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Category:GO:1990851 ! Wnt-Frizzled-LRP5/6 complex
name: Wnt-Frizzled-LRP5/6 complex
namespace: cellular_component
def: "A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6." [GOC:bf, GOC:PARL, PMID:11448771, PMID:20093360]
comment: Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form.
synonym: "Frizzled-LRP5/6 complex" RELATED [GOC:bf]
synonym: "Fz/Wnt/LRP6 complex" NARROW [PMID:20093360]
synonym: "Wnt receptor complex" BROAD [GOC:bf]
synonym: "WNT-FZD-LRP5 complex" NARROW [PMID:23209147]
synonym: "Wnt-FZD-LRP5/6 trimeric complex" EXACT [PMID:23209147]
synonym: "WNT-FZD-LRP6 complex" NARROW [PMID:23209147]
synonym: "Wnt-induced Frizzled-LRP5/6 complex" RELATED [GOC:bf]
synonym: "Wnt.Fz.LRP ternary complex" EXACT [PMID:20093360]
is_a: GO:0098797 ! plasma membrane protein complex
AmiGO
<GOterm>GO:1990851</GOterm>
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