HUMAN:APOA4

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	APOA4
Protein Name(s)	Apolipoprotein A-IV Apo-AIV ApoA-IV Apolipoprotein A4
External Links
UniProt	P06727
EMBL	M13654 M14642 J02758 X13629 AY422950 AY555191 AP006216 BC074764 BC113594 BC113596 M14566
CCDS	CCDS31681.1
PIR	A94137
UniGene	Hs.1247
PDB	3S84
PDBsum	3S84
ProteinModelPortal	P06727
SMR	P06727
DIP	DIP-38333N
IntAct	P06727
STRING	9606.ENSP00000350425
PhosphoSite	P06727
DMDM	93163358
DOSAC-COBS-2DPAGE	P06727
REPRODUCTION-2DPAGE	IPI00304273
SWISS-2DPAGE	P06727
MaxQB	P06727
PaxDb	P06727
PeptideAtlas	P06727
PRIDE	P06727
Ensembl	ENST00000357780
UCSC	uc001pps.1
GeneCards	GC11M116692
HGNC	HGNC:602
HPA	CAB068250 CAB068251 CAB068252 HPA001352 HPA002549
MIM	107690
neXtProt	NX_P06727
eggNOG	NOG42418
HOGENOM	HOG000037942
HOVERGEN	HBG105707
InParanoid	P06727
OrthoDB	EOG7K9K48
PhylomeDB	P06727
TreeFam	TF334458
Reactome	REACT_24968 REACT_6841 REACT_75925
PMAP-CutDB	A8MSL6
PRO	PR:P06727
Proteomes	UP000005640
Bgee	P06727
CleanEx	HS_APOA4
GO	GO:0072562 GO:0042627 GO:0005829 GO:0005769 GO:0005788 GO:0070062 GO:0005576 GO:0005615 GO:0034364 GO:0034361 GO:0016209 GO:0015485 GO:0017127 GO:0005507 GO:0008289 GO:0005319 GO:0031210 GO:0060228 GO:0042803 GO:0006695 GO:0033344 GO:0042632 GO:0008203 GO:0034378 GO:0034371 GO:0034380 GO:0034375 GO:0042744 GO:0002227 GO:0007159 GO:0055088 GO:0006869 GO:0042157 GO:0044240 GO:0034445 GO:0031102 GO:0046470 GO:0033700 GO:0007603 GO:0010873 GO:0045723 GO:0051006 GO:0010898 GO:0065005 GO:0032374 GO:0030300 GO:0019430 GO:0006982 GO:0035634 GO:0001523 GO:0043691 GO:0044281 GO:0019433 GO:0070328 GO:0034372
InterPro	IPR000074
Pfam	PF01442

