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Category:apolipoproteins involved in RCT

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Annotation of reverse cholesterol transport associated human apolipoproteins started in May 2009 as part of the cardiovascular GO annotation initiative, at UCL. For more information please contact r.lovering@ucl.ac.uk

Aspect ID Term HUMAN

APOA1

HUMAN

APOE

HUMAN

APOA2

HUMAN

APOM

HUMAN

APOA4

HUMAN

APOC3

HUMAN

APOC2

HUMAN

APOA5

Biological ProcessGO:0000302response to reactive oxygen species NAS
Biological ProcessGO:0001523retinoid metabolic process TAS TAS TAS TAS TAS TAS TAS
Biological ProcessGO:0001937negative regulation of endothelial cell proliferation IDA
Biological ProcessGO:0002227innate immune response in mucosa IDA
Biological ProcessGO:0002576platelet degranulation TAS
Biological ProcessGO:0002740negative regulation of cytokine secretion involved in immune response IDA IDA
Biological ProcessGO:0006457protein folding IDA
Biological ProcessGO:0006629lipid metabolic process TAS TAS TAS TAS TAS TAS
Biological ProcessGO:0006641triglyceride metabolic process IDA  IMP TAS IMP IDA  IMP
Biological ProcessGO:0006656phosphatidylcholine biosynthetic process IDA IDA
Biological ProcessGO:0006695cholesterol biosynthetic process IBA IBA IBA IBA
Biological ProcessGO:0006707cholesterol catabolic process IBA
Biological ProcessGO:0006869lipid transport IDA  TAS IDA
Biological ProcessGO:0006898receptor-mediated endocytosis TAS IDA  TAS
Biological ProcessGO:0006916anti-apoptosis IDA
Biological ProcessGO:0006917induction of apoptosis IDA
Biological ProcessGO:0006982response to lipid hydroperoxide IDA
Biological ProcessGO:0007010cytoskeleton organization TAS
Biological ProcessGO:0007159leukocyte cell-cell adhesion IDA
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayNOT IDA
Biological ProcessGO:0007186G-protein coupled receptor protein signaling pathway IDA IDA IDA
Biological ProcessGO:0007229integrin-mediated signaling pathway IDA
Biological ProcessGO:0007263nitric oxide mediated signal transduction IDA
Biological ProcessGO:0007271synaptic transmission, cholinergic TAS
Biological ProcessGO:0007596blood coagulation TAS
Biological ProcessGO:0007603phototransduction, visible light TAS TAS TAS TAS TAS TAS TAS
Biological ProcessGO:0008203cholesterol metabolic process IDA  IMP IDA  IMP IDA
Biological ProcessGO:0009395phospholipid catabolic process IDA IDA
Biological ProcessGO:0009749response to glucose stimulus IDA
Biological ProcessGO:0010518positive regulation of phospholipase activity IDA
Biological ProcessGO:0010544negative regulation of platelet activation IDA
Biological ProcessGO:0010804negative regulation of tumor necrosis factor-mediated signaling pathway IDA
Biological ProcessGO:0010873positive regulation of cholesterol esterifi... IDA IDA  IMP IDA IDA IBA
Biological ProcessGO:0010875positive regulation of cholesterol efflux IDA  IGI
Biological ProcessGO:0010897negative regulation of triglyceride catabol... IDA
Biological ProcessGO:0010898positive regulation of triglyceride catabolic process IBA IDA IDA IDA
Biological ProcessGO:0010902positive regulation of very-low-density lipoprotein particle remodeling IC IDA
Biological ProcessGO:0010903negative regulation of very-low-density lipoprotein particle remodeling IDA IDA IC  IDA
Biological ProcessGO:0010916negative regulation of very-low-density lipoprotein particle clearance IDA IDA
Biological ProcessGO:0010987negative regulation of high-density lipoprotein particle clearance IMP
