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User:Dlnell

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:HS90B2013-10-10 23:02:22 CDTGO:0016032 viral process (P)PMID:24098578ECO:0000314 direct assay evidence used in manual assertion

Figure 3: RD cells transfected with Hsp90-alpha and Hsp90-beta specific siRNA. Only Hsp90-beta siRNA prevented EV71 capsid protein expression showing Hsp90-beta is involved in EV71 infection

challenge
updatedbyinstructorHUMAN:HDAC12013-10-10 23:37:54 CDTGO:0010629 negative regulation of gene expression (P)PMID:16581785ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3: Acts as a repressor of INF-beta gene expression

challenge
unacceptable9PARA:Q14V372013-11-10 11:57:16 CSTGO:0046718 viral entry into host cell (P)PMID:7853502ECO:0000314 direct assay evidence used in manual assertion

Syncytia only seen in mouse-human hybrid (IL-115) cells when cotransfected with CDV-HA (F protein source not as important, but also required for infection)

challenge
requireschangesCHICK:S5RDP92013-11-10 16:08:40 CSTGO:0051607 defense response to virus (P)PMID:24067955ECO:0000314 direct assay evidence used in manual assertion

Figure 3. Decreased viral infection when IFITM3 present in chicken cells. Figure 4 and 5 also.

challenge

acceptable:0
unacceptable:2
requires_changes:1
flagged:0

Annotations challenged by Dlnell

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
acceptableSabrinamoisan,
Team Go Pro
HUMAN:ZFY27GO:0071782 - endoplasmic reticulum tubular network (C)PMID:23969831ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
unacceptableGyang23,
Team Despicable Us
ECOLI:RECAGO:0003677 - DNA binding (P)PMID:24036048ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
unacceptableKbohning,
Team Bucky's Bugs
PSEAE:LASRGO:0003700 - DNA-binding transcription factor activity (F)PMID:23066081ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3

0 annotations fixed by Dlnell

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