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User:CWilliams2

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CACAO Spring 2017

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableCHICK:Q9PTX12017-04-07 09:17:11 CDTGO:0008283 cell proliferation (P)PMID:21430154ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3b is showing that the pax2 and pax5 are inhibiting supporting cell proliferation while pax3 and pax7 have no significant effect on proliferation.

challenge
unacceptableCHICK:JUND2017-04-07 09:38:50 CDTGO:0070654 sensory epithelium regeneration (P)21430154:21430154ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3A shows Knockdowns of CEBPG and β-catenin significantly reduced SC proliferation, similar to JUND siRNA treatments to promote SE regeneration.

challenge
unacceptableCHICK:Q9W6012017-04-22 23:45:05 CDTGO:0008283 cell proliferation (P)PMID:21430154ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3b is showing that the pax2 and pax5 are inhibiting supporting cell proliferation while pax3 and pax7 have no significant effect on proliferation.

challenge
unacceptableHUMAN:CDK192017-04-23 00:56:21 CDTGO:0008283 cell proliferation (P)PMID:28416637ECO:0000316 genetic interaction evidence used in manual assertion

Expression of CDK8 rescues the proliferation defect in shCDK19 cells treated with Nutlin-3.


challenge
unacceptableHUMAN:CDK82017-04-23 00:59:29 CDTGO:0008283 cell proliferation (P)PMID:28416637ECO:0000316 genetic interaction evidence used in manual assertion

Expression of CDK8 rescues the proliferation defect in shCDK19 cells treated with Nutlin-3.

challenge
updatedbyinstructorYEAST:XRS22017-04-23 10:06:18 CDTGO:0006303 double-strand break repair via nonhomologous end joining (P)PMID:27746018ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 shows Xrs2 is Required for End Joining and Tel1 Signaling Functions of the MRX Complex in Saccharomyces cerevisiae

challenge
unacceptableHUMAN:DNAS12017-04-23 10:42:57 CDTGO:0051179 localization (P)PMID:28185850ECO:0000316 genetic interaction evidence used in manual assertion

In figure 3, detection of DDB2 or XPC protein together with PCNA was significantly enhanced after DNase I digestion, by more than 4 and 5 times, respectively.

challenge
updatedbyinstructorHUMAN:TFDP12017-04-23 11:55:50 CDTGO:0006366 transcription from RNA polymerase II promoter (P)PMID:27825926ECO:0000315 mutant phenotype evidence used in manual assertion

Human. Figure 4. F403A expression vector showed clearly weaker enhancement as compared with the WT expression vector, suggesting that the acidic string of DP1 contributes to E2F1-mediated transcriptional activation.

challenge
unacceptableHUMAN:CDK72017-04-23 16:49:17 CDTGO:0010467 gene expression (P)PMID:27759017ECO:0000315 mutant phenotype evidence used in manual assertion

figure 1 showed T. gondii genes cdk7, cyclinH and mat1 were expressed in the respective transformants as shown by Western blotting using ant-His antibody. S. cerevisiae GAPDH was used as a loading control

challenge

acceptable:0
unacceptable:7
requires_changes:0
flagged:0

Annotations challenged by CWilliams2

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by CWilliams2

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