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MOUSE:G6PD1
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | G6pdx (synonyms: G6pd, G6pd-1) | |
Protein Name(s) | Glucose-6-phosphate 1-dehydrogenase X
G6PD | |
External Links | ||
UniProt | Q00612 | |
EMBL | Z11911 AK088135 X53617 U88533 U88534 | |
CCDS | CCDS30232.1 | |
PIR | A56686 | |
RefSeq | NP_032088.1 | |
UniGene | Mm.27210 | |
ProteinModelPortal | Q00612 | |
SMR | Q00612 | |
IntAct | Q00612 | |
MINT | MINT-4095477 | |
PhosphoSite | Q00612 | |
REPRODUCTION-2DPAGE | IPI00228385 Q00612 | |
MaxQB | Q00612 | |
PaxDb | Q00612 | |
PRIDE | Q00612 | |
Ensembl | ENSMUST00000004327 | |
GeneID | 14381 | |
KEGG | mmu:14381 | |
UCSC | uc009toy.1 | |
CTD | 14381 | |
MGI | MGI:105979 | |
eggNOG | COG0364 | |
HOGENOM | HOG000046192 | |
HOVERGEN | HBG000856 | |
InParanoid | Q00612 | |
KO | K00036 | |
OMA | HNLQTTK | |
OrthoDB | EOG7DRJ2T | |
PhylomeDB | Q00612 | |
TreeFam | TF300584 | |
Reactome | REACT_246505 | |
UniPathway | UPA00115 | |
NextBio | 285893 | |
PRO | PR:Q00612 | |
Proteomes | UP000000589 | |
Bgee | Q00612 | |
CleanEx | MM_G6PDX | |
ExpressionAtlas | Q00612 | |
Genevestigator | Q00612 | |
GO | GO:0004345 GO:0050661 GO:0042803 GO:0001998 GO:0001816 GO:0048821 GO:0051156 GO:0006749 GO:0032613 GO:0032615 GO:0006741 GO:0006739 GO:0019322 GO:0006098 GO:0040014 GO:0006979 GO:0002033 | |
Gene3D | 3.40.50.720 | |
HAMAP | MF_00966 | |
InterPro | IPR001282 IPR019796 IPR022675 IPR022674 IPR016040 | |
PANTHER | PTHR23429 | |
Pfam | PF02781 PF00479 | |
PIRSF | PIRSF000110 | |
PRINTS | PR00079 | |
TIGRFAMs | TIGR00871 | |
PROSITE | PS00069 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0051156 |
glucose 6-phosphate metabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006739 |
NADP metabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:2000378 |
negative regulation of reactive oxygen species metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1904879 |
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0061052 |
negative regulation of cell growth involved in cardiac muscle cell development |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0055114 |
oxidation-reduction process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0051156 |
glucose 6-phosphate metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0051156 |
glucose 6-phosphate metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0050661 |
NADP binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0050661 |
NADP binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0048821 |
erythrocyte development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0048821 |
erythrocyte development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0046390 |
ribose phosphate biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0045471 |
response to ethanol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043523 |
regulation of neuron apoptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043249 |
erythrocyte maturation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0040014 |
regulation of multicellular organism growth |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0034599 |
cellular response to oxidative stress |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0032615 |
interleukin-12 production |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0032613 |
interleukin-10 production |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0030246 |
carbohydrate binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0019322 |
pentose biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0010734 |
negative regulation of protein glutathionylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0009898 |
cytoplasmic side of plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0009051 |
pentose-phosphate shunt, oxidative branch |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0009051 |
pentose-phosphate shunt, oxidative branch |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387672 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006749 |
glutathione metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2183760 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006749 |
glutathione metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006741 |
NADP biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006740 |
NADPH regeneration |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006739 |
NADP metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006695 |
cholesterol biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005536 |
glucose binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005536 |
glucose binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387672 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(EMAPA:16332) |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2645 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0002033 |
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001998 |
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001816 |
