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Category:Team Ribosome

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:ACTSSofia.saari, Team Ribosome2013-04-14 15:57:43 CDTGO:0005200 structural constituent of cytoskeleton (F)PMID:11823199ECO:0000304 author statement supported by traceable reference used in manual assertion

Autodiagram in figure 2 shows strains in food containing ActA are broader.

challenge
requireschangesHUMAN:B5MCN0Jacob.bowman, Team Ribosome2013-04-14 11:49:42 CDTGO:0005794 Golgi apparatus (C)PMID:18270207ECO:0000314 direct assay evidence used in manual assertion

Figure 4 shows tagged atlastin-2 in the Golgi apparatus.

challenge
requireschangesHUMAN:B5MCN0Jacob.bowman, Team Ribosome2013-04-14 11:21:59 CDTGO:0044432 endoplasmic reticulum part (C)PMID:18270207ECO:0000314 direct assay evidence used in manual assertion

Figure 4 shows tagged atlastin-2 localized in the endoplasmic reticulum.

challenge
acceptableHUMAN:H0Y3A8Jacob.bowman, Team Ribosome2013-04-14 11:08:22 CDTGO:0005768 endosome (C)PMID:20573900ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows localization of astrotactin 2 in the endosome with endosomal markers.

challenge
requireschangesHUMAN:F5H1A7Jacob.bowman, Team Ribosome2013-04-14 10:28:40 CDTGO:0005912 adherens junction (C)PMID:22467863ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 shows that depletion of radixin increases adherens junctions which suggests that radixin has a role in this process.

challenge
requireschangesHUMAN:F5H1A7Jacob.bowman, Team Ribosome2013-04-14 10:03:50 CDTGO:0016477 cell migration (P)PMID:22467863ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 suggests that depleting radixin decreases cell migration and increases cell area.

challenge
requireschangesHUMAN:B4DP05Jacob.bowman, Team Ribosome2013-04-13 22:47:54 CDTGO:0006473 protein acetylation (P)PMID:23110170ECO:0000250 sequence similarity evidence used in manual assertion

Figure 4 shows acetylation of microtubules with formin derivatives. Formin-2's role in acetylation is assumed from this data.

challenge
acceptableHUMAN:ONCMRonald.smith, Team Ribosome2013-04-10 19:00:06 CDTGO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein (P)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 6 - OsM shows positive regulation of STAT3 phosphorylation.

challenge
acceptableHUMAN:CTF1Ronald.smith, Team Ribosome2013-04-10 18:58:35 CDTGO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein (P)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 6 - shows CT1 positive regulation of STAT3 phosphorylation.

challenge
acceptableHUMAN:CNTFRonald.smith, Team Ribosome2013-04-10 18:55:24 CDTGO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein (P)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 6 - shows CNTF positive regulation of STAT3 phosphorylation.

challenge
acceptableHUMAN:Q13514Ronald.smith, Team Ribosome2013-04-10 18:52:05 CDTGO:0016324 apical plasma membrane (C)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 5 - gp130 is normally found in apical membrane.

challenge
acceptableHUMAN:OSMRRonald.smith, Team Ribosome2013-04-10 18:47:40 CDTGO:0016324 apical plasma membrane (C)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 5 - OsMRβ normally in the apical membrane

challenge
acceptableHUMAN:CNTFRRonald.smith, Team Ribosome2013-04-10 18:41:20 CDTGO:0016324 apical plasma membrane (C)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 5 - CNTFR normally in the apical membrane.

challenge
correctedthroughchallengesHUMAN:CNTFRonald.smith, Team Ribosome2013-04-09 23:47:49 CDTGO:0003406 retinal pigment epithelium development (P)PMID:21912637ECO:0000314 direct assay evidence used in manual assertion

Figure 4 - states Constitutive expression of CNTF in human RPE.

challenge
requireschangesMOUSE:BTKRonald.smith, Team Ribosome2013-04-09 23:35:06 CDTGO:0033625 positive regulation of integrin activation (P)PMID:20167705ECO:0000314 direct assay evidence used in manual assertion

Figure 1 - The Tec family kinase Btk is required for E-selectin–mediated slow rolling (integrin activation)

challenge
updatedbyinstructorMOUSE:THICRonald.smith, Team Ribosome2013-04-09 23:06:42 CDTGO:0045797 positive regulation of intestinal cholesterol absorption (P)PMID:22045928ECO:0000314 direct assay evidence used in manual assertion

Fig 4

challenge
updatedbyinstructorHUMAN:D6RJD2Jacob.bowman, Team Ribosome2013-04-09 11:59:04 CDTGO:0009986 cell surface (C)PMID:23226524ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 2.

challenge
correctedthroughchallengesHUMAN:MK01Ronald.smith, Team Ribosome2013-04-09 11:51:18 CDTGO:1901202 negative regulation of extracellular matrix assembly (P)PMID:23118220ECO:0000314 direct assay evidence used in manual assertion

Figure 2-RSK2 inhibits fibronectin matrix assembly

challenge
correctedthroughchallengesHUMAN:MK01Ronald.smith, Team Ribosome2013-04-09 11:49:26 CDTGO:0033629 negative regulation of cell adhesion mediated by integrin (P)PMID:23118220ECO:0000314 direct assay evidence used in manual assertion

Figure 2 - RSK2 inhibits integrin activation and impairs cell adhesion

challenge
correctedthroughchallengesHUMAN:MK01Ronald.smith, Team Ribosome2013-04-09 11:47:36 CDTGO:0007162 negative regulation of cell adhesion (P)PMID:23118220ECO:0000314 direct assay evidence used in manual assertion

Figure 1 - RSK2 inhibits integrin activation and impairs cell adhesion.

challenge
correctedthroughchallengesHUMAN:MK01Ronald.smith, Team Ribosome2013-04-09 11:42:45 CDTGO:0033624 negative regulation of integrin activation (P)PMID:23118220ECO:0000314 direct assay evidence used in manual assertion

Figure 1 - RSK2 inhibits integrin activation

challenge
updatedbyinstructorMOUSE:BTKRonald.smith, Team Ribosome2013-04-08 23:06:24 CDTGO:0001818 negative regulation of cytokine production (P)PMID:23544144ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 - Btk regulates cytokine production thus activating an immune response.

challenge

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Pages in category "Team Ribosome"

The following 4 pages are in this category, out of 4 total.


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