GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:Team A-squared

From GONUTS
Jump to: navigation, search
StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorXENLA:Q9DG48Macie002, Team A-squared2014-11-23 16:56:07 CSTGO:0048048 embryonic eye morphogenesis (P)PMID:23874955ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2A

challenge
updatedbyinstructorDROME:MTNDLukas009, Team A-squared2014-11-22 11:42:29 CSTGO:2000243 positive regulation of reproductive process (P)PMID:25037729ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2a: when flies receive poor nutrition wildtype expressing Dadi1 are more fecund, Figure 2b/c: when Dadi1 introduced to flies not expressing Dadi1, fertility increases

challenge
updatedbyinstructorDROME:MTNDLukas009, Team A-squared2014-11-22 11:35:20 CSTGO:0009086 methionine biosynthetic process (P)PMID:25037729ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5-comparing metabolites produced in wildtype to metabolites produced in Dadi1 mutant.

challenge
unacceptable?Lukas009, Team A-squared2014-11-22 11:06:03 CSTGO:0019509 L-methionine biosynthetic process from methylthioadenosine (Figure 3: Knockdown of APIP depletes intracellular levels of methionine.)PMID:23285211IDA: Inferred from Direct Assay
challenge
updatedbyinstructorKLEPN:TYRBLukas009, Team A-squared2014-11-22 10:37:23 CSTGO:0019509 L-methionine biosynthetic process from methylthioadenosine (P)PMID:10074065ECO:0000314 direct assay evidence used in manual assertion

Table 1

challenge
unacceptableKLEPN:TYRBLukas009, Team A-squared2014-11-22 09:56:09 CSTGO:0047297 asparagine-oxo-acid transaminase activity (F)PMID:22569339ECO:0000314 direct assay evidence used in manual assertion

Figure 4A, right side

challenge
acceptableMOUSE:PITX1Macie002, Team A-squared2014-10-11 11:41:30 CDTGO:0035116 embryonic hindlimb morphogenesis (P)PMID:22071103ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4 (B) shows that when Pitx1 is knocked out, peroneus longus muscle and tendon are absent. Discussion in article notes these findings are due to improper skeletal structure development. In addition, it is inferred from discussion that the entire hindlimb is affected.

challenge
requireschangesMOUSE:PITX1Macie002, Team A-squared2014-10-11 11:11:34 CDTGO:0060415 muscle tissue morphogenesis (P)PMID:22071103ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 (C and D) show that extensor digitorum brevis muscle formation is rescued by Pitx1 but not Tbx4

challenge
acceptableMOUSE:PIM1Macie002, Team A-squared2014-10-11 10:47:25 CDTGO:1902033 regulation of hematopoietic stem cell proliferation (P)PMID:23495171ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows enhanced hematopoietic stem cell proliferation with Pim1 is overexpressed. Figure 5 (B) shows decreased proliferation when Pim1 is knocked out.

challenge
unacceptableHUMAN:AKTS1Macie002, Team A-squared2014-09-27 21:08:58 CDTGO:0038202 TORC1 signaling (P)PMID:17386266ECO:0000314 direct assay evidence used in manual assertion

Section beginning pg 904 for experimental design, Figure 3 (E) shows binding to raptor component of TORC 1

challenge
unacceptableHUMAN:AKTS1Macie002, Team A-squared2014-09-27 21:08:58 CDTGO:0032868 response to insulin (P)PMID:17386266ECO:0000314 direct assay evidence used in manual assertion

Figure 3 (B) shows insulin regulated

challenge

What do the icons mean in the status column?

assessment icons.jpg

Pages in category "Team A-squared"

The following 2 pages are in this category, out of 2 total.


Jump to pages starting with: L M