GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:DLG4

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Dlg4 (synonyms: Dlgh4, Psd95)
Protein Name(s) Disks large homolog 4

Postsynaptic density protein 95 PSD-95 Synapse-associated protein 90 SAP-90 SAP90

External Links
UniProt Q62108
EMBL D50621
AL596185
AL596185
AL596185
BC014807
CCDS CCDS36202.1
CCDS48829.1
RefSeq NP_001103222.1
NP_031890.1
UniGene Mm.27256
ProteinModelPortal Q62108
SMR Q62108
BioGrid 199230
DIP DIP-29888N
IntAct Q62108
MINT MINT-136080
ChEMBL CHEMBL1795134
PhosphoSite Q62108
MaxQB Q62108
PaxDb Q62108
PRIDE Q62108
Ensembl ENSMUST00000018700
ENSMUST00000108588
ENSMUST00000108589
GeneID 13385
KEGG mmu:13385
UCSC uc007jtp.2
uc007jtq.2
CTD 1742
MGI MGI:1277959
eggNOG COG0194
GeneTree ENSGT00760000118866
HOGENOM HOG000232102
HOVERGEN HBG107814
InParanoid Q62108
KO K11828
OMA CLEDVMH
OrthoDB EOG79GT6P
PhylomeDB Q62108
TreeFam TF323171
Reactome REACT_198244
REACT_198248
REACT_198694
REACT_230679
REACT_258217
ChiTaRS Dlg4
NextBio 283740
PRO PR:Q62108
Proteomes UP000000589
Bgee Q62108
CleanEx MM_DLG4
ExpressionAtlas Q62108
Genevestigator Q62108
GO GO:0032281
GO:0030054
GO:0044300
GO:0030863
GO:0005737
GO:0030425
GO:0032839
GO:0043197
GO:0005783
GO:0060076
GO:0031234
GO:0044224
GO:0016020
GO:0044306
GO:0044309
GO:0097481
GO:0005886
GO:0014069
GO:0045211
GO:0045202
GO:0097060
GO:0008021
GO:0033130
GO:0031697
GO:0031748
GO:0035255
GO:0042043
GO:0031812
GO:0030165
GO:0008022
GO:0032403
GO:0019903
GO:0097110
GO:0005198
GO:0097113
GO:0060997
GO:0045184
GO:0007626
GO:0035641
GO:0002091
GO:0050885
GO:0007204
GO:2000463
GO:0050806
GO:0006461
GO:0035418
GO:0097120
GO:2000821
GO:0048169
GO:2000310
GO:0048168
GO:0042220
GO:0035176
GO:0016188
GO:0071625
Gene3D 2.30.42.10
3.40.50.300
InterPro IPR016313
IPR008145
IPR008144
IPR020590
IPR019590
IPR027417
IPR001478
IPR019583
IPR011511
IPR001452
PANTHER PTHR23119
Pfam PF00625
PF10608
PF00595
PF10600
PF07653
PIRSF PIRSF001741
SMART SM00072
SM00228
SM00326
SUPFAM SSF50044
SSF50156
SSF52540
PROSITE PS00856
PS50052
PS50106
PS50002

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0014069

postsynaptic density

PMID:21664258[1]

ECO:0000315

C

Figure 2A- from Synaptosomal fraction found in postsynaptic density fraction of wild type and adult heterozygous reeler mice.

complete

GO:0019717

synaptosome

PMID:21664258[1]

ECO:0000315

C

Figure 2A- from Synaptosomal fraction found in postsynaptic density fraction of wild type and adult heterozygous reeler mice. Synaptosomal fraction from brain of wild type mice, figure 5A.

complete

GO:0045202

synapse

PMID:23424281[2]

ECO:0000315

C

Figure 5 shows the decrease of synaptic localization of PSD-95 in the CA1 hippocampal area of the mice with Angelman Syndrome (AS).

complete
CACAO 7238

part_of

GO:0014069

postsynaptic density

PMID:21144999[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0005377)

Seeded From UniProt

complete

enables

GO:0098919

structural constituent of postsynaptic density

GO_REF:0000036

ECO:0000305

curator inference used in manual assertion

GO:0097110,GO:0098839

F

Seeded From UniProt

complete

part_of

GO:0098839

postsynaptic density membrane

PMID:19726645[4]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(GO:0043197)
  • part_of:(CL:0002608)
  • part_of:(UBERON:0014556)

