MOUSE:CAN7

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Capn7 (synonyms: Palbh)
Protein Name(s)	Calpain-7 PalB homolog PalBH
External Links
UniProt	Q9R1S8
EMBL	AB028640 AJ012475
CCDS	CCDS26911.1
RefSeq	NP_033926.1
UniGene	Mm.201535
ProteinModelPortal	Q9R1S8
SMR	Q9R1S8
STRING	10090.ENSMUSP00000022451
MEROPS	C02.028
PhosphoSite	Q9R1S8
MaxQB	Q9R1S8
PaxDb	Q9R1S8
PRIDE	Q9R1S8
Ensembl	ENSMUST00000022451
GeneID	12339
KEGG	mmu:12339
UCSC	uc007sxm.1
CTD	23473
MGI	MGI:1338030
eggNOG	NOG277123
GeneTree	ENSGT00750000117668
HOGENOM	HOG000006940
HOVERGEN	HBG036832
InParanoid	Q9R1S8
KO	K08576
OMA	SRWVRPD
OrthoDB	EOG7PK8Z7
PhylomeDB	Q9R1S8
TreeFam	TF322245
NextBio	280964
PRO	PR:Q9R1S8
Proteomes	UP000000589
Bgee	Q9R1S8
CleanEx	MM_CAPN7
ExpressionAtlas	Q9R1S8
Genevestigator	Q9R1S8
GO	GO:0005737 GO:0070062 GO:0005634 GO:0004198 GO:0010634 GO:0006508 GO:0097264
Gene3D	1.20.58.280
InterPro	IPR022684 IPR022682 IPR022683 IPR007330 IPR001300
Pfam	PF01067 PF04212 PF00648
PRINTS	PR00704
SMART	SM00720 SM00230 SM00745
SUPFAM	SSF116846 SSF49758
PROSITE	PS50203

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006508	proteolysis	PMID:14981075	ECO:0000315			P		Figure 1 shows identification of 2 calpain cleavage sites by deletion mutagenesis in the Htt protein. This paper suggests that calpains play a role in Htt proteolysis and HD pathology.	complete CACAO 7654
involved_in	GO:0006508	proteolysis	PMID:14981075	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0097264	self proteolysis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9Y6W3	P		Seeded From UniProt	complete
enables	GO:0090541	MIT domain binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9Y6W3	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010634	positive regulation of epithelial cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9Y6W3	P		Seeded From UniProt	complete
enables	GO:0004175	endopeptidase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9Y6W3	F		Seeded From UniProt	complete
involved_in	GO:0097264	self proteolysis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y6W3 ensembl:ENSP00000253693	P		Seeded From UniProt	complete
enables	GO:0090541	MIT domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y6W3 ensembl:ENSP00000253693	F		Seeded From UniProt	complete
involved_in	GO:0010634	positive regulation of epithelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y6W3 ensembl:ENSP00000253693	P		Seeded From UniProt	complete
enables	GO:0004175	endopeptidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y6W3 ensembl:ENSP00000253693	F		Seeded From UniProt	complete
enables	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001300 InterPro:IPR022684	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001300 InterPro:IPR022684	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
enables	GO:0008234	cysteine-type peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0788	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
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References

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