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User:Kchiang

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableBORBG:OSPC2013-02-10 04:48:06 CSTGO:0001816 cytokine production (P)PMID:23386602ECO:0000314 direct assay evidence used in manual assertion

Figure 3. Effect of Borrelia burgdorferi on IL-1β production in the presence and absence of autophagy inhibitors.

challenge
requireschangesHUMAN:IL1B2013-02-10 05:17:13 CSTGO:0010628 positive regulation of gene expression (P)PMID:21246541ECO:0000314 direct assay evidence used in manual assertion

Figure 3. Different conditioned supernatants were screened to identify the agent that induced CD1 expression.

challenge
updatedbyinstructorHUMAN:NOD22013-02-10 07:04:31 CSTGO:0002720 positive regulation of cytokine production involved in immune response (P)PMID:20441518ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5. Effectiveness of NOD2 to produce cytokines as an immune response to Borrelia burgdorferi shown through experimentation of stimulated PBMCs.

challenge
updatedbyinstructorBORBU:O517122013-02-10 08:23:25 CSTGO:0044008 dissemination or transmission of symbiont from host by vector (P)PMID:22359504ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4. Images show the negative effects of a lack of RpoS has on spirochetes in the formation of mobile bodies and transmission of symbiont.

challenge

acceptable:0
unacceptable:1
requires_changes:1
flagged:0

Annotations challenged by Kchiang

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableSswiger,
Team Genetic Ninjas
HUMAN:DNLI4GO:0006260 - DNA replication (P)PMID:7760816ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
updatedbyinstructorRgarcia,
Team Chalupa Batman
STAAU:CNAGO:0009274 - peptidoglycan-based cell wall (C)PMID:15181582ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
unacceptableRgarcia,
Team Chalupa Batman
HUMAN:DYH8GO:0030286 - dynein complex (C)PMID:22863569ECO:0000314 direct assay evidence used in manual assertionchallengeC: 5

0 annotations fixed by Kchiang

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