nucleoids. Figure 2B is a micrograph image showing a Bex null mutant SL7968. The cells are elongated chains with diffuse nucleoids. This is implicates that Bex has a positive role in cell division, more specifically, cell cycle cytokinesis.	complete CACAO 4220

References

See Help:References for how to manage references in GONUTS.