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005737	cytoplasm		ECO:0000314			C		Source: HPA	Missing: reference
	GO:0005634	nucleus		ECO:0000314			C		Source: HPA	Missing: reference
	GO:0016209	antioxidant activity		ECO:0000314			F		Source: HGNC	Missing: reference
	GO:0005507	copper ion binding		ECO:0000314			F		Source: HGNC	Missing: reference
part_of	GO:0005576	extracellular region	PMID:27068509^[1]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0007318)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:27559042^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0006618) part_of:(UBERON:0002302)	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0072562	blood microparticle	PMID:22516433^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0065005	protein-lipid complex assembly	PMID:16159879^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0055088	lipid homeostasis	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051006	positive regulation of lipoprotein lipase activity	PMID:2307668^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046470	phosphatidylcholine metabolic process	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045723	positive regulation of fatty acid biosynthetic process	PMID:2307668^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016042	lipid catabolic process	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043691	reverse cholesterol transport	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042632	cholesterol homeostasis	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0034445	negative regulation of plasma lipoprotein oxidation	PMID:16945374^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034375	high-density lipoprotein particle remodeling	PMID:1935934^[6]	ECO:0000305	curator inference used in manual assertion	GO:0060228	P		Seeded From UniProt	complete
involved_in	GO:0034372	very-low-density lipoprotein particle remodeling	PMID:2307668^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034371	chylomicron remodeling	PMID:2307668^[8]	ECO:0000305	curator inference used in manual assertion	GO:0051006	P		Seeded From UniProt	complete
part_of	GO:0034364	high-density lipoprotein particle	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0034361	very-low-density lipoprotein particle	PMID:17154273^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0034361	very-low-density lipoprotein particle	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0033700	phospholipid efflux	PMID:11162594^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	PMID:11162594^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032374	regulation of cholesterol transport	PMID:11940599^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031210	phosphatidylcholine binding	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0031210	phosphatidylcholine binding	PMID:11940599^[12]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0017127	cholesterol transporter activity	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0010898	positive regulation of triglyceride catabolic process	PMID:2307668^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010873	positive regulation of cholesterol esterification	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
colocalizes_with	GO:0009986	cell surface	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0008289	lipid binding	PMID:16159879^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0008203	cholesterol metabolic process	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007159	leukocyte cell-cell adhesion	PMID:15254593^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	PMID:3095477^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:20551380^[14]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001496)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:1935934^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002227	innate immune response in mucosa	PMID:15254593^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042744	hydrogen peroxide catabolic process	PMID:16945374^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019430	removal of superoxide radicals	PMID:16945374^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0016209	antioxidant activity	PMID:16945374^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006982	response to lipid hydroperoxide	PMID:16945374^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005507	copper ion binding	PMID:16945374^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	PMID:14718574^[15]	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0070328	triglyceride homeostasis	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439035 UniProtKB:Q6Q788	P		Seeded From UniProt	complete
enables	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88057 PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727	F		Seeded From UniProt	complete
involved_in	GO:0051006	positive regulation of lipoprotein lipase activity	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439035 UniProtKB:P06727 UniProtKB:Q6Q788	P		Seeded From UniProt	complete
involved_in	GO:0046889	positive regulation of lipid biosynthetic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:P02649	P		Seeded From UniProt	complete
involved_in	GO:0046470	phosphatidylcholine metabolic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439035 UniProtKB:P06727	P		Seeded From UniProt	complete
involved_in	GO:0045723	positive regulation of fatty acid biosynthetic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439035 UniProtKB:P06727 UniProtKB:Q6Q788	P		Seeded From UniProt	complete
involved_in	GO:0043691	reverse cholesterol transport	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727	P		Seeded From UniProt	complete
involved_in	GO:0042632	cholesterol homeostasis	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88057 PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727 UniProtKB:Q6Q788	P		Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 RGD:2132 RGD:2138 UniProtKB:P02649 UniProtKB:P06727 UniProtKB:Q6Q788	C		Seeded From UniProt	complete
involved_in	GO:0042157	lipoprotein metabolic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88057 PANTHER:PTN000439006 RGD:2138	P		Seeded From UniProt	complete
involved_in	GO:0034380	high-density lipoprotein particle assembly	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649	P		Seeded From UniProt	complete
involved_in	GO:0034372	very-low-density lipoprotein particle remodeling	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88057 PANTHER:PTN000439006 UniProtKB:P02649 UniProtKB:P06727	P		Seeded From UniProt	complete
part_of	GO:0034364	high-density lipoprotein particle	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 RGD:2130 RGD:2138 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727 UniProtKB:Q6Q788	C		Seeded From UniProt	complete
involved_in	GO:0033700	phospholipid efflux	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727	P		Seeded From UniProt	complete
involved_in	GO:0033344	cholesterol efflux	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88049 MGI:MGI:88057 PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727	P		Seeded From UniProt	complete
