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MOUSE:DLG4
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Dlg4 (synonyms: Dlgh4, Psd95) | |
Protein Name(s) | Disks large homolog 4
Postsynaptic density protein 95 PSD-95 Synapse-associated protein 90 SAP-90 SAP90 | |
External Links | ||
UniProt | Q62108 | |
EMBL | D50621 AL596185 AL596185 AL596185 BC014807 | |
CCDS | CCDS36202.1 CCDS48829.1 | |
RefSeq | NP_001103222.1 NP_031890.1 | |
UniGene | Mm.27256 | |
ProteinModelPortal | Q62108 | |
SMR | Q62108 | |
BioGrid | 199230 | |
DIP | DIP-29888N | |
IntAct | Q62108 | |
MINT | MINT-136080 | |
ChEMBL | CHEMBL1795134 | |
PhosphoSite | Q62108 | |
MaxQB | Q62108 | |
PaxDb | Q62108 | |
PRIDE | Q62108 | |
Ensembl | ENSMUST00000018700 ENSMUST00000108588 ENSMUST00000108589 | |
GeneID | 13385 | |
KEGG | mmu:13385 | |
UCSC | uc007jtp.2 uc007jtq.2 | |
CTD | 1742 | |
MGI | MGI:1277959 | |
eggNOG | COG0194 | |
GeneTree | ENSGT00760000118866 | |
HOGENOM | HOG000232102 | |
HOVERGEN | HBG107814 | |
InParanoid | Q62108 | |
KO | K11828 | |
OMA | CLEDVMH | |
OrthoDB | EOG79GT6P | |
PhylomeDB | Q62108 | |
TreeFam | TF323171 | |
Reactome | REACT_198244 REACT_198248 REACT_198694 REACT_230679 REACT_258217 | |
ChiTaRS | Dlg4 | |
NextBio | 283740 | |
PRO | PR:Q62108 | |
Proteomes | UP000000589 | |
Bgee | Q62108 | |
CleanEx | MM_DLG4 | |
ExpressionAtlas | Q62108 | |
Genevestigator | Q62108 | |
GO | GO:0032281 GO:0030054 GO:0044300 GO:0030863 GO:0005737 GO:0030425 GO:0032839 GO:0043197 GO:0005783 GO:0060076 GO:0031234 GO:0044224 GO:0016020 GO:0044306 GO:0044309 GO:0097481 GO:0005886 GO:0014069 GO:0045211 GO:0045202 GO:0097060 GO:0008021 GO:0033130 GO:0031697 GO:0031748 GO:0035255 GO:0042043 GO:0031812 GO:0030165 GO:0008022 GO:0032403 GO:0019903 GO:0097110 GO:0005198 GO:0097113 GO:0060997 GO:0045184 GO:0007626 GO:0035641 GO:0002091 GO:0050885 GO:0007204 GO:2000463 GO:0050806 GO:0006461 GO:0035418 GO:0097120 GO:2000821 GO:0048169 GO:2000310 GO:0048168 GO:0042220 GO:0035176 GO:0016188 GO:0071625 | |
Gene3D | 2.30.42.10 3.40.50.300 | |
InterPro | IPR016313 IPR008145 IPR008144 IPR020590 IPR019590 IPR027417 IPR001478 IPR019583 IPR011511 IPR001452 | |
PANTHER | PTHR23119 | |
Pfam | PF00625 PF10608 PF00595 PF10600 PF07653 | |
PIRSF | PIRSF001741 | |
SMART | SM00072 SM00228 SM00326 | |
SUPFAM | SSF50044 SSF50156 SSF52540 | |
PROSITE | PS00856 PS50052 PS50106 PS50002 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0014069 |
postsynaptic density |
ECO:0000315 |
C |
Figure 2A- from Synaptosomal fraction found in postsynaptic density fraction of wild type and adult heterozygous reeler mice. |
complete | |||||
GO:0019717 |
synaptosome |
ECO:0000315 |
C |
Figure 2A- from Synaptosomal fraction found in postsynaptic density fraction of wild type and adult heterozygous reeler mice. Synaptosomal fraction from brain of wild type mice, figure 5A. |
complete | |||||
GO:0045202 |
synapse |
ECO:0000315 |
C |
Figure 5 shows the decrease of synaptic localization of PSD-95 in the CA1 hippocampal area of the mice with Angelman Syndrome (AS). |
complete | |||||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0005377) |
Seeded From UniProt |
complete | ||
enables |
GO:0098919 |
structural constituent of postsynaptic density |
ECO:0000305 |
curator inference used in manual assertion |
GO:0097110,GO:0098839 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0098839 |
postsynaptic density membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
enables |
GO:0097109 |
neuroligin family protein binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0008076 |
voltage-gated potassium channel complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0043197 |
dendritic spine |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002608) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035865 |
cellular response to potassium ion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(CL:0000540) |
Seeded From UniProt |
complete | ||
involved_in |
GO:2000821 |
regulation of grooming behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000463 |
positive regulation of excitatory postsynaptic potential |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000310 |
regulation of NMDA receptor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097120 |
receptor localization to synapse |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097113 |
AMPA glutamate receptor clustering |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0097110 |
scaffold protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071625 |
vocalization behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060997 |
dendritic spine morphogenesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0060076 |
excitatory synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050885 |
neuromuscular process controlling balance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050806 |
positive regulation of synaptic transmission |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0045211 |
postsynaptic membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045184 |
establishment of protein localization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0044309 |
neuron spine |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035641 |
locomotory exploration behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035418 |