Seeded From UniProt

complete

enables

GO:0097109

neuroligin family protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:23424281[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0008076

voltage-gated potassium channel complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

PMID:24464040[5]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002608)

Seeded From UniProt

complete

involved_in

GO:0035865

cellular response to potassium ion

PMID:26609151[6]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000540)

Seeded From UniProt

complete

involved_in

GO:2000821

regulation of grooming behavior

PMID:20952458[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000463

positive regulation of excitatory postsynaptic potential

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

involved_in

GO:2000310

regulation of NMDA receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

involved_in

GO:0097120

receptor localization to synapse

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

involved_in

GO:0097113

AMPA glutamate receptor clustering

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

enables

GO:0097110

scaffold protein binding

PMID:16606358[8]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q4ACU6

F

Seeded From UniProt

complete

involved_in

GO:0071625

vocalization behavior

PMID:20952458[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060997

dendritic spine morphogenesis

PMID:20952458[7]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0060076

excitatory synapse

PMID:18272690[9]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0050885

neuromuscular process controlling balance

PMID:20952458[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050806

positive regulation of synaptic transmission

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

colocalizes_with

GO:0045211

postsynaptic membrane

PMID:15207857[10]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045184

establishment of protein localization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P78352

P

Seeded From UniProt

complete

part_of

GO:0044309

neuron spine

PMID:16606358[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0035641

locomotory exploration behavior

PMID:20952458[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035418

protein localization to synapse

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

involved_in

GO:0035418

protein localization to synapse

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P78352

P

Seeded From UniProt

complete

enables

GO:0035255

ionotropic glutamate receptor binding

PMID:15207857[10]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q61625

F

Seeded From UniProt

complete

involved_in

GO:0035176

social behavior

PMID:20952458[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0033130

acetylcholine receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

part_of

GO:0032839

dendrite cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

enables

GO:0044877

protein-containing complex binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

enables

GO:0031812

P2Y1 nucleotide receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

enables

GO:0031748

D1 dopamine receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

enables

GO:0031697

beta-1 adrenergic receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

enables

GO:0030165

PDZ domain binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

enables

GO:0019903

protein phosphatase binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

colocalizes_with

GO:0008328

ionotropic glutamate receptor complex

PMID:15207857[10]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

F

Seeded From UniProt

complete

involved_in

GO:0007204

positive regulation of cytosolic calcium ion concentration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

involved_in

GO:0065003

protein-containing complex assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P78352

P

Seeded From UniProt

complete

involved_in

GO:0002091

negative regulation of receptor internalization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

P

Seeded From UniProt

complete

involved_in

GO:0048168

regulation of neuronal synaptic plasticity

PMID:14980210[11]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042220

response to cocaine

PMID:14980210[11]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042043

neurexin family protein binding

PMID:9278515[12]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

involved_in

GO:0007626

locomotory behavior

PMID:14980210[11]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

PMID:14980210[11]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0006063

over expression analysis evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0006052

RNAi evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0006042

cell fractionation evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0006013

patch-clamp recording evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0005589

confocal microscopy evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0001225

knockout evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099645

neurotransmitter receptor localization to postsynaptic specialization membrane

PMID:17046693[13]

ECO:0000279

western blot evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0006063

over expression analysis evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0006052

RNAi evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0006042

cell fractionation evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0006013

patch-clamp recording evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0005589

confocal microscopy evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0001225

knockout evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:17046693[13]

ECO:0000279

western blot evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0098970

postsynaptic neurotransmitter receptor diffusion trapping

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002508435
RGD:68424

P

Seeded From UniProt

complete

part_of

GO:0098839

postsynaptic density membrane

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1277959
PANTHER:PTN000563569

C

Seeded From UniProt

complete

involved_in

GO:0098609

cell-cell adhesion

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001501163
UniProtKB:Q12959
UniProtKB:Q14160

P

Seeded From UniProt

complete

involved_in

GO:0097120

receptor localization to synapse

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001501163
RGD:68424

P

Seeded From UniProt

complete

involved_in

GO:0097113

AMPA glutamate receptor clustering

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001501209
RGD:68424

P

Seeded From UniProt

complete

involved_in

GO:0043113

receptor clustering

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001501163
RGD:619895

P

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000563569
RGD:2505

C

Seeded From UniProt

complete

enables

GO:0035255

ionotropic glutamate receptor binding

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1277959
PANTHER:PTN001501163
RGD:2505
RGD:68423
RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0031594

neuromuscular junction

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001624
FB:FBgn0029830
MGI:MGI:107231
PANTHER:PTN000563569

