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HUMAN:UTP6

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) UTP6 (synonyms: C17orf40, HCA66, MHAT)
Protein Name(s) U3 small nucleolar RNA-associated protein 6 homolog

Hepatocellular carcinoma-associated antigen 66 Multiple hat domains protein

External Links
UniProt Q9NYH9
EMBL AF244135
AF334386
BC015454
BC035325
AJ272197
CCDS CCDS11269.1
RefSeq NP_060898.2
UniGene Hs.589862
ProteinModelPortal Q9NYH9
BioGrid 120923
IntAct Q9NYH9
MINT MINT-1435439
STRING 9606.ENSP00000261708
PhosphoSite Q9NYH9
DMDM 134047946
SWISS-2DPAGE Q9NYH9
MaxQB Q9NYH9
PaxDb Q9NYH9
PRIDE Q9NYH9
Ensembl ENST00000261708
GeneID 55813
KEGG hsa:55813
UCSC uc002hgq.3
CTD 55813
GeneCards GC17M030187
HGNC HGNC:18279
HPA HPA025936
HPA055806
neXtProt NX_Q9NYH9
PharmGKB PA142672224
eggNOG COG5191
GeneTree ENSGT00390000016493
HOGENOM HOG000285956
HOVERGEN HBG051886
InParanoid Q9NYH9
KO K14557
OMA SEDYWDW
OrthoDB EOG7FR7FZ
PhylomeDB Q9NYH9
TreeFam TF323957
ChiTaRS UTP6
GeneWiki UTP6
GenomeRNAi 55813
NextBio 60986
PRO PR:Q9NYH9
Proteomes UP000005640
Bgee Q9NYH9
CleanEx HS_UTP6
ExpressionAtlas Q9NYH9
Genevestigator Q9NYH9
GO GO:0005730
GO:0006364
Gene3D 1.25.40.10
InterPro IPR003107
IPR011990
IPR013949
Pfam PF08640
SMART SM00386

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015935

small ribosomal subunit

PMID:22434888[1]

ECO:0000270

C

Fig. 1,2,3

complete
CACAO 4229

GO:0046601

positive regulation of centriole replication

PMID:22434888[1]

ECO:0000270

P

Fig. 7

complete
CACAO 4230

part_of

GO:0034388

Pwp2p-containing subcomplex of 90S preribosome

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588427
SGD:S000002857

C

Seeded From UniProt

complete

part_of

GO:0032040

small-subunit processome

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588427
SGD:S000002857

C

Seeded From UniProt

complete

involved_in

GO:0000462

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000588427
SGD:S000002857

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000462

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013949

P

Seeded From UniProt

complete

involved_in

GO:0006396

RNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003107

P

Seeded From UniProt

complete

enables

GO:0030515

snoRNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013949

F

Seeded From UniProt

complete

involved_in

GO:0006364

rRNA processing

Reactome:R-HSA-6791226

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-6791228
Reactome:R-HSA-6791227
Reactome:R-HSA-6791222
Reactome:R-HSA-6791221

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

involved_in

GO:0006364

rRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0698

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0188

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bonnart, C et al. (2012) Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplication. Nucleic Acids Res. 40 6270-89 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page