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PMID:5764873

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Citation

Epstein, CJ (1969) Mammalian oocytes: X chromosome activity. Science 163:1078-9

Abstract

The glucose-6-phosphate dehydrogenase and lactate dehydrogenase contents of oocytes from XO and XX female mice have been measured. The activity of the former in the oocytes of XO mice is half of that in the oocytes of XX mice, whereas the lactate dehydrogenase activities in the two groups of ova are the same. These results indicate that glucose-6-phosphate dehydrogenase from a mouse oocyte is an X-linked enzyme, that its synthesis occurs in the oocyte and is dosage dependent, and that inactivation of the X chromosome does not occur in the mouse oocyte.

Links

PubMed

Keywords

Animals; Female; Glucosephosphate Dehydrogenase/analysis; L-Lactate Dehydrogenase/analysis; Male; Mice; Ovum/enzymology; Sex Chromosome Aberrations/enzymology; Sex Chromosomes/enzymology

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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