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107231
MGI:MGI:1277959
MGI:MGI:1344351
PANTHER:PTN001501163
UniProtKB:Q12959
UniProtKB:Q14160

C

Seeded From UniProt

complete

colocalizes_with

GO:0008328

ionotropic glutamate receptor complex

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1277959
PANTHER:PTN001501163

C

Seeded From UniProt

complete

involved_in

GO:0007268

chemical synaptic transmission

PMID:21873635[14]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001624
MGI:MGI:1344351
PANTHER:PTN000563569

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:2000463

positive regulation of excitatory postsynaptic potential

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:2000310

regulation of NMDA receptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0150012

positive regulation of neuron projection arborization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

part_of

GO:0099031

anchored component of postsynaptic density membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0098970

postsynaptic neurotransmitter receptor diffusion trapping

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

enables

GO:0098919

structural constituent of postsynaptic density

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0098794

postsynapse

PMID:27759003[15]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0097120

receptor localization to synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0097113

AMPA glutamate receptor clustering

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

enables

GO:0097110

scaffold protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0097109

neuroligin family protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0097060

synaptic membrane

PMID:23595732[16]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002608)

Seeded From UniProt

complete

part_of

GO:0071944

cell periphery

PMID:16828986[17]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0065003

protein-containing complex assembly

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0061098

positive regulation of protein tyrosine kinase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060997

dendritic spine morphogenesis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

part_of

GO:0060076

excitatory synapse

PMID:16980967[18]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002608)

Seeded From UniProt

complete

part_of

GO:0060076

excitatory synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050806

positive regulation of synaptic transmission

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048169

regulation of long-term neuronal synaptic plasticity

PMID:12427827[19]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:3039785

P

  • regulates_o_occurs_in:(EMAPA:32768)
  • regulates_o_has_participant:(CL:0000117)

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

colocalizes_with

GO:0045211

postsynaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:24794856[20]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002609)

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:23986251[21]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:23791195[22]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:18279309[23]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:35744)

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:16818724[24]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:32845)
  • part_of:(CL:0000117)

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:15071120[25]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:14645471[26]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:14622577[27]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:12972605[28]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:15681343[29]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:15657400[30]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045184

establishment of protein localization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

P

Seeded From UniProt

complete

enables

GO:0044877

protein-containing complex binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0044309

neuron spine

PMID:16980967[18]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0002608)

Seeded From UniProt

complete

part_of

GO:0044306

neuron projection terminus

PMID:12115694[31]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:35744)
  • part_of:(CL:0000287)

Seeded From UniProt

complete

part_of

GO:0044300

cerebellar mossy fiber

PMID:23791195[22]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0044224

juxtaparanode region of axon

PMID:19109503[32]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:18577)
  • part_of:(CL:0000540)

Seeded From UniProt

complete

part_of

GO:0044224

juxtaparanode region of axon

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0044224

juxtaparanode region of axon

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035418

protein localization to synapse

PMID:15978582[33]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035418

protein localization to synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035418

protein localization to synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

enables

GO:0035255

ionotropic glutamate receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0035254

glutamate receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0033130

acetylcholine receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0032839

dendrite cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0032281

AMPA glutamate receptor complex

PMID:22632720[34]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032281

AMPA glutamate receptor complex

PMID:15883194[35]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:16894)

Seeded From UniProt

complete

enables

GO:0031812

P2Y1 nucleotide receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0031748

D1 dopamine receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0031698

beta-2 adrenergic receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0031697

beta-1 adrenergic receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

PMID:11483650[36]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030863

cortical cytoskeleton

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

PMID:23395379[37]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

enables

GO:0030165

PDZ domain binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

PMID:21920314[38]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:16071)|part_of:(EMAPA:16062)

Seeded From UniProt

complete

enables

GO:0019903

protein phosphatase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0019900

kinase binding

PMID:21119615[39]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

F

Seeded From UniProt

complete

enables

GO:0019894

kinesin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0019865

immunoglobulin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016188

synaptic vesicle maturation

PMID:15603741[40]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:1915336

P

  • occurs_in:(EMAPA:32845)
  • occurs_in:(CL:0000117)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016188

synaptic vesicle maturation

PMID:15603741[40]

