GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:0019226 | transmission of nerve impulse | PMID:12606764 | IMP: Inferred from Mutant Phenotype | P | ||||
| This annotation made on page: MOUSE:ACHB4 By: Kfree (group Team Bfast Taco) on 2014-01-27 21:02:25 CST. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Csobelman, Team Lobster Soul | 2014-02-09 15:24:41 CST | must be inferred from direct assay, IDA | 0 |
| Challenge | Kfree, Team Bfast Taco | 2014-02-08 19:28:04 CST | GO:0051971 "positive regulation of transmission of nerve impulse" is appropriate. The authors state "the bradycardic effect was significantly attenuated in β4−/− mice." Thus, the subunit must maintain the extent of a nerve pulse. The GO term is defined as "any process that activates, maintains, or increases the frequency, rate or extent of transmission of a nerve impulse..." The evidence code is correct as is. While a direct assay was shown in Fig. 2, the authors use a mutant to compare the function to the wild-type. From the Evidence Code rules page, "If the authors are using mutants to show a difference between alleles, even if the authors are using a direct assay, use IMP." | 5 |
| Challenge | Deasterling, Team Chicken Day | 2014-02-07 23:51:04 CST | The Evidence Code should be inferred from a direct assay because it is a graph showing data collected. The GO Term (GO:0048486) would better explain what is going on in the figure. | 0 |
| Challenge | Aataei, Team BGOW | 2014-02-06 22:07:10 CST | A figure was used and therefore the evidence code should be IDA, inferred from direct assay | 0 |
| Challenge | Druelas, Team BGOW | 2014-02-06 16:04:06 CST | Evidence code needs to be a direct assay. | 0 |
| Private Assessment | Suzialeksander | 2014-05-08 16:13:01 CDT | You need to be an instructor to view these notes. | Updated by Instructor |
| Public Assessment | Suzialeksander | 2014-02-10 15:51:18 CST | oints and annotation credit go to Kfree, who was not only correct but gave a thoughtful defence to the annotation. Not GO:0048486, a development term. | Corrected Through Challenges ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
| Private Assessment | Suzialeksander | 2014-02-10 15:50:06 CST | You need to be an instructor to view these notes. | Corrected Through Challenges ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
| Public Assessment | DanielRenfro | 2014-02-07 23:51:04 CST | This annotation has been flagged because it has been edited since last assessment | Flagged |
| Private Assessment | Suzialeksander | 2014-02-07 14:48:42 CST | You need to be an instructor to view these notes. | Requires Changes ✔ Protein ✔ Publication ✔ Qualifier ✗ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
