GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

CHICK:Q9PTX1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) Pax-2 (ECO:0000313 with EMBL:BAA88987.1)
Protein Name(s) Paired-box containing protein Pax-2 (ECO:0000313 with EMBL:BAA88987.1)
External Links
UniProt Q9PTX1
EMBL AB026496
RefSeq NP_990124.1
UniGene Gga.313
ProteinModelPortal Q9PTX1
SMR Q9PTX1
STRING 9031.ENSGALP00000039373
GeneID 395574
KEGG gga:395574
CTD 5076
eggNOG NOG326044
HOGENOM HOG000230938
HOVERGEN HBG009115
KO K15608
PhylomeDB Q9PTX1
NextBio 20815648
GO GO:0005634
GO:0003677
GO:0001071
GO:0060993
GO:0061456
GO:0072179
GO:0072178
GO:2001141
GO:0006355
GO:0006351
Gene3D 1.10.10.10
InterPro IPR009057
IPR001523
IPR022130
IPR011991
Pfam PF00292
PF12403
PRINTS PR00027
SMART SM00351
SUPFAM SSF46689
PROSITE PS00034
PS51057

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008283

cell proliferation

PMID:21430154[1]

ECO:0000315

P

Figure 3b is showing that the pax2 and pax5 are inhibiting supporting cell proliferation while pax3 and pax7 have no significant effect on proliferation.

complete
CACAO 12480

involved_in

GO:0035282

segmentation

PMID:12617855[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001756

somitogenesis

PMID:12617855[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0072179

nephric duct formation

PMID:10021330[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001822

kidney development

PMID:10021330[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035282

segmentation

PMID:14516678[4]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001756

somitogenesis

PMID:14516678[4]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2001141

regulation of RNA biosynthetic process

PMID:12490201[5]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0072179

nephric duct formation

PMID:12490201[5]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0072178

nephric duct morphogenesis

PMID:16790474[6]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061456

mesenchymal stem cell migration involved in uteric bud morphogenesis

PMID:19450546[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060993

kidney morphogenesis

PMID:19450546[7]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12490201[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:2000378

negative regulation of reactive oxygen species metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0072207

metanephric epithelium development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0050679

positive regulation of epithelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0045918

negative regulation of cytolysis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

F

Seeded From UniProt

complete

involved_in

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

involved_in

GO:0035566

regulation of metanephros size

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

part_of

GO:0034451

centriolar satellite

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

C

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

F

Seeded From UniProt

complete

part_of

GO:0005815

microtubule organizing center

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

F

Seeded From UniProt

complete

involved_in

GO:0001658

branching involved in ureteric bud morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

P

Seeded From UniProt

complete

enables

GO:0000987

proximal promoter sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02962
ensembl:ENSP00000359319

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001523
InterPro:IPR009057

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001523

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Alvarado, DM et al. (2011) An RNA interference-based screen of transcription factor genes identifies pathways necessary for sensory regeneration in the avian inner ear. J. Neurosci. 31 4535-43 PubMed GONUTS page
  2. 2.0 2.1 Suetsugu, R et al. (2002) Pax 2 expression in mesodermal segmentation and its relationship with EphA4 and Lunatic-fringe during chicken somitogenesis. Gene Expr. Patterns 2 157-61 PubMed GONUTS page
  3. 3.0 3.1 Obara-Ishihara, T et al. (1999) The surface ectoderm is essential for nephric duct formation in intermediate mesoderm. Development 126 1103-8 PubMed GONUTS page
  4. 4.0 4.1 Suetsugu, R et al. (2002) Pax 2 expression in mesodermal segmentation and its relationship with EphA4 and Lunatic-fringe during chicken somitogenesis. Mech. Dev. 119 Suppl 1 S155-9 PubMed GONUTS page
  5. 5.0 5.1 5.2 James, RG & Schultheiss, TM (2003) Patterning of the avian intermediate mesoderm by lateral plate and axial tissues. Dev. Biol. 253 109-24 PubMed GONUTS page
  6. James, RG et al. (2006) Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells. Development 133 2995-3004 PubMed GONUTS page
  7. 7.0 7.1 Fukui, A et al. (2009) Integration of human mesenchymal stem cells into the Wolffian duct in chicken embryos. Biochem. Biophys. Res. Commun. 385 330-5 PubMed GONUTS page