ECO:0000314

direct assay evidence used in manual assertion

P

  • occurs_in:(EMAPA:32845)
  • occurs_in:(CL:0000117)

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:15978582[33]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:16894)

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:15082773[41]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:24069373[42]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:24035762[43]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:23791195[22]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:22022532[44]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:17114649[45]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:17093100[46]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:16894)

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:17018287[47]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:15748150[48]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:15317856[49]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:24613359[50]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:17310244[51]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P31016

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

colocalizes_with

GO:0008076

voltage-gated potassium channel complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P78352

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

part_of

GO:0008021

synaptic vesicle

PMID:16520334[52]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:17168)
  • part_of:(CL:0000604)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007204

positive regulation of cytosolic calcium ion concentration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

part_of

GO:0005911

cell-cell junction

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:16520334[52]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:17168)
  • part_of:(CL:0000604)|part_of:(EMAPA:17168)
  • part_of:(CL:0000573)

Seeded From UniProt

complete

colocalizes_with

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:16814779[53]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:17787)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:11483650[36]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005109

frizzled binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0002091

negative regulation of receptor internalization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68424

P

Seeded From UniProt

complete

involved_in

GO:0099562

maintenance of postsynaptic density structure

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0098919

P

Seeded From UniProt

complete

involved_in

GO:0099562

maintenance of postsynaptic density structure

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0098919

P

Seeded From UniProt

complete

involved_in

GO:0065003

protein-containing complex assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

P

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

C

Seeded From UniProt

complete

involved_in

GO:0045184

establishment of protein localization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

P

Seeded From UniProt

complete

involved_in

GO:0035418

protein localization to synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

P

Seeded From UniProt

complete

part_of

GO:0030863

cortical cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

C

Seeded From UniProt

complete

enables

GO:0019900

kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78352
ensembl:ENSP00000497806

