User:Macie002

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	HUMAN:AKTS1	2014-09-27 21:08:58 CDT	GO:0038202 TORC1 signaling (P)	PMID:17386266	ECO:0000314 direct assay evidence used in manual assertion	Section beginning pg 904 for experimental design, Figure 3 (E) shows binding to raptor component of TORC 1	challenge
unacceptable	HUMAN:AKTS1	2014-09-27 21:08:58 CDT	GO:0032868 response to insulin (P)	PMID:17386266	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 (B) shows insulin regulated	challenge
acceptable	MOUSE:PIM1	2014-10-11 10:47:25 CDT	GO:1902033 regulation of hematopoietic stem cell proliferation (P)	PMID:23495171	ECO:0000314 direct assay evidence used in manual assertion	Figure 5 shows enhanced hematopoietic stem cell proliferation with Pim1 is overexpressed. Figure 5 (B) shows decreased proliferation when Pim1 is knocked out.	challenge
requireschanges	MOUSE:PITX1	2014-10-11 11:11:34 CDT	GO:0060415 muscle tissue morphogenesis (P)	PMID:22071103	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3 (C and D) show that extensor digitorum brevis muscle formation is rescued by Pitx1 but not Tbx4	challenge
acceptable	MOUSE:PITX1	2014-10-11 11:41:30 CDT	GO:0035116 embryonic hindlimb morphogenesis (P)	PMID:22071103	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 (B) shows that when Pitx1 is knocked out, peroneus longus muscle and tendon are absent. Discussion in article notes these findings are due to improper skeletal structure development. In addition, it is inferred from discussion that the entire hindlimb is affected.	challenge
updatedbyinstructor	XENLA:Q9DG48	2014-11-23 16:56:07 CST	GO:0048048 embryonic eye morphogenesis (P)	PMID:23874955	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2A	challenge

acceptable:2
unacceptable:2
requires_changes:1
flagged:0

Annotations challenged by Macie002

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	JMJ, Team RNA	RAT:RNF34	GO:0061630 - ubiquitin protein ligase activity (F)	PMID:25193658	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1 fixed by Macie002

1 annotations fixed by Macie002

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