Biological ProcessGO:0010989negative regulation of low-density lipoprotein particle clearance IMP
Biological ProcessGO:0015909long-chain fatty acid transport IDA
Biological ProcessGO:0017038protein import IDA
Biological ProcessGO:0018158protein oxidation IDA IDA
Biological ProcessGO:0018206peptidyl-methionine modification IDA IDA
Biological ProcessGO:0019068virion assembly IMP
Biological ProcessGO:0019430removal of superoxide radicals IDA
Biological ProcessGO:0019433triglyceride catabolic process IBA IBA IBA IDA IMP
Biological ProcessGO:0019934cGMP-mediated signaling IDA
Biological ProcessGO:0030168platelet activation TAS
Biological ProcessGO:0030195negative regulation of blood coagulation IDA
Biological ProcessGO:0030300regulation of intestinal cholesterol absorption IBA IBA IBA
Biological ProcessGO:0030301cholesterol transport IDA
Biological ProcessGO:0030516regulation of axon extension TAS
Biological ProcessGO:0030828positive regulation of cGMP biosynthetic process IDA
Biological ProcessGO:0031102neuron projection regeneration IBA IBA IBA IBA
Biological ProcessGO:0031647regulation of protein stability IDA
Biological ProcessGO:0032374regulation of cholesterol transport IDA
Biological ProcessGO:0032375negative regulation of cholesterol transport IDA  IMP IMP IMP
Biological ProcessGO:0032410negative regulation of transporter activity IDA
Biological ProcessGO:0032488Cdc42 protein signal transduction IDA IDA IDA
Biological ProcessGO:0032489regulation of Cdc42 protein signal transduction IDA IDA IDA
Biological ProcessGO:0032805positive regulation of low-density lipoprot... IDA
Biological ProcessGO:0033344cholesterol efflux IDA  IMP IDA IDA IDA  IMP IDA IDA IDA IBA
Biological ProcessGO:0033700phospholipid efflux IDA IDA IDA IDA IDA IDA IBA
Biological ProcessGO:0034014response to triglyceride IDA
Biological ProcessGO:0034115negative regulation of heterotypic cell-cell adhesion IDA
Biological ProcessGO:0034370triglyceride-rich lipoprotein particle remo... IDA TAS
Biological ProcessGO:0034371chylomicron remodeling IC IC
Biological ProcessGO:0034372very-low-density lipoprotein particle remodeling IBA IDA  IGI IDA TAS IBA
Biological ProcessGO:0034374low-density lipoprotein particle remodeling IDA
Biological ProcessGO:0034375high-density lipoprotein particle remodeling IC  IDA IGI IDA IMP IC IMP
Biological ProcessGO:0034378chylomicron assembly TAS
Biological ProcessGO:0034379very-low-density lipoprotein particle assembly IDA  TAS
Biological ProcessGO:0034380high-density lipoprotein particle assembly IDA IDA IDA ISS IBA IBA
Biological ProcessGO:0034381lipoprotein particle clearance TAS
Biological ProcessGO:0034382chylomicron remnant clearance IMP IDA IDA
Biological ProcessGO:0034383low-density lipoprotein particle clearance IMP
Biological ProcessGO:0034384high-density lipoprotein particle clearance IC  IDA IDA IDA ISS IMP IMP IDA
Biological ProcessGO:0034445negative regulation of plasma lipoprotein particle oxidation IDA IDA
Biological ProcessGO:0034447very-low-density lipoprotein particle clear... IDA  IMP IDA
Biological ProcessGO:0035025positive regulation of Rho protein signal transduction IDA
Biological ProcessGO:0042157lipoprotein metabolic process IBA  TAS TAS TAS IBA  TAS TAS TAS IBA
Biological ProcessGO:0042159lipoprotein catabolic process IBA
Biological ProcessGO:0042246tissue regeneration IEP
Biological ProcessGO:0042632cholesterol homeostasis IDA  IMP IDA IDA IC IDA IMP IC IDA
