GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
CACAO Fall 2014
|Status||Page||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|HUMAN:AKTS1||2014-09-27 21:08:58 CDT||GO:0038202 TORC1 signaling (P)||PMID:17386266||ECO:0000314 direct assay evidence used in manual assertion|
Section beginning pg 904 for experimental design, Figure 3 (E) shows binding to raptor component of TORC 1
|HUMAN:AKTS1||2014-09-27 21:08:58 CDT||GO:0032868 response to insulin (P)||PMID:17386266||ECO:0000314 direct assay evidence used in manual assertion|
Figure 3 (B) shows insulin regulated
|MOUSE:PIM1||2014-10-11 10:47:25 CDT||GO:1902033 regulation of hematopoietic stem cell proliferation (P)||PMID:23495171||ECO:0000314 direct assay evidence used in manual assertion|
Figure 5 shows enhanced hematopoietic stem cell proliferation with Pim1 is overexpressed. Figure 5 (B) shows decreased proliferation when Pim1 is knocked out.
|MOUSE:PITX1||2014-10-11 11:11:34 CDT||GO:0060415 muscle tissue morphogenesis (P)||PMID:22071103||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 3 (C and D) show that extensor digitorum brevis muscle formation is rescued by Pitx1 but not Tbx4
|MOUSE:PITX1||2014-10-11 11:41:30 CDT||GO:0035116 embryonic hindlimb morphogenesis (P)||PMID:22071103||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 4 (B) shows that when Pitx1 is knocked out, peroneus longus muscle and tendon are absent. Discussion in article notes these findings are due to improper skeletal structure development. In addition, it is inferred from discussion that the entire hindlimb is affected.
|XENLA:Q9DG48||2014-11-23 16:56:07 CST||GO:0048048 embryonic eye morphogenesis (P)||PMID:23874955||ECO:0000315 mutant phenotype evidence used in manual assertion|
Annotations challenged by Macie002
|Status||Author,Group||Page||GO Term (Aspect)||Reference||Evidence||Links||Page history|
|RAT:RNF34||GO:0061630 - ubiquitin protein ligase activity (F)||PMID:25193658||ECO:0000314 direct assay evidence used in manual assertion||challenge||C: 1|
fixed by Macie002
1 annotations fixed by Macie002