cytokine production |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2182739 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006006 |
glucose metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001282 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0050661 |
NADP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001282 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004345 |
glucose-6-phosphate dehydrogenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0005975 |
carbohydrate metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006006 |
glucose metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00115 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Paglialunga, F et al. (2004) G6PD is indispensable for erythropoiesis after the embryonic-adult hemoglobin switch. Blood 104 3148-52 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Spolarics, Z et al. (2004) Red blood cell dysfunction in septic glucose-6-phosphate dehydrogenase-deficient mice. Am. J. Physiol. Heart Circ. Physiol. 286 H2118-26 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Hendriksen, PJ et al. (1997) Testis-specific expression of a functional retroposon encoding glucose-6-phosphate dehydrogenase in the mouse. Genomics 41 350-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Nicol, CJ et al. (2000) An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis. FASEB J. 14 111-27 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Wilmanski, J et al. (2005) Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages. J. Leukoc. Biol. 78 85-94 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Neifer, S et al. (1991) Characterization of erythrocytic glucose-6-phosphate dehydrogenase in a mouse strain with reduced G6PD activity. Biomed. Biochim. Acta 50 233-8 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 Matsui, R et al. (2005) Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II. Circulation 112 257-63 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Jain, M et al. (2004) Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase. Circulation 109 898-903 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Khan, A et al. (1998) Glucose-6-phosphatase activity in the hypothalamus of the ob/ob mouse. Metab. Clin. Exp. 47 627-9 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Hodge, DL et al. (1998) Structural characterization and tissue-specific expression of the mouse glucose-6-phosphate dehydrogenase gene. DNA Cell Biol. 17 283-91 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Kuraguchi, M et al. (1997) Somatic mutation of the glucose-6-phosphate dehydrogenase (g6pd) gene in colonic stem cells and crypt restricted loss of G6PD activity. Mutat. Res. 379 69-75 PubMed GONUTS page
- ↑ 12.0 12.1 De Schepper, GG et al. (1993) In situ glucose-6-phosphate dehydrogenase activity during development of pre-implantation mouse embryos. Histochem. J. 25 299-303 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Erickson, RP & Harper, K (1980) A major autosomal gene effect on activity of glucose 6-phosphate dehydrogenase segregating between recombinant inbred lines of mice. Genet. Res. 36 91-7 PubMed GONUTS page
- ↑ 14.0 14.1 Pandolfi, PP et al. (1995) Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. EMBO J. 14 5209-15 PubMed GONUTS page
- ↑ 15.0 15.1 Felix, K et al. (2003) Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase. Free Radic. Biol. Med. 34 226-32 PubMed GONUTS page
- ↑ 16.0 16.1 Sanders, S et al. (1997) A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiency. Mutat. Res. 374 79-87 PubMed GONUTS page
- ↑ 17.0 17.1 Pretsch, W et al. (1988) X-linked glucose-6-phosphate dehydrogenase deficiency in Mus musculus. Biochem. Genet. 26 89-103 PubMed GONUTS page
- ↑ Chapman, VM & Shows, TB (1976) Somatic cell genetic evidence for X-chromosome linkage of three enzymes in the mouse. Nature 259 665-7 PubMed GONUTS page
- ↑ Epstein, CJ (1969) Mammalian oocytes: X chromosome activity. Science 163 1078-9 PubMed GONUTS page
- ↑ Peters, J et al. (1988) The localization of G6pd, glucose-6-phosphate dehydrogenase, and mdx, muscular dystrophy in the mouse X chromosome. Genet. Res. 52 195-201 PubMed GONUTS page
- ↑ White, RA et al. (2004) Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse. Blood 104 1511-8 PubMed GONUTS page
a
c
- GO:0005975 ! carbohydrate metabolic process
- GO:0030246 ! carbohydrate binding
- GO:0034599 ! cellular response to oxidative stress
- GO:0006695 ! cholesterol biosynthetic process
- Chordata
- Craniata
- GO:0001816 ! cytokine production
- GO:0005737 ! cytoplasm
- GO:0009898 ! cytoplasmic side of plasma membrane
- GO:0005829 ! cytosol
e
g
i
n
- GO:0006740 ! NADPH regeneration
- GO:0050661 ! NADP binding
- GO:0006741 ! NADP biosynthetic process
- GO:0006739 ! NADP metabolic process
- GO:2000378 ! negative regulation of reactive oxygen species metabolic process
- GO:0061052 ! negative regulation of cell growth involved in cardiac muscle cell development
- GO:0010734 ! negative regulation of protein glutathionylation
- GO:0005634 ! nucleus
p
r