protein localization to synapse |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035418 |
protein localization to synapse |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0035255 |
ionotropic glutamate receptor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035176 |
social behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0033130 |
acetylcholine receptor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0032839 |
dendrite cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0031812 |
P2Y1 nucleotide receptor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0031748 |
D1 dopamine receptor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0031697 |
beta-1 adrenergic receptor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0030165 |
PDZ domain binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0019903 |
protein phosphatase binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0008328 |
ionotropic glutamate receptor complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008022 |
protein C-terminus binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0065003 |
protein-containing complex assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002091 |
negative regulation of receptor internalization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048168 |
regulation of neuronal synaptic plasticity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042220 |
response to cocaine |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042043 |
neurexin family protein binding |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007626 |
locomotory behavior |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005198 |
structural molecule activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0006063 |
over expression analysis evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0006052 |
RNAi evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0006013 |
patch-clamp recording evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0005589 |
confocal microscopy evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0001225 |
knockout evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0099645 |
neurotransmitter receptor localization to postsynaptic specialization membrane |
ECO:0000279 |
western blot evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0006063 |
over expression analysis evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0006052 |
RNAi evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0006013 |
patch-clamp recording evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0005589 |
confocal microscopy evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0001225 |
knockout evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000279 |
western blot evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0098970 |
postsynaptic neurotransmitter receptor diffusion trapping |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002508435 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0098839 |
postsynaptic density membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1277959 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0098609 |
cell-cell adhesion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001501163 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097120 |
receptor localization to synapse |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001501163 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097113 |
AMPA glutamate receptor clustering |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001501209 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043113 |
receptor clustering |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001501163 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000563569 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0035255 |
ionotropic glutamate receptor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1277959 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0031594 |
neuromuscular junction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001624 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0030054 |
cell junction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107231 |
C |
Seeded From UniProt |
complete | ||
colocalizes_with |
GO:0008328 |
ionotropic glutamate receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1277959 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007268 |
chemical synaptic transmission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001624 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:2000463 |
positive regulation of excitatory postsynaptic potential |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:2000310 |
regulation of NMDA receptor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0150012 |
positive regulation of neuron projection arborization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0099031 |
anchored component of postsynaptic density membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0098970 |
postsynaptic neurotransmitter receptor diffusion trapping |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0098919 |
structural constituent of postsynaptic density |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0098794 |
postsynapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0097120 |