involved_in	GO:0032374	regulation of cholesterol transport	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:P06727	P		Seeded From UniProt	complete
enables	GO:0031210	phosphatidylcholine binding	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439035 UniProtKB:P06727 UniProtKB:Q6Q788	F		Seeded From UniProt	complete
involved_in	GO:0030300	regulation of intestinal cholesterol absorption	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88051 PANTHER:PTN000439035	P		Seeded From UniProt	complete
involved_in	GO:0019433	triglyceride catabolic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:Q6Q788	P		Seeded From UniProt	complete
enables	GO:0017127	cholesterol transporter activity	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88049 MGI:MGI:88057 PANTHER:PTN000439006 RGD:2130 UniProtKB:P02647 UniProtKB:P06727	F		Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 UniProtKB:P02647	F		Seeded From UniProt	complete
involved_in	GO:0010898	positive regulation of triglyceride catabolic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439035 UniProtKB:P06727 UniProtKB:Q6Q788	P		Seeded From UniProt	complete
involved_in	GO:0010873	positive regulation of cholesterol esterification	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88057 PANTHER:PTN000439006 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:P06727	P		Seeded From UniProt	complete
involved_in	GO:0006695	cholesterol biosynthetic process	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88049 PANTHER:PTN000439006	P		Seeded From UniProt	complete
enables	GO:0005543	phospholipid binding	PMID:21873635^[16]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000439006 RGD:2138 UniProtKB:P02647 UniProtKB:P02649 UniProtKB:Q6Q788	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:22579246^[17]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P06727	F		Seeded From UniProt	complete
involved_in	GO:0035634	response to stilbenoid	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06728 ensembl:ENSMUSP00000034585	P		Seeded From UniProt	complete
involved_in	GO:0030300	regulation of intestinal cholesterol absorption	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06728 ensembl:ENSMUSP00000034585	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06728 ensembl:ENSMUSP00000034585	C		Seeded From UniProt	complete
involved_in	GO:0002227	innate immune response in mucosa	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06728 ensembl:ENSMUSP00000034585	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000074	C		Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000074	P		Seeded From UniProt	complete
enables	GO:0008289	lipid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000074	F		Seeded From UniProt	complete
involved_in	GO:0042157	lipoprotein metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000074	P		Seeded From UniProt	complete
enables	GO:0005319	lipid transporter activity	PMID:3080432^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0034378	chylomicron assembly	PMID:16159879^[5] Reactome:R-HSA-8963888	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0044267	cellular protein metabolic process	Reactome:R-HSA-392499	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034371	chylomicron remodeling	Reactome:R-HSA-8963901	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-2395764 Reactome:R-HSA-2187332	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005788	endoplasmic reticulum lumen	Reactome:R-HSA-174741 Reactome:R-HSA-174587	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	Reactome:R-HSA-2429643 Reactome:R-HSA-2404140 Reactome:R-HSA-2404131	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-HSA-977136 Reactome:R-HSA-976734 Reactome:R-HSA-2423785 Reactome:R-HSA-2404131 Reactome:R-HSA-2395784 Reactome:R-HSA-2395768 Reactome:R-HSA-2187332 Reactome:R-HSA-174757 Reactome:R-HSA-174690 Reactome:R-HSA-174660 Reactome:R-HSA-174587	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0001523	retinoid metabolic process	Reactome:R-HSA-975634	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0162	C		Seeded From UniProt	complete
part_of	GO:0034364	high-density lipoprotein particle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0345	C		Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0445	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Barallobre-Barreiro, J et al. (2016) Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins. Cardiovasc. Res. 110 419-30 PubMed GONUTS page
↑ Barallobre-Barreiro, J et al. (2016) Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation 134 817-32 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ Bastos-Amador, P et al. (2012) Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. J Proteomics 75 3574-84 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Pearson, K et al. (2005) Specific sequences in the N and C termini of apolipoprotein A-IV modulate its conformation and lipid association. J. Biol. Chem. 280 38576-82 PubMed GONUTS page
↑ ^6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 Duverger, N et al. (1991) Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli. Eur. J. Biochem. 201 373-83 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 ^7.6 Ghiselli, G et al. (1986) Plasma metabolism of apolipoprotein A-IV in humans. J. Lipid Res. 27 813-27 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Goldberg, IJ et al. (1990) Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV. J. Biol. Chem. 265 4266-72 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 ^9.4 ^9.5 Wong, WM et al. (2007) Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation. Atherosclerosis 192 266-74 PubMed GONUTS page
↑ Mancone, C et al. (2007) Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF. Proteomics 7 143-54 PubMed GONUTS page
↑ ^11.0 ^11.1 Remaley, AT et al. (2001) Apolipoprotein specificity for lipid efflux by the human ABCAI transporter. Biochem. Biophys. Res. Commun. 280 818-23 PubMed GONUTS page
↑ ^12.0 ^12.1 Weinberg, RB et al. (2002) Interfacial exclusion pressure determines the ability of apolipoprotein A-IV truncation mutants to activate cholesterol ester transfer protein. J. Biol. Chem. 277 21549-53 PubMed GONUTS page
↑ ^13.0 ^13.1 Vowinkel, T et al. (2004) Apolipoprotein A-IV inhibits experimental colitis. J. Clin. Invest. 114 260-9 PubMed GONUTS page
↑ Didangelos, A et al. (2010) Proteomics characterization of extracellular space components in the human aorta. Mol. Cell Proteomics 9 2048-62 PubMed GONUTS page
↑ Anderson, NL et al. (2004) The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol. Cell Proteomics 3 311-26 PubMed GONUTS page
↑ ^16.00 ^16.01 ^16.02 ^16.03 ^16.04 ^16.05 ^16.06 ^16.07 ^16.08 ^16.09 ^16.10 ^16.11 ^16.12 ^16.13 ^16.14 ^16.15 ^16.16 ^16.17 ^16.18 ^16.19 ^16.20 ^16.21 ^16.22 ^16.23 ^16.24 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Deng, X et al. (2012) The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Structure 20 767-79 PubMed GONUTS page
↑ Elshourbagy, NA et al. (1986) The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III. J. Biol. Chem. 261 1998-2002 PubMed GONUTS page

