HUMAN:WT1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	WT1
Protein Name(s)	Wilms tumor protein WT33
External Links
UniProt	P19544
EMBL	X51630 M80232 M80217 M80218 M80219 M80220 M80221 M80228 M80229 M80231 X61631 X61632 X61633 X61634 X61635 X61636 X61637 X61638 AK093168 AK291736 AY245105 AL049692 AL049692 AL049692 AL049692 CH471064 CH471064 CH471064 BC032861 M30393 S75264 S61515 S61522 S61524 S60755
CCDS	CCDS55750.1 CCDS55751.1
PIR	A38080
RefSeq	NP_000369.3 NP_001185480.1 NP_001185481.1 NP_077742.2 NP_077744.3
UniGene	Hs.591980
PDB	1LU6 1XF7 2G7T 2G7V 2G7W 2G7X 2JP9 2JPA 2PRT 3HPJ 3MYJ 4R2E 4R2P 4R2Q 4R2R 4R2S
PDBsum	1LU6 1XF7 2G7T 2G7V 2G7W 2G7X 2JP9 2JPA 2PRT 3HPJ 3MYJ 4R2E 4R2P 4R2Q 4R2R 4R2S
ProteinModelPortal	P19544
SMR	P19544
BioGrid	113327
IntAct	P19544
MINT	MINT-105556
PhosphoSite	P19544
DMDM	139778
MaxQB	P19544
PaxDb	P19544
PRIDE	P19544
DNASU	7490
Ensembl	ENST00000379079 ENST00000530998
GeneID	7490
KEGG	hsa:7490
UCSC	uc001mtl.2 uc001mtm.2 uc001mtq.2
CTD	7490
GeneCards	GC11M032365
GeneReviews	WT1
H-InvDB	HIX0009531
HGNC	HGNC:12796
HPA	CAB000327 HPA053848
MIM	136680 156240 194070 194080 256370 607102 608978
neXtProt	NX_P19544
Orphanet	251510 220 83469 93217 93213 347 3097 654 93220 893
PharmGKB	PA37395
eggNOG	COG5048
GeneTree	ENSGT00550000074455
HOVERGEN	HBG006960
InParanoid	P19544
KO	K09234
OrthoDB	EOG7NPFT8
PhylomeDB	P19544
SignaLink	P19544
ChiTaRS	WT1
EvolutionaryTrace	P19544
GeneWiki	WT1
GenomeRNAi	7490
NextBio	29336
PRO	PR:P19544
Proteomes	UP000005640
Bgee	P19544
CleanEx	HS_WT1
ExpressionAtlas	P19544
Genevestigator	P19544
GO	GO:0005737 GO:0016607 GO:0005654 GO:0005634 GO:0070742 GO:0003723 GO:0001077 GO:0043565 GO:0003700 GO:0044212 GO:0008270 GO:0035802 GO:0030325 GO:0001658 GO:0043010 GO:0060923 GO:0071320 GO:0071371 GO:0060539 GO:0030855 GO:0007281 GO:0032836 GO:0072112 GO:0032835 GO:0008406 GO:0007507 GO:0001822 GO:0030539 GO:0008584 GO:0060231 GO:0072207 GO:0072075 GO:0072284 GO:0043066 GO:0030308 GO:0008285 GO:2000195 GO:0072302 GO:0000122 GO:0045892 GO:0017148 GO:0043065 GO:0060421 GO:2000020 GO:2001076 GO:0045944 GO:0045893 GO:0072166 GO:0003156 GO:0006357 GO:0006355 GO:0008380 GO:0007530 GO:0007356 GO:0009888 GO:0001657 GO:0001570 GO:0061032
Gene3D	3.30.160.60
InterPro	IPR017987 IPR000976 IPR007087 IPR015880 IPR013087
Pfam	PF02165 PF00096
PRINTS	PR00049
SMART	SM00355
PROSITE	PS00028 PS50157