receptor localization to synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0097113 |
AMPA glutamate receptor clustering |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0097110 |
scaffold protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0097109 |
neuroligin family protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0097060 |
synaptic membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002608) |
Seeded From UniProt |
complete | ||
part_of |
GO:0071944 |
cell periphery |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0065003 |
protein-containing complex assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0061098 |
positive regulation of protein tyrosine kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0060997 |
dendritic spine morphogenesis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0060076 |
excitatory synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002608) |
Seeded From UniProt |
complete | ||
part_of |
GO:0060076 |
excitatory synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0050806 |
positive regulation of synaptic transmission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:3039785 |
P |
|
Seeded From UniProt |
complete | |
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0045211 |
postsynaptic membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002609) |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:35744) |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0045184 |
establishment of protein localization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0044309 |
neuron spine |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002608) |
Seeded From UniProt |
complete | ||
part_of |
GO:0044306 |
neuron projection terminus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0044300 |
cerebellar mossy fiber |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0044224 |
juxtaparanode region of axon |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0044224 |
juxtaparanode region of axon |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0044224 |
juxtaparanode region of axon |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035418 |
protein localization to synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035418 |
protein localization to synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035418 |
protein localization to synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0035255 |
ionotropic glutamate receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0035254 |
glutamate receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0033130 |
acetylcholine receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0032839 |
dendrite cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0032281 |
AMPA glutamate receptor complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0032281 |
AMPA glutamate receptor complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16894) |
Seeded From UniProt |
complete | ||
enables |
GO:0031812 |
P2Y1 nucleotide receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0031748 |
D1 dopamine receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0031698 |
beta-2 adrenergic receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0031697 |
beta-1 adrenergic receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0031234 |
extrinsic component of cytoplasmic side of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030863 |
cortical cytoskeleton |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030425 |
dendrite |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030425 |
dendrite |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0030165 |
PDZ domain binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0030054 |
cell junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16071)|part_of:(EMAPA:16062) |
Seeded From UniProt |
complete | ||
enables |
GO:0019903 |
protein phosphatase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019900 |
kinase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0019894 |
kinesin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019865 |
immunoglobulin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0016188 |
synaptic vesicle maturation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1915336 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0016188 |
synaptic vesicle maturation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16894) |
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16894) |
Seeded From UniProt |
complete | ||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
colocalizes_with |
GO:0008076 |
voltage-gated potassium channel complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0008022 |
protein C-terminus binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008022 |
protein C-terminus binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0008021 |
synaptic vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005911 |
cell-cell junction |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
colocalizes_with |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:17787) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005109 |
frizzled binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005102 |
signaling receptor binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0002091 |
