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PMID:15181582
| Citation |
Xu, Y, Rivas, JM, Brown, EL, Liang, X and Höök, M (2004) Virulence potential of the staphylococcal adhesin CNA in experimental arthritis is determined by its affinity for collagen. J. Infect. Dis. 189:2323-33 |
|---|---|
| Abstract |
Staphylococcus aureus is a major cause of bacterial arthritis, which often results in severe joint damage. CNA, a collagen adhesin of S. aureus, was shown to be a virulence factor in several animal models. However, the precise molecular mechanism by which CNA contributes to virulence remains unclear. |
| Links |
PubMed Online version:10.1086/420851 |
| Keywords |
Adhesins, Bacterial/genetics; Adhesins, Bacterial/metabolism; Animals; Arthritis, Experimental/microbiology; Arthritis, Experimental/pathology; Arthritis, Infectious/microbiology; Arthritis, Infectious/pathology; Collagen/metabolism; Female; Humans; Joints/pathology; Mice; Mice, Inbred BALB C; Mutation; Staphylococcal Infections/microbiology; Staphylococcal Infections/pathology; Staphylococcus aureus/pathogenicity; Virulence |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009274: peptidoglycan-based cell wall |
ECO:0000314: |
C |
Fig 3 |
complete | ||||
|
part_of |
GO:0009274: peptidoglycan-based cell wall |
ECO:0000314: direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
See also
References
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