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[1]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[1]	ECO:0000255	match to sequence model evidence used in manual assertion	InterPro:IPR000976	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000113	ECO:0005556	multiple sequence alignment evidence used in manual assertion	UniProtKB:E9Q3T6 UniProtKB:O14978 UniProtKB:O95125 UniProtKB:O95863 UniProtKB:P10071 UniProtKB:P10754 UniProtKB:P17028 UniProtKB:P28698 UniProtKB:P36508 UniProtKB:P41183 UniProtKB:P47806 UniProtKB:P52738 UniProtKB:Q02085 UniProtKB:Q05516 UniProtKB:Q08376 UniProtKB:Q0VDQ9 UniProtKB:Q16600 UniProtKB:Q61967 UniProtKB:Q6DJT9 UniProtKB:Q6NUN9 UniProtKB:Q86UQ0 UniProtKB:Q8CIV7 UniProtKB:Q8K0L9 UniProtKB:Q8K3J5 UniProtKB:Q8NI51 UniProtKB:Q91ZD1 UniProtKB:Q96RE9 UniProtKB:Q99684 UniProtKB:Q9BU19 UniProtKB:Q9ESP5 UniProtKB:Q9GZX5 UniProtKB:Q9H116 UniProtKB:Q9NQX1 UniProtKB:Q9NZL3 UniProtKB:Q9QY31 UniProtKB:Q9UM63 UniProtKB:Q9UPG8 UniProtKB:Q9UQR1 UniProtKB:Q9WTJ2 UniProtKB:Q9Y2X9 UniProtKB:Q9Y473 UniProtKB:Q9Y5A6	F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:23042785^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(ENSEMBL:ENSG00000119772) occurs_at:(SO:0001952) part_of:(GO:0045944)	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:23042785^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	regulates_expression_of:(ENSEMBL:ENSG00000119772)\|regulates_expression_of:(ENSEMBL:ENSG00000142182)	Seeded From UniProt	complete
acts_upstream_of	GO:1905643	positive regulation of DNA methylation	PMID:23042785^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_at:(SO:0001952) has_input:(ENSEMBL:ENSG00000076242) part_of:(GO:0000122)\|occurs_at(SO:0001952) has_input:(ENSEMBL:ENSG00000112246) part_of:(GO:0000122)\|occurs_at(SO:0001952) has_input:(ENSEMBL:ENSG00000092969) part_of:(GO:0000122)\|occurs_at(SO:0001952) has_input:(ENSEMBL:ENSG00000091831)	Seeded From UniProt	complete
acts_upstream_of	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:23042785^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	regulates_transcription_of:(ENSEMBL:ENSG00000076242)\|regulates_transcription_of:(ENSEMBL:ENSG00000112246)\|regulates_transcription_of:(ENSEMBL:ENSG00000092969)	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:23042785^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(ENSEMBL:ENSG00000119772) occurs_at:(SO:0001952)	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:23042785^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_transcription_of:(ENSEMBL:ENSG00000119772)	Seeded From UniProt	complete
involved_in	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	PMID:23042785^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0044729	hemi-methylated DNA-binding	PMID:25258363^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0010385	double-stranded methylated DNA binding	PMID:25258363^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:25258363^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	PMID:25258363^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0060923	cardiac muscle cell fate commitment	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:2001076	positive regulation of metanephric ureteric bud development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:2000195	negative regulation of female gonad development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:2000020	positive regulation of male gonad development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0072284	metanephric S-shaped body morphogenesis	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0072207	metanephric epithelium development	PMID:7856737^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0072166	posterior mesonephric tubule development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0072112	glomerular visceral epithelial cell differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0072075	metanephric mesenchyme development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0071371	cellular response to gonadotropin stimulus	PMID:15961562^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071320	cellular response to cAMP	PMID:15961562^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0070742	C2H2 zinc finger domain binding	PMID:8119964^[7]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P19544	F		Seeded From UniProt	complete
involved_in	GO:0061032	visceral serous pericardium development	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0060539	diaphragm development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0060421	positive regulation of heart growth	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0060231	mesenchymal to epithelial transition	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:11912180^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:21390327^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:8132626^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:14701728^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:12802290^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9765217^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9178767^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9553041^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:16467207^[16]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:14701728^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:7585606^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:12802290^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:1332065^[18]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:7720589^[19]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:19050011^[20]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:8119964^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:7585606^[17]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:1332065^[18]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:16467207^[16]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:1662794^[23]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:7720589^[19]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:8119964^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0043010	