HUMAN:AKTS1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	AKT1S1 (ECO:0000312 with EMBL:AAH16043.1)
Protein Name(s)	Proline-rich AKT1 substrate 1 40 kDa proline-rich AKT substrate
External Links
UniProt	Q96B36
EMBL	AK055511 AK092610 AK316603 AK226004 AC118341 CH471177 CH471177 BC000031 BC007416 BC015562 BC016043 BC051844
CCDS	CCDS12784.1 CCDS59410.1
RefSeq	NP_001092102.1 NP_001092103.1 NP_001265088.1 NP_001265089.1 NP_115751.3
UniGene	Hs.515542 Hs.610819
ProteinModelPortal	Q96B36
BioGrid	124059
IntAct	Q96B36
MINT	MINT-3317903
STRING	9606.ENSP00000341698
BindingDB	Q96B36
ChEMBL	CHEMBL1255161
PhosphoSite	Q96B36
DMDM	74731194
MaxQB	Q96B36
PaxDb	Q96B36
PRIDE	Q96B36
Ensembl	ENST00000344175 ENST00000391831 ENST00000391832 ENST00000391833 ENST00000391834 ENST00000391835
GeneID	84335
KEGG	hsa:84335
UCSC	uc002pql.5 uc002pqm.5
CTD	84335
GeneCards	GC19M050372
HGNC	HGNC:28426
HPA	CAB021903 HPA043590
MIM	610221
neXtProt	NX_Q96B36
PharmGKB	PA134943587
eggNOG	NOG40718
GeneTree	ENSGT00390000017397
HOVERGEN	HBG059465
InParanoid	Q96B36
KO	K16184
OMA	LFMMDED
OrthoDB	EOG7X3QRW
PhylomeDB	Q96B36
Reactome	REACT_12564 REACT_147727 REACT_200775
SignaLink	Q96B36
ChiTaRS	AKT1S1
GeneWiki	AKT1S1
GenomeRNAi	84335
NextBio	35535165
PRO	PR:Q96B36
Proteomes	UP000005640
Bgee	Q96B36
CleanEx	HS_AKT1S1
ExpressionAtlas	Q96B36
Genevestigator	Q96B36
GO	GO:0005737 GO:0005829 GO:0005634 GO:0043234 GO:0007173 GO:0038095 GO:0008543 GO:0045087 GO:0045792 GO:0006469 GO:0032007 GO:0048011 GO:0048015 GO:0043523
InterPro	IPR026682
PANTHER	PTHR21844

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0038202	TORC1 signaling	PMID:17386266	ECO:0000314			P		Section beginning pg 904 for experimental design, Figure 3 (E) shows binding to raptor component of TORC 1	complete CACAO 10148
	GO:0032868	response to insulin	PMID:17386266	ECO:0000314			P		Figure 3 (B) shows insulin regulated	complete CACAO 10149
involved_in	GO:0042981	regulation of apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9D1F4	P		Seeded From UniProt	complete
involved_in	GO:0045792	negative regulation of cell size	PMID:17386266	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043523	regulation of neuron apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9D1F4	P		Seeded From UniProt	complete
involved_in	GO:0032007	negative regulation of TOR signaling	PMID:17386266	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
colocalizes_with	GO:0031931	TORC1 complex	PMID:17386266	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006469	negative regulation of protein kinase activity	PMID:17386266	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9D1F4	C		Seeded From UniProt	complete
involved_in	GO:0032007	negative regulation of TOR signaling		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0267824 PANTHER:PTN001094901 UniProtKB:Q96B36	P		Seeded From UniProt	complete
part_of	GO:0031931	TORC1 complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001094901 UniProtKB:Q96B36	C		Seeded From UniProt	complete
involved_in	GO:0006469	negative regulation of protein kinase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001094901 UniProtKB:Q96B36	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001094901 RGD:1312049	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZH75 ensembl:ENSRNOP00000027478	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZH75 ensembl:ENSRNOP00000027478	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3ZH75 ensembl:ENSRNOP00000027478	C		Seeded From UniProt	complete
involved_in	GO:0032007	negative regulation of TOR signaling	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026682	P		Seeded From UniProt	complete
involved_in	GO:0048011	neurotrophin TRK receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026682	P		Seeded From UniProt	complete
involved_in	GO:1900034	regulation of cellular response to heat	Reactome:R-HSA-3371571	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-5672843 Reactome:R-HSA-5672828 Reactome:R-HSA-5672824 Reactome:R-HSA-377186 Reactome:R-HSA-2399977 Reactome:R-HSA-200143	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-5082405	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0091	C		Seeded From UniProt	complete
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References

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