Biological ProcessGO:0042744hydrogen peroxide catabolic process IDA
Biological ProcessGO:0043085positive regulation of catalytic activity IDA
Biological ProcessGO:0043086negative regulation of catalytic activity IDA
Biological ProcessGO:0043407negative regulation of MAP kinase activity IDA
Biological ProcessGO:0043524negative regulation of neuron apoptotic process IBA
Biological ProcessGO:0043537negative regulation of blood vessel endothelial cell migration IDA
Biological ProcessGO:0043691reverse cholesterol transport IMP IDA IDA ISS IDA IC IC IBA
Biological ProcessGO:0044240multicellular organismal lipid catabolic pr... IDA
Biological ProcessGO:0044255cellular lipid metabolic process TAS TAS TAS
Biological ProcessGO:0044281small molecule metabolic process TAS TAS TAS TAS TAS TAS TAS
Biological ProcessGO:0044794positive regulation by host of viral process IMP
Biological ProcessGO:0045416positive regulation of interleukin-8 biosynthetic process IDA
Biological ProcessGO:0045541negative regulation of cholesterol biosynthetic process IDA
Biological ProcessGO:0045717negative regulation of fatty acid biosynthe... IDA
Biological ProcessGO:0045723positive regulation of fatty acid biosynthetic process IBA IDA IDA IDA
Biological ProcessGO:0045833negative regulation of lipid metabolic process IDA IDA
Biological ProcessGO:0046340diacylglycerol catabolic process IDA
Biological ProcessGO:0046470phosphatidylcholine metabolic process IDA IBA
Biological ProcessGO:0046889positive regulation of lipid biosynthetic process IDA
Biological ProcessGO:0046907intracellular transport TAS
Biological ProcessGO:0048168regulation of neuronal synaptic plasticity TAS
Biological ProcessGO:0048260positive regulation of receptor-mediated en... TAS
Biological ProcessGO:0048261negative regulation of receptor-mediated en... IDA IDA
Biological ProcessGO:0050713negative regulation of interleukin-1 beta secretion IDA
Biological ProcessGO:0050728negative regulation of inflammatory response IDA IC
Biological ProcessGO:0050821protein stabilization IDA
Biological ProcessGO:0050919negative chemotaxis IDA
Biological ProcessGO:0050995negative regulation of lipid catabolic process IDA IDA
Biological ProcessGO:0050996positive regulation of lipid catabolic process IDA IDA
Biological ProcessGO:0051000positive regulation of nitric-oxide synthase activity IDA
Biological ProcessGO:0051005negative regulation of lipoprotein lipase a... IDA
Biological ProcessGO:0051006positive regulation of lipoprotein lipase activity IBA IDA IDA IDA
Biological ProcessGO:0051044positive regulation of membrane protein ectodomain proteolysis IDA
Biological ProcessGO:0051055negative regulation of lipid biosynthetic process IDA
Biological ProcessGO:0051180vitamin transport IMP
Biological ProcessGO:0051345positive regulation of hydrolase activity IDA
Biological ProcessGO:0051496positive regulation of stress fiber assembly IDA
Biological ProcessGO:0055085transmembrane transport TAS
Biological ProcessGO:0055088lipid homeostasis IDA
Biological ProcessGO:0055089fatty acid homeostasis IDA
Biological ProcessGO:0055090acylglycerol homeostasis IDA  IMP
Biological ProcessGO:0055091phospholipid homeostasis IDA
Biological ProcessGO:0060192negative regulation of lipase activity IDA
Biological ProcessGO:0060354negative regulation of cell adhesion molecule production IDA
Biological ProcessGO:0060621negative regulation of cholesterol import IDA IMP
Biological ProcessGO:0060695negative regulation of cholesterol transporter activity IDA