camera-type eye development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0035802	adrenal cortex formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0032836	glomerular basement membrane development	PMID:19205749^[24]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032835	glomerulus development	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0030855	epithelial cell differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0030539	male genitalia development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0030325	adrenal gland development	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0030308	negative regulation of cell growth	PMID:9553041^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030308	negative regulation of cell growth	PMID:9765217^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	PMID:16934801^[25]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	PMID:9553041^[15]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000653)	Seeded From UniProt	complete
involved_in	GO:0009888	tissue development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0008584	male gonad development	PMID:17848411^[26]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008406	gonad development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0008380	RNA splicing	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	PMID:9765217^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	PMID:9553041^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	PMID:15518539^[27]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007530	sex determination	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0007356	thorax and anterior abdomen determination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0007281	germ cell development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	PMID:7862533^[28]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	PMID:8393820^[29]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16934801^[25]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:15961562^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:14701728^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:8306891^[30]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:1662794^[23]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:7862533^[28]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:8393820^[29]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	F	has_direct_input:(UniProtKB:P08046)	Seeded From UniProt	complete
involved_in	GO:0003156	regulation of animal organ formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	PMID:11912180^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0001658	branching involved in ureteric bud morphogenesis	PMID:10101119^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0001657	ureteric bud development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
involved_in	GO:0001570	vasculogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P22561	F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
involved_in	GO:0072112	glomerular visceral epithelial cell differentiation	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98968 PANTHER:PTN002397252	P		Seeded From UniProt	complete
involved_in	GO:0071371	cellular response to gonadotropin stimulus	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002397252 UniProtKB:P19544	P		Seeded From UniProt	complete
involved_in	GO:0071320	cellular response to cAMP	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002397252 UniProtKB:P19544	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98968 PANTHER:PTN002397252 UniProtKB:P19544	P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002397252 UniProtKB:P19544	P		Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1338056 MGI:MGI:1342287 MGI:MGI:1354948 MGI:MGI:2153049 MGI:MGI:2153568 MGI:MGI:2181068 MGI:MGI:98968 PANTHER:PTN001145452 RGD:3738 UniProtKB:A0A1D8PNL1 UniProtKB:Q02446 UniProtKB:Q7RTV3 ZFIN:ZDB-GENE-021115-9	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0043364 FB:FBgn0261434 FB:FBgn0263239 MGI:MGI:1101353 MGI:MGI:1277166 MGI:MGI:1333856 MGI:MGI:1338056 MGI:MGI:1342287 MGI:MGI:1342772 MGI:MGI:1346318 MGI:MGI:1929988 MGI:MGI:1932575 MGI:MGI:2153568 MGI:MGI:95295 MGI:MGI:95296 MGI:MGI:98372 MGI:MGI:98968 PANTHER:PTN001145452 RGD:1306768 RGD:2544 RGD:3738 RGD:3741 RGD:3974 RGD:621445 RGD:621652 RGD:62389 UniProtKB:A0A0B4KHC8 UniProtKB:A0A0G2K5M1 UniProtKB:P18146 UniProtKB:P19544 UniProtKB:Q02086 UniProtKB:Q13351 UniProtKB:Q13886 UniProtKB:Q7RTV3 UniProtKB:Q8TDD2 UniProtKB:Q99612 UniProtKB:Q9UIH9 WB:WBGene00007772 WB:WBGene00012735	C		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:21873635^[31]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001145452 UniProtKB:O14901 UniProtKB:Q9Y5W3 WB:WBGene00012735 ZFIN:ZDB-GENE-021115-9	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:7585606^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013087	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000976	C		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000976	P		Seeded From UniProt	complete