[PMID:27068509-1] Barallobre-Barreiro, J et al. (2016) Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins. Cardiovasc. Res. 110 419-30 PubMed GONUTS page

[PMID:27559042-2] Barallobre-Barreiro, J et al. (2016) Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation 134 817-32 PubMed GONUTS page

[PMID:23533145-3] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:22516433-4] Bastos-Amador, P et al. (2012) Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. J Proteomics 75 3574-84 PubMed GONUTS page

[PMID:16159879-5] 5.0 ^5.1 ^5.2 Pearson, K et al. (2005) Specific sequences in the N and C termini of apolipoprotein A-IV modulate its conformation and lipid association. J. Biol. Chem. 280 38576-82 PubMed GONUTS page

[PMID:1935934-6] 6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 Duverger, N et al. (1991) Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli. Eur. J. Biochem. 201 373-83 PubMed GONUTS page

[PMID:3095477-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 ^7.6 Ghiselli, G et al. (1986) Plasma metabolism of apolipoprotein A-IV in humans. J. Lipid Res. 27 813-27 PubMed GONUTS page

[PMID:2307668-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Goldberg, IJ et al. (1990) Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV. J. Biol. Chem. 265 4266-72 PubMed GONUTS page

[PMID:16945374-9] 9.0 ^9.1 ^9.2 ^9.3 ^9.4 ^9.5 Wong, WM et al. (2007) Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation. Atherosclerosis 192 266-74 PubMed GONUTS page

[PMID:17154273-10] Mancone, C et al. (2007) Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF. Proteomics 7 143-54 PubMed GONUTS page

[PMID:11162594-11] 11.0 ^11.1 Remaley, AT et al. (2001) Apolipoprotein specificity for lipid efflux by the human ABCAI transporter. Biochem. Biophys. Res. Commun. 280 818-23 PubMed GONUTS page

[PMID:11940599-12] 12.0 ^12.1 Weinberg, RB et al. (2002) Interfacial exclusion pressure determines the ability of apolipoprotein A-IV truncation mutants to activate cholesterol ester transfer protein. J. Biol. Chem. 277 21549-53 PubMed GONUTS page

[PMID:15254593-13] 13.0 ^13.1 Vowinkel, T et al. (2004) Apolipoprotein A-IV inhibits experimental colitis. J. Clin. Invest. 114 260-9 PubMed GONUTS page

[PMID:20551380-14] Didangelos, A et al. (2010) Proteomics characterization of extracellular space components in the human aorta. Mol. Cell Proteomics 9 2048-62 PubMed GONUTS page

[PMID:14718574-15] Anderson, NL et al. (2004) The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol. Cell Proteomics 3 311-26 PubMed GONUTS page

[PMID:21873635-16] 16.00 ^16.01 ^16.02 ^16.03 ^16.04 ^16.05 ^16.06 ^16.07 ^16.08 ^16.09 ^16.10 ^16.11 ^16.12 ^16.13 ^16.14 ^16.15 ^16.16 ^16.17 ^16.18 ^16.19 ^16.20 ^16.21 ^16.22 ^16.23 ^16.24 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:22579246-17] Deng, X et al. (2012) The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Structure 20 767-79 PubMed GONUTS page

[PMID:3080432-18] Elshourbagy, NA et al. (1986) The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III. J. Biol. Chem. 261 1998-2002 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

HUMAN:APOA4

Contents

Annotations

Notes

References

a

b

c

e

h

i

l

m

n

o

p

r

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools