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RAT:RNF34

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Rnf34 (ECO:0000312 with RGD:628636)
Protein Name(s) E3 ubiquitin-protein ligase RNF34 (ECO:0000305)

RING finger protein 34 (ECO:0000312 with RGD:628636) RING finger protein MOMO (ECO:0000303 with PMID:12859687[1])

External Links
UniProt Q6AYH3
EMBL AY157968
BC079044
RefSeq NP_001004075.1
UniGene Rn.14904
ProteinModelPortal Q6AYH3
STRING 10116.ENSRNOP00000001799
PRIDE Q6AYH3
Ensembl ENSRNOT00000001799
GeneID 282845
KEGG rno:282845
UCSC RGD:628636
CTD 80196
RGD 628636
eggNOG NOG121302
GeneTree ENSGT00390000012719
HOGENOM HOG000068080
HOVERGEN HBG055079
InParanoid Q6AYH3
OMA NPDFSTY
OrthoDB EOG70GMFS
PhylomeDB Q6AYH3
TreeFam TF325195
Reactome REACT_199254
UniPathway UPA00143
NextBio 624935
PRO PR:Q6AYH3
Proteomes UP000002494
Genevestigator Q6AYH3
GO GO:0005737
GO:0005829
GO:0012505
GO:0016607
GO:0005634
GO:0005886
GO:0016874
GO:1901981
GO:0061630
GO:0004842
GO:0008270
GO:2001271
GO:1902042
GO:1901797
GO:0035872
GO:0043161
GO:0070936
GO:0016567
GO:0042787
GO:2000374
Gene3D 3.30.40.10
InterPro IPR011011
IPR001841
IPR013083
SMART SM00184
SUPFAM SSF57903
PROSITE PS50089

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0061630

ubiquitin protein ligase activity

PMID:25193658[2]

ECO:0000314

F

Figure 1G

complete
CACAO 10136

enables

GO:0061630

ubiquitin protein ligase activity

PMID:25193658[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006511

ubiquitin-dependent protein catabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

involved_in

GO:2000374

regulation of oxygen metabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q99KR6

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

C

Seeded From UniProt

complete

enables

GO:0061630

ubiquitin protein ligase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

F

Seeded From UniProt

complete

involved_in

GO:1901797

negative regulation of signal transduction by p53 class mediator

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

involved_in

GO:0070936

protein K48-linked ubiquitination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

involved_in

GO:0035872

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

involved_in

GO:2001271

negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

involved_in

GO:1902042

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

enables

GO:1901981

phosphatidylinositol phosphate binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

F

Seeded From UniProt

complete

involved_in

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q969K3

C

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

PMID:12859687[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:2001271

negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

involved_in

GO:1902042

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

enables

GO:1901981

phosphatidylinositol phosphate binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

F

Seeded From UniProt

complete

involved_in

GO:1901797

negative regulation of signal transduction by p53 class mediator

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

involved_in

GO:0070936

protein K48-linked ubiquitination

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

enables

GO:0061630

ubiquitin protein ligase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

F

Seeded From UniProt

complete

involved_in

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

involved_in

GO:0035872

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

enables

GO:0031625

ubiquitin protein ligase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

F

Seeded From UniProt

complete

part_of

GO:0016604

nuclear body

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

C

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

involved_in

GO:0006511

ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

C

Seeded From UniProt

complete

enables

GO:0002039

p53 binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q969K3
ensembl:ENSP00000376258

F

Seeded From UniProt

complete

involved_in

GO:2000374

regulation of oxygen metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR6
ensembl:ENSMUSP00000031434

P

Seeded From UniProt

complete

involved_in

GO:0070417

cellular response to cold

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR6
ensembl:ENSMUSP00000031434

P

Seeded From UniProt

complete

involved_in

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR6
ensembl:ENSMUSP00000031434

P

Seeded From UniProt

complete

involved_in

GO:0006511

ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99KR6
ensembl:ENSMUSP00000031434

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0091

C

Seeded From UniProt

complete

part_of

GO:0012505

endomembrane system

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0147

C

Seeded From UniProt

complete

part_of

GO:0016607

nuclear speck

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0186

C

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00143

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Araki, K et al. (2003) A palmitoylated RING finger ubiquitin ligase and its homologue in the brain membranes. J. Neurochem. 86 749-62 PubMed GONUTS page
  2. 2.0 2.1 Jin, H et al. (2014) Ring finger protein 34 (RNF34) interacts with and promotes γ-aminobutyric acid type-A receptor degradation via ubiquitination of the γ2 subunit. J. Biol. Chem. 289 29420-36 PubMed GONUTS page