Biological ProcessGO:0060697positive regulation of phospholipid catabolic process IDA
Biological ProcessGO:0060761negative regulation of response to cytokine stimulus IDA
Biological ProcessGO:0060999positive regulation of dendritic spine development IDA
Biological ProcessGO:0061000negative regulation of dendritic spine development IDA
Biological ProcessGO:0065005protein-lipid complex assembly IMP
Biological ProcessGO:0070328triglyceride homeostasis IDA IBA IMP IMP IDA  IMP
Biological ProcessGO:0070371ERK1 and ERK2 cascadeNOT IDA
Biological ProcessGO:0070508cholesterol import IMP
Biological ProcessGO:0071830triglyceride-rich lipoprotein particle clearance IDA
Biological ProcessGO:0090370negative regulation of cholesterol efflux IDA
Biological ProcessGO:0097113AMPA glutamate receptor clustering IDA
Biological ProcessGO:0097114NMDA glutamate receptor clustering IDA
Biological ProcessGO:1900026positive regulation of substrate adhesion-dependent cell spreading IDA
Biological ProcessGO:1900221regulation of beta-amyloid clearance IDA
Biological ProcessGO:1901214regulation of neuron death IDA
Biological ProcessGO:1901215negative regulation of neuron death IDA
Biological ProcessGO:1901216positive regulation of neuron death IDA
Biological ProcessGO:1901627negative regulation of postsynaptic membrane organization IDA
Biological ProcessGO:1901628positive regulation of postsynaptic membrane organization IDA
Biological ProcessGO:1901630negative regulation of presynaptic membrane organization IDA
Biological ProcessGO:1901631positive regulation of presynaptic membrane organization IDA
Biological ProcessGO:1902004positive regulation of beta-amyloid formation IDA
Biological ProcessGO:1902430negative regulation of beta-amyloid formation IDA
Biological ProcessGO:1902947regulation of tau-protein kinase activity IDA
Biological ProcessGO:1902951negative regulation of dendritic spine maintenance IDA
Biological ProcessGO:1902952positive regulation of dendritic spine maintenance IDA
Biological ProcessGO:1902995positive regulation of phospholipid efflux IDA
Biological ProcessGO:1902998positive regulation of neurofibrillary tangle assembly IDA
Biological ProcessGO:1902999negative regulation of phospholipid efflux IDA
Biological ProcessGO:1903001negative regulation of lipid transport across blood brain barrier IDA
Biological ProcessGO:1903002positive regulation of lipid transport across blood brain barrier IDA
Cellular ComponentGO:0005576extracellular region TAS TAS NAS  TAS TAS NAS  TAS TAS NAS  TAS IDA  TAS
Cellular ComponentGO:0005615extracellular space IDA  ISS IDA IDA IDA IDA IDA
Cellular ComponentGO:0005634nucleus IDA IDA
Cellular ComponentGO:0005737cytoplasm NAS  TAS IDA
Cellular ComponentGO:0005769early endosome TAS TAS TAS TAS TAS TAS
Cellular ComponentGO:0005783endoplasmic reticulum IDA
Cellular ComponentGO:0005788endoplasmic reticulum lumen EXP  TAS EXP  TAS EXP  TAS
Cellular ComponentGO:0005794Golgi apparatus IDA
Cellular ComponentGO:0005829cytosol TAS TAS TAS
Cellular ComponentGO:0005886plasma membrane TAS TAS
Cellular ComponentGO:0005887integral to plasma membrane TAS
Cellular ComponentGO:0009986cell surfacecolocalizes_with IDA
Cellular ComponentGO:0016020membrane IDA
Cellular ComponentGO:0030141stored secretory granule TAS
Cellular ComponentGO:0030425dendrite NAS
Cellular ComponentGO:0031012extracellular matrix IDA
Cellular ComponentGO:0031410cytoplasmic vesicle IDA
Cellular ComponentGO:0034361very-low-density lipoprotein particle IDA IDA IDA IDA IDA IDA IDA IDA