NOT\|involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	PMID:15520190^[32]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030308	negative regulation of cell growth	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0017148	negative regulation of translation	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043065	positive regulation of apoptotic process	PMID:7588596^[21]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:9815658^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	PMID:15520190^[32]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0186	C		Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0188	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0190	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Szemes, M et al. (2013) Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A. Hum. Mol. Genet. 22 74-83 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Hashimoto, H et al. (2014) Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev. 28 2304-13 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 Moore, AW et al. (1999) YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development 126 1845-57 PubMed GONUTS page
↑ Eccles, MR et al. (1995) Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors. Am. J. Pathol. 146 40-5 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Ferretti, E et al. (2005) Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines. Endocrinology 146 4009-15 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Rupprecht, HD et al. (1994) The Wilms' tumor suppressor gene WT1 is negatively autoregulated. J. Biol. Chem. 269 6198-206 PubMed GONUTS page
↑ ^8.0 ^8.1 Guo, JK et al. (2002) WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis. Hum. Mol. Genet. 11 651-9 PubMed GONUTS page
↑ Wang, D et al. (2011) PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression. PLoS ONE 6 e17048 PubMed GONUTS page
↑ Fraizer, GC et al. (1994) Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. J. Biol. Chem. 269 8892-900 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 Carpenter, B et al. (2004) BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1. Mol. Cell. Biol. 24 537-49 PubMed GONUTS page
↑ ^12.0 ^12.1 Udtha, M et al. (2003) Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors. Oncogene 22 3821-6 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 Guan, LS et al. (1998) Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition. J. Biol. Chem. 273 27047-50 PubMed GONUTS page
↑ McConnell, MJ et al. (1997) Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2. Oncogene 14 2689-700 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 ^15.3 Maheswaran, S et al. (1998) Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70. Genes Dev. 12 1108-20 PubMed GONUTS page
↑ ^16.0 ^16.1 Dame, C et al. (2006) Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene. Blood 107 4282-90 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 Hewitt, SM et al. (1995) Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1. Cancer Res. 55 5386-9 PubMed GONUTS page
↑ ^18.0 ^18.1 Gashler, AL et al. (1992) Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc. Natl. Acad. Sci. U.S.A. 89 10984-8 PubMed GONUTS page
↑ ^19.0 ^19.1 Ryan, G et al. (1995) Repression of Pax-2 by WT1 during normal kidney development. Development 121 867-75 PubMed GONUTS page
↑ Green, LM et al. (2009) Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation. Nucleic Acids Res. 37 431-40 PubMed GONUTS page
↑ ^21.0 ^21.1 ^21.2 ^21.3 ^21.4 ^21.5 ^21.6 Englert, C et al. (1995) WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis. EMBO J. 14 4662-75 PubMed GONUTS page
↑ ^22.0 ^22.1 ^22.2 ^22.3 ^22.4 ^22.5 ^22.6 ^22.7 ^22.8 ^22.9 Shimamura, R et al. (1997) The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor. Clin. Cancer Res. 3 2571-80 PubMed GONUTS page
↑ ^23.0 ^23.1 Morris, JF et al. (1991) Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus. Oncogene 6 2339-48 PubMed GONUTS page
↑ Bockenhauer, D et al. (2009) Membranoproliferative glomerulonephritis associated with a mutation in Wilms' tumour suppressor gene 1. Pediatr. Nephrol. 24 1399-401 PubMed GONUTS page
↑ ^25.0 ^25.1 Markus, MA et al. (2006) WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Exp. Cell Res. 312 3379-88 PubMed GONUTS page
↑ O'Shaughnessy, PJ et al. (2007) Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester. J. Clin. Endocrinol. Metab. 92 4792-801 PubMed GONUTS page
↑ Lachenmann, MJ et al. (2004) Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity. Biochemistry 43 13910-25 PubMed GONUTS page
↑ ^28.0 ^28.1 Hamilton, TB et al. (1995) High affinity binding sites for the Wilms' tumour suppressor protein WT1. Nucleic Acids Res. 23 277-84 PubMed GONUTS page
↑ ^29.0 ^29.1 Rauscher, FJ 3rd (1993) The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. FASEB J. 7 896-903 PubMed GONUTS page
↑ Mundlos, S et al. (1993) Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues. Development 119 1329-41 PubMed GONUTS page
↑ ^31.0 ^31.1 ^31.2 ^31.3 ^31.4 ^31.5 ^31.6 ^31.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^32.0 ^32.1 Smolen, GA et al. (2004) SUMO-1 modification of the Wilms' tumor suppressor WT1. Cancer Res. 64 7846-51 PubMed GONUTS page