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-MMU-443767

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0279

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0297

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ventruti, A et al. (2011) Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain. Neuroscience 189 32-42 PubMed GONUTS page
  2. 2.0 2.1 Cao, C et al. (2013) Impairment of TrkB-PSD-95 signaling in Angelman syndrome. PLoS Biol. 11 e1001478 PubMed GONUTS page
  3. Dani, A et al. (2010) Superresolution imaging of chemical synapses in the brain. Neuron 68 843-56 PubMed GONUTS page
  4. Akashi, K et al. (2009) NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses. J. Neurosci. 29 10869-82 PubMed GONUTS page
  5. Parisiadou, L et al. (2014) LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity. Nat. Neurosci. 17 367-76 PubMed GONUTS page
  6. Takei, Y et al. (2015) Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A. J. Neurosci. 35 15539-54 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 7.4 7.5 Feyder, M et al. (2010) Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. Am J Psychiatry 167 1508-17 PubMed GONUTS page
  8. 8.0 8.1 Uchino, S et al. (2006) Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. J. Neurochem. 97 1203-14 PubMed GONUTS page
  9. Hung, AY et al. (2008) Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J. Neurosci. 28 1697-708 PubMed GONUTS page
  10. 10.0 10.1 10.2 Uemura, T et al. (2004) Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Mol. Cell. Neurosci. 26 330-41 PubMed GONUTS page
  11. 11.0 11.1 11.2 11.3 Yao, WD et al. (2004) Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron 41 625-38 PubMed GONUTS page
  12. Irie, M et al. (1997) Binding of neuroligins to PSD-95. Science 277 1511-5 PubMed GONUTS page
  13. 13.00 13.01 13.02 13.03 13.04 13.05 13.06 13.07 13.08 13.09 13.10 13.11 13.12 13.13 Elias, GM et al. (2006) Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. Neuron 52 307-20 PubMed GONUTS page
  14. 14.00 14.01 14.02 14.03 14.04 14.05 14.06 14.07 14.08 14.09 14.10 14.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  15. Lee, JW et al. (2016) Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function. Nat Commun 7 13123 PubMed GONUTS page
  16. Kerrisk, ME et al. (2013) Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J. Neurosci. 33 6742-52 PubMed GONUTS page
  17. Morimura, N et al. (2006) Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene 380 72-83 PubMed GONUTS page
  18. 18.0 18.1 Kim, S et al. (2006) NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat. Neurosci. 9 1294-301 PubMed GONUTS page
  19. Komiyama, NH et al. (2002) SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J. Neurosci. 22 9721-32 PubMed GONUTS page
  20. Pérez-Brangulí, F et al. (2014) Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia. Hum. Mol. Genet. 23 4859-74 PubMed GONUTS page
  21. Nakanishi, N et al. (2013) Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. J. Neurosci. 33 14170-83 PubMed GONUTS page
  22. 22.0 22.1 22.2 Wentzel, C et al. (2013) mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking. Neuron 78 1012-23 PubMed GONUTS page
  23. Junghans, D et al. (2008) Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur. J. Neurosci. 27 559-71 PubMed GONUTS page
  24. Ahmad-Annuar, A et al. (2006) Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release. J. Cell Biol. 174 127-39 PubMed GONUTS page
  25. Gitler, D et al. (2004) Molecular determinants of synapsin targeting to presynaptic terminals. J. Neurosci. 24 3711-20 PubMed GONUTS page
  26. Köhr, G et al. (2003) Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction. J. Neurosci. 23 10791-9 PubMed GONUTS page
  27. Bamji, SX et al. (2003) Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron 40 719-31 PubMed GONUTS page
  28. Khalili, K et al. (2003) Puralpha is essential for postnatal brain development and developmentally coupled cellular proliferation as revealed by genetic inactivation in the mouse. Mol. Cell. Biol. 23 6857-75 PubMed GONUTS page
  29. Chih, B et al. (2005) Control of excitatory and inhibitory synapse formation by neuroligins. Science 307 1324-8 PubMed GONUTS page
  30. Osterweil, E et al. (2005) A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. J. Cell Biol. 168 329-38 PubMed GONUTS page
  31. Jellali, A et al. (2002) Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina. J. Comp. Neurol. 449 76-87 PubMed GONUTS page
  32. Horresh, I et al. (2008) Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons. J. Neurosci. 28 14213-22 PubMed GONUTS page
  33. 33.0 33.1 Burkhardt, C et al. (2005) Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif. FEBS Lett. 579 3821-8 PubMed GONUTS page
  34. Schwenk, J et al. (2012) High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron 74 621-33 PubMed GONUTS page
  35. Fukata, Y et al. (2005) Molecular constituents of neuronal AMPA receptors. J. Cell Biol. 169 399-404 PubMed GONUTS page
  36. 36.0 36.1 Schultze, W et al. (2001) Semaphorin4F interacts with the synapse-associated protein SAP90/PSD-95. J. Neurochem. 78 482-9 PubMed GONUTS page
  37. Jurado, S et al. (2013) LTP requires a unique postsynaptic SNARE fusion machinery. Neuron 77 542-58 PubMed GONUTS page
  38. Van Campenhout, CA et al. (2011) Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases. Dev. Cell 21 479-91 PubMed GONUTS page
  39. Yang, J et al. (2011) DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 30 165-80 PubMed GONUTS page
  40. 40.0 40.1 Fukata, M et al. (2004) Identification of PSD-95 palmitoylating enzymes. Neuron 44 987-96 PubMed GONUTS page
  41. Marschang, P et al. (2004) Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Mol. Cell. Biol. 24 3782-93 PubMed GONUTS page
  42. Breiderhoff, T et al. (2013) Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PLoS ONE 8 e75006 PubMed GONUTS page
  43. Ouyang, Q et al. (2013) Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron 80 97-112 PubMed GONUTS page
  44. Cook, D et al. (2011) Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus. PLoS ONE 6 e26120 PubMed GONUTS page
  45. Munton, RP et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol. Cell Proteomics 6 283-93 PubMed GONUTS page
  46. Lai, C et al. (2006) Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. J. Neurosci. 26 11798-806 PubMed GONUTS page
  47. Offenhäuser, N et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127 213-26 PubMed GONUTS page
  48. Trinidad, JC et al. (2005) Phosphorylation state of postsynaptic density proteins. J. Neurochem. 92 1306-16 PubMed GONUTS page
  49. Abe, M et al. (2004) NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit. J. Neurosci. 24 7292-304 PubMed GONUTS page
  50. Um, JW et al. (2014) Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Rep 6 1096-109 PubMed GONUTS page
  51. Segura, I et al. (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat. Neurosci. 10 301-10 PubMed GONUTS page
  52. 52.0 52.1 Aartsen, WM et al. (2006) Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse. Hum. Mol. Genet. 15 1291-302 PubMed GONUTS page
  53. Miyazaki, T et al. (2006) Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family. FEBS Lett. 580 4057-64 PubMed GONUTS page