Cellular ComponentGO:0034362low-density lipoprotein particle IDA IDA IDANOT IDA
Cellular ComponentGO:0034363intermediate-density lipoprotein particle IDA IDA IDA
Cellular ComponentGO:0034364high-density lipoprotein particle IDA IDA IDA IDA IDA IDA
Cellular ComponentGO:0034365discoidal high-density lipoprotein particle IDA
Cellular ComponentGO:0034366spherical high-density lipoprotein particle IDA IDA IDA IDA IDA
Cellular ComponentGO:0034774secretory granule lumen TAS
Cellular ComponentGO:0042627chylomicron IBA IDA IDA IDA IDA IDA IDA
Cellular ComponentGO:0043025cell soma NAS
Cellular ComponentGO:0070062extracellular exosome IDA IDA IDA IDA IDA IDA IDA
Cellular ComponentGO:0071682endocytic vesicle lumen TAS TAS
Cellular ComponentGO:0072562blood microparticle IDA IDA IDA IDA IBA
Cellular ComponentGO:1903561extracellular vesicle IDA IDA
Molecular FunctionGO:0001540beta-amyloid binding IDA IDA
Molecular FunctionGO:0005319lipid transporter activity IDA IDA IDA  TAS TAS EXP
Molecular FunctionGO:0005507copper ion binding IDA
Molecular FunctionGO:0005515protein binding IPI IPI IPI IPI IPI
Molecular FunctionGO:0005543phospholipid binding IDA IDA IDA IDA IDA IDA
Molecular FunctionGO:0008047enzyme activator activity IDA
Molecular FunctionGO:0008201heparin binding IDA IDA contributes_to IDA
Molecular FunctionGO:0008289lipid binding IDA IDA IMP IDA IDA
Molecular FunctionGO:0015485cholesterol binding IDA IBA IDA IBA IC IBA
Molecular FunctionGO:0016004phospholipase activator activity IDA
Molecular FunctionGO:0016209antioxidant activity IDA IDA IDA
Molecular FunctionGO:0017127cholesterol transporter activity IMP contributes_to IDA IBAcontributes_to IDA IDA IBA
Molecular FunctionGO:0019899enzyme binding IPI IDA
Molecular FunctionGO:0030234enzyme regulator activity IDA
Molecular FunctionGO:0031210phosphatidylcholine binding IBA IDA IDA IDA
Molecular FunctionGO:0034190apolipoprotein receptor binding IPI IPI
Molecular FunctionGO:0034191apolipoprotein A-I receptor binding IPI
Molecular FunctionGO:0035473lipase binding IPI
Molecular FunctionGO:0042802identical protein binding IPI IDA
Molecular FunctionGO:0042803protein homodimerization activity IDA  IPI IDA IDA IMP
Molecular FunctionGO:0043274phospholipase binding IPI
Molecular FunctionGO:0043499eukaryotic cell surface bindingcontributes_to IDA
Molecular FunctionGO:0045499chemorepellent activity IDA
Molecular FunctionGO:0046911metal chelating activity IDA
Molecular FunctionGO:0046982protein heterodimerization activity IPI IPI IMP
Molecular FunctionGO:0048156tau protein binding IPI
Molecular FunctionGO:0050750low-density lipoprotein receptor binding IDA  IPI IPI
Molecular FunctionGO:0055102lipase inhibitor activity IDA IDA IDA
Molecular FunctionGO:0060228phosphatidylcholine-sterol O-acyltransferas... IDA IDA IDA IDA IBA
Molecular FunctionGO:0060229lipase activator activity IMP
Molecular FunctionGO:0060230lipoprotein lipase activator activity IDA IDA
Molecular FunctionGO:0070325lipoprotein receptor binding IPI IPI
Molecular FunctionGO:0070326very-low-density lipoprotein receptor binding IDA  IPI
Molecular FunctionGO:0070653high-density lipoprotein particle receptor binding IPI IPI IPI
Cellular ComponentGO:0030139endocytic vesicle IDA

Cellular Component graph



RefGenome graph at MGI.


Molecular Function graph



RefGenome graph at MGI.


Biological Process graph



RefGenome graph at MGI.



Pages in category "apolipoproteins involved in RCT"

The following 8 pages are in this category, out of 8 total.