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User:Placekje

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorMOUSE:CAN72013-04-11 12:25:17 CDTGO:0006508 proteolysis (P)PMID:14981075ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 shows identification of 2 calpain cleavage sites by deletion mutagenesis in the Htt protein. This paper suggests that calpains play a role in Htt proteolysis and HD pathology.

challenge

acceptable:0
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Placekje

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
updatedbyinstructorAmchugh,
Team Let's Take This Outside
HUMAN:CHK1GO:0004672 - protein kinase activity (F)PMID:22024163ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2

fixed by Placekje
requireschangesSinghpr4,
Team The Monstars
9GAMM:C8YX85GO:1902087 - dimethylsulfoniopropionate catabolic process (P)PMID:19807777ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
requireschangesJacob.bowman,
Team Ribosome
HUMAN:B5MCN0GO:0044432 - obsolete endoplasmic reticulum part (C)PMID:18270207ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3

1 annotations fixed by Placekje

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