HUMAN:WNT3A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	WNT3A
Protein Name(s)	Protein Wnt-3a
External Links
UniProt	P56704
EMBL	AB060284 AK056278 AL136379 BC103921 BC103922 BC103923
CCDS	CCDS1564.1
RefSeq	NP_149122.1
UniGene	Hs.336930
ProteinModelPortal	P56704
SMR	P56704
BioGrid	124599
DIP	DIP-58592N
IntAct	P56704
STRING	9606.ENSP00000284523
BindingDB	P56704
ChEMBL	CHEMBL1255137
PhosphoSite	P56704
DMDM	20532424
PaxDb	P56704
PRIDE	P56704
Ensembl	ENST00000284523
GeneID	89780
KEGG	hsa:89780
UCSC	uc001hrp.2 uc001hrq.2
CTD	89780
GeneCards	GC01P228194
HGNC	HGNC:15983
HPA	HPA050514
MIM	606359
neXtProt	NX_P56704
Orphanet	85193
PharmGKB	PA38074
eggNOG	NOG284879
GeneTree	ENSGT00760000118943
HOGENOM	HOG000039529
HOVERGEN	HBG001595
InParanoid	P56704
KO	K00312
OMA	CTTVNDS
OrthoDB	EOG7C8GJ8
PhylomeDB	P56704
TreeFam	TF105310
Reactome	REACT_163710 REACT_18372 REACT_200610 REACT_200643 REACT_200716 REACT_200777 REACT_228188
SignaLink	P56704
GeneWiki	WNT3A
GenomeRNAi	89780
NextBio	76263
PRO	PR:P56704
Proteomes	UP000005640
Bgee	P56704
CleanEx	HS_WNT3A
Genevestigator	P56704
GO	GO:0009986 GO:0005788 GO:0005576 GO:0005615 GO:0005796 GO:0005886 GO:0005578 GO:0005109 GO:0048018 GO:0003713 GO:0090245 GO:0007411 GO:0060070 GO:0061317 GO:0021846 GO:0034613 GO:0071300 GO:0010387 GO:0021904 GO:0030198 GO:0001947 GO:0030097 GO:0021766 GO:0001701 GO:0042472 GO:0030879 GO:0048843 GO:0045599 GO:0003136 GO:0050768 GO:0010977 GO:0030182 GO:0001649 GO:0060021 GO:0048343 GO:0070527 GO:0030890 GO:0090263 GO:2000081 GO:2000727 GO:0035413 GO:0008284 GO:2000049 GO:0048697 GO:0043280 GO:0061184 GO:0048337 GO:0033138 GO:0032092 GO:0001934 GO:0061098 GO:0002092 GO:0051091 GO:0045944 GO:0045893 GO:0036342 GO:0070507 GO:0035914 GO:0021527 GO:0021874
InterPro	IPR005817 IPR009141 IPR018161
PANTHER	PTHR12027
Pfam	PF00110
PRINTS	PR01843 PR01349
SMART	SM00097
PROSITE	PS00246

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	PMID:20723538^[1]	ECO:0000314			P		Figure 1A: Wnt3a increased the total beta-catenin level in HEK293A cells indicating that Wnt3a activates the canonical pathway in the particular cells.	complete
	GO:0035413	positive regulation of catenin protein nuclear translocation	PMID:20723538^[1]	ECO:0000314			P		Figure 1B: induction of beta-catenin protein level upon Wnt3a/sFRP2 showed increased beta-catenin nuclear translocation	complete
	GO:0017025	TATA-binding protein binding	PMID:20723538^[1]	ECO:0000314			F		Figure 1(B): Wnt3a binds to TATA binding protein.	complete
	GO:0001934	positive regulation of protein phosphorylation	PMID:20723538^[1]	ECO:0000314			P		Figure 1(D): Treatment with Wnt3a lead to induced phosphorylation of LRP6. In addition, treatment with both the Wnt3a and sFRP2 enhanced the LRP6 phosphorylation in HEK293A cells.	complete
	GO:0045941	positive regulation of transcription	PMID:20723538^[1]	ECO:0000314			P		Figure 3:When Wnt3a plus sFRP2 were used for treatment of Wnt11 showed enhanced mRNA expression.	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:26902720^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	PMID:26902720^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:26902720^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:26687115^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_expression_of:(ENSEMBL:ENSG00000168646)	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P	regulates_transcription_of:(ENSEMBL:ENSG00000006283)	Seeded From UniProt	complete
enables	GO:0048018	receptor ligand activity	PMID:28733458^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:28733458^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:1990851	Wnt-Frizzled-LRP5/6 complex	PMID:20093360^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:20093360^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q61091	F		Seeded From UniProt	complete
enables	GO:0039706	co-receptor binding	PMID:20093360^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O75581	F		Seeded From UniProt	complete
involved_in	GO:2000727	positive regulation of cardiac muscle cell differentiation	PMID:20559569^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	PMID:20559569^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061184	positive regulation of dermatome development	PMID:10654605^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:19101069^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:20137080^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:20723538^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0062009	secondary palate development	PMID:18413325^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050768	negative regulation of neurogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P		Seeded From UniProt	complete
involved_in	GO:0048337	positive regulation of mesodermal cell fate specification	PMID:20559569^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0048018	receptor ligand activity	PMID:20723538^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