[PMID:19274049-1] 1.0 ^1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page

[PMID:23042785-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Szemes, M et al. (2013) Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A. Hum. Mol. Genet. 22 74-83 PubMed GONUTS page

[PMID:25258363-3] 3.0 ^3.1 ^3.2 ^3.3 Hashimoto, H et al. (2014) Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev. 28 2304-13 PubMed GONUTS page

[PMID:10101119-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 Moore, AW et al. (1999) YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development 126 1845-57 PubMed GONUTS page

[PMID:7856737-5] Eccles, MR et al. (1995) Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors. Am. J. Pathol. 146 40-5 PubMed GONUTS page

[PMID:15961562-6] 6.0 ^6.1 ^6.2 Ferretti, E et al. (2005) Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines. Endocrinology 146 4009-15 PubMed GONUTS page

[PMID:8119964-7] 7.0 ^7.1 ^7.2 Rupprecht, HD et al. (1994) The Wilms' tumor suppressor gene WT1 is negatively autoregulated. J. Biol. Chem. 269 6198-206 PubMed GONUTS page

[PMID:11912180-8] 8.0 ^8.1 Guo, JK et al. (2002) WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis. Hum. Mol. Genet. 11 651-9 PubMed GONUTS page

[PMID:21390327-9] Wang, D et al. (2011) PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression. PLoS ONE 6 e17048 PubMed GONUTS page

[PMID:8132626-10] Fraizer, GC et al. (1994) Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. J. Biol. Chem. 269 8892-900 PubMed GONUTS page

[PMID:14701728-11] 11.0 ^11.1 ^11.2 Carpenter, B et al. (2004) BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1. Mol. Cell. Biol. 24 537-49 PubMed GONUTS page

[PMID:12802290-12] 12.0 ^12.1 Udtha, M et al. (2003) Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors. Oncogene 22 3821-6 PubMed GONUTS page

[PMID:9765217-13] 13.0 ^13.1 ^13.2 Guan, LS et al. (1998) Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition. J. Biol. Chem. 273 27047-50 PubMed GONUTS page

[PMID:9178767-14] McConnell, MJ et al. (1997) Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2. Oncogene 14 2689-700 PubMed GONUTS page

[PMID:9553041-15] 15.0 ^15.1 ^15.2 ^15.3 Maheswaran, S et al. (1998) Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70. Genes Dev. 12 1108-20 PubMed GONUTS page

[PMID:16467207-16] 16.0 ^16.1 Dame, C et al. (2006) Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene. Blood 107 4282-90 PubMed GONUTS page

[PMID:7585606-17] 17.0 ^17.1 ^17.2 Hewitt, SM et al. (1995) Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1. Cancer Res. 55 5386-9 PubMed GONUTS page

[PMID:1332065-18] 18.0 ^18.1 Gashler, AL et al. (1992) Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc. Natl. Acad. Sci. U.S.A. 89 10984-8 PubMed GONUTS page

[PMID:7720589-19] 19.0 ^19.1 Ryan, G et al. (1995) Repression of Pax-2 by WT1 during normal kidney development. Development 121 867-75 PubMed GONUTS page

[PMID:19050011-20] Green, LM et al. (2009) Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation. Nucleic Acids Res. 37 431-40 PubMed GONUTS page

[PMID:7588596-21] 21.0 ^21.1 ^21.2 ^21.3 ^21.4 ^21.5 ^21.6 Englert, C et al. (1995) WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis. EMBO J. 14 4662-75 PubMed GONUTS page

[PMID:9815658-22] 22.0 ^22.1 ^22.2 ^22.3 ^22.4 ^22.5 ^22.6 ^22.7 ^22.8 ^22.9 Shimamura, R et al. (1997) The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor. Clin. Cancer Res. 3 2571-80 PubMed GONUTS page

[PMID:1662794-23] 23.0 ^23.1 Morris, JF et al. (1991) Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus. Oncogene 6 2339-48 PubMed GONUTS page

[PMID:19205749-24] Bockenhauer, D et al. (2009) Membranoproliferative glomerulonephritis associated with a mutation in Wilms' tumour suppressor gene 1. Pediatr. Nephrol. 24 1399-401 PubMed GONUTS page

[PMID:16934801-25] 25.0 ^25.1 Markus, MA et al. (2006) WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Exp. Cell Res. 312 3379-88 PubMed GONUTS page

[PMID:17848411-26] O'Shaughnessy, PJ et al. (2007) Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester. J. Clin. Endocrinol. Metab. 92 4792-801 PubMed GONUTS page

[PMID:15518539-27] Lachenmann, MJ et al. (2004) Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity. Biochemistry 43 13910-25 PubMed GONUTS page

[PMID:7862533-28] 28.0 ^28.1 Hamilton, TB et al. (1995) High affinity binding sites for the Wilms' tumour suppressor protein WT1. Nucleic Acids Res. 23 277-84 PubMed GONUTS page

[PMID:8393820-29] 29.0 ^29.1 Rauscher, FJ 3rd (1993) The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. FASEB J. 7 896-903 PubMed GONUTS page

[PMID:8306891-30] Mundlos, S et al. (1993) Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues. Development 119 1329-41 PubMed GONUTS page

[PMID:21873635-31] 31.0 ^31.1 ^31.2 ^31.3 ^31.4 ^31.5 ^31.6 ^31.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15520190-32] 32.0 ^32.1 Smolen, GA et al. (2004) SUMO-1 modification of the Wilms' tumor suppressor WT1. Cancer Res. 64 7846-51 PubMed GONUTS page

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HUMAN:WT1

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