negative regulation of receptor internalization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:68424 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0099562 |
maintenance of postsynaptic density structure |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0098919 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0099562 |
maintenance of postsynaptic density structure |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0098919 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0065003 |
protein-containing complex assembly |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045184 |
establishment of protein localization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035418 |
protein localization to synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0030863 |
cortical cytoskeleton |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019900 |
kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0008022 |
protein C-terminus binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P78352 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-MMU-443767 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030424 |
axon |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ventruti, A et al. (2011) Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain. Neuroscience 189 32-42 PubMed GONUTS page
- ↑ 2.0 2.1 Cao, C et al. (2013) Impairment of TrkB-PSD-95 signaling in Angelman syndrome. PLoS Biol. 11 e1001478 PubMed GONUTS page
- ↑ Dani, A et al. (2010) Superresolution imaging of chemical synapses in the brain. Neuron 68 843-56 PubMed GONUTS page
- ↑ Akashi, K et al. (2009) NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses. J. Neurosci. 29 10869-82 PubMed GONUTS page
- ↑ Parisiadou, L et al. (2014) LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity. Nat. Neurosci. 17 367-76 PubMed GONUTS page
- ↑ Takei, Y et al. (2015) Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A. J. Neurosci. 35 15539-54 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 Feyder, M et al. (2010) Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. Am J Psychiatry 167 1508-17 PubMed GONUTS page
- ↑ 8.0 8.1 Uchino, S et al. (2006) Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. J. Neurochem. 97 1203-14 PubMed GONUTS page
- ↑ Hung, AY et al. (2008) Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J. Neurosci. 28 1697-708 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Uemura, T et al. (2004) Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Mol. Cell. Neurosci. 26 330-41 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 Yao, WD et al. (2004) Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron 41 625-38 PubMed GONUTS page
- ↑ Irie, M et al. (1997) Binding of neuroligins to PSD-95. Science 277 1511-5 PubMed GONUTS page
- ↑ 13.00 13.01 13.02 13.03 13.04 13.05 13.06 13.07 13.08 13.09 13.10 13.11 13.12 13.13 Elias, GM et al. (2006) Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. Neuron 52 307-20 PubMed GONUTS page
- ↑ 14.00 14.01 14.02 14.03 14.04 14.05 14.06 14.07 14.08 14.09 14.10 14.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Lee, JW et al. (2016) Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function. Nat Commun 7 13123 PubMed GONUTS page
- ↑ Kerrisk, ME et al. (2013) Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J. Neurosci. 33 6742-52 PubMed GONUTS page
- ↑ Morimura, N et al. (2006) Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene 380 72-83 PubMed GONUTS page
- ↑ 18.0 18.1 Kim, S et al. (2006) NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat. Neurosci. 9 1294-301 PubMed GONUTS page
- ↑ Komiyama, NH et al. (2002) SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J. Neurosci. 22 9721-32 PubMed GONUTS page
- ↑ Pérez-Brangulí, F et al. (2014) Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia. Hum. Mol. Genet. 23 4859-74 PubMed GONUTS page
- ↑ Nakanishi, N et al. (2013) Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. J. Neurosci. 33 14170-83 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 Wentzel, C et al. (2013) mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking. Neuron 78 1012-23 PubMed GONUTS page
- ↑ Junghans, D et al. (2008) Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur. J. Neurosci. 27 559-71 PubMed GONUTS page
- ↑ Ahmad-Annuar, A et al. (2006) Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release. J. Cell Biol. 174 127-39 PubMed GONUTS page
- ↑ Gitler, D et al. (2004) Molecular determinants of synapsin targeting to presynaptic terminals. J. Neurosci. 24 3711-20 PubMed GONUTS page
- ↑ Köhr, G et al. (2003) Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction. J. Neurosci. 23 10791-9 PubMed GONUTS page
- ↑ Bamji, SX et al. (2003) Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron 40 719-31 PubMed GONUTS page
- ↑ Khalili, K et al. (2003) Puralpha is essential for postnatal brain development and developmentally coupled cellular proliferation as revealed by genetic inactivation in the mouse. Mol. Cell. Biol. 23 6857-75 PubMed GONUTS page
- ↑ Chih, B et al. (2005) Control of excitatory and inhibitory synapse formation by neuroligins. Science 307 1324-8 PubMed GONUTS page
- ↑ Osterweil, E et al. (2005) A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. J. Cell Biol. 168 329-38 PubMed GONUTS page
- ↑ Jellali, A et al. (2002) Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina. J. Comp. Neurol. 449 76-87 PubMed GONUTS page
- ↑ Horresh, I et al. (2008) Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons. J. Neurosci. 28 14213-22 PubMed GONUTS page
- ↑ 33.0 33.1 Burkhardt, C et al. (2005) Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif. FEBS Lett. 579 3821-8 PubMed GONUTS page
- ↑ Schwenk, J et al. (2012) High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron 74 621-33 PubMed GONUTS page
- ↑ Fukata, Y et al. (2005) Molecular constituents of neuronal AMPA receptors. J. Cell Biol. 169 399-404 PubMed GONUTS page
- ↑ 36.0 36.1 Schultze, W et al. (2001) Semaphorin4F interacts with the synapse-associated protein SAP90/PSD-95. J. Neurochem. 78 482-9 PubMed GONUTS page
- ↑ Jurado, S et al. (2013) LTP requires a unique postsynaptic SNARE fusion machinery. Neuron 77 542-58 PubMed GONUTS page
- ↑ Van Campenhout, CA et al. (2011) Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases. Dev. Cell 21 479-91 PubMed GONUTS page
- ↑ Yang, J et al. (2011) DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 30 165-80 PubMed GONUTS page
- ↑ 40.0 40.1 Fukata, M et al. (2004) Identification of PSD-95 palmitoylating enzymes. Neuron 44 987-96 PubMed GONUTS page
- ↑ Marschang, P et al. (2004) Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Mol. Cell. Biol. 24 3782-93 PubMed GONUTS page
- ↑ Breiderhoff, T et al. (2013) Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PLoS ONE 8 e75006 PubMed GONUTS page
- ↑ Ouyang, Q et al. (2013) Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron 80 97-112 PubMed GONUTS page
- ↑ Cook, D et al. (2011) Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus. PLoS ONE 6 e26120 PubMed GONUTS page
- ↑ Munton, RP et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol. Cell Proteomics 6 283-93 PubMed GONUTS page
- ↑ Lai, C et al. (2006) Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. J. Neurosci. 26 11798-806 PubMed GONUTS page
- ↑ Offenhäuser, N et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127 213-26 PubMed GONUTS page
- ↑ Trinidad, JC et al. (2005) Phosphorylation state of postsynaptic density proteins. J. Neurochem. 92 1306-16 PubMed GONUTS page
- ↑ Abe, M et al. (2004) NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit. J. Neurosci. 24 7292-304 PubMed GONUTS page
- ↑ Um, JW et al. (2014) Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Rep 6 1096-109 PubMed GONUTS page
- ↑ Segura, I et al. (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat. Neurosci. 10 301-10 PubMed GONUTS page
- ↑ 52.0 52.1 Aartsen, WM et al. (2006) Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse. Hum. Mol. Genet. 15 1291-302 PubMed GONUTS page
- ↑ Miyazaki, T et al. (2006) Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family. FEBS Lett. 580 4057-64 PubMed GONUTS page
a
c
- GO:0098609 ! cell-cell adhesion
- GO:0005911 ! cell-cell junction
- GO:0035865 ! cellular response to potassium ion
- GO:0030054 ! cell junction
- GO:0071944 ! cell periphery
- GO:0042995 ! cell projection
- GO:0044300 ! cerebellar mossy fiber
- GO:0007268 ! chemical synaptic transmission
- Chordata
- GO:0030863 ! cortical cytoskeleton
- Craniata
- GO:0005737 ! cytoplasm
d
e
i
m
n
- GO:0002091 ! negative regulation of receptor internalization
- GO:0042043 ! neurexin family protein binding
- GO:0097109 ! neuroligin family protein binding
- GO:0031594 ! neuromuscular junction
- GO:0050885 ! neuromuscular process controlling balance
- GO:0043005 ! neuron projection
- GO:0044306 ! neuron projection terminus
- GO:0044309 ! neuron spine
- GO:0099645 ! neurotransmitter receptor localization to postsynaptic specialization membrane
o
p
- GO:0031812 ! P2Y1 nucleotide receptor binding
- GO:0030165 ! PDZ domain binding
- GO:0005886 ! plasma membrane
- GO:0007204 ! positive regulation of cytosolic calcium ion concentration
- GO:0061098 ! positive regulation of protein tyrosine kinase activity
- GO:2000463 ! positive regulation of excitatory postsynaptic potential
- GO:0150012 ! positive regulation of neuron projection arborization
- GO:0050806 ! positive regulation of synaptic transmission
- GO:0098794 ! postsynapse
- GO:0014069 ! postsynaptic density
- GO:0098839 ! postsynaptic density membrane
- GO:0098970 ! postsynaptic neurotransmitter receptor diffusion trapping
- GO:0045211 ! postsynaptic membrane
- GO:0044877 ! protein-containing complex binding
- GO:0065003 ! protein-containing complex assembly
- GO:0019901 ! protein kinase binding
- GO:0035418 ! protein localization to synapse
- GO:0019903 ! protein phosphatase binding
r
- GO:0043113 ! receptor clustering
- GO:0097120 ! receptor localization to synapse
- GO:0048169 ! regulation of long-term neuronal synaptic plasticity
- GO:2000821 ! regulation of grooming behavior
- GO:0048168 ! regulation of neuronal synaptic plasticity
- GO:2000310 ! regulation of NMDA receptor activity
- GO:0042220 ! response to cocaine
- Rodentia
s
- GO:0097110 ! scaffold protein binding
- Sciurognathi
- GO:0005102 ! signaling receptor binding
- GO:0035176 ! social behavior
- GO:0098919 ! structural constituent of postsynaptic density
- GO:0005198 ! structural molecule activity
- GO:0045202 ! synapse
- GO:0097060 ! synaptic membrane
- GO:0016188 ! synaptic vesicle maturation
- GO:0008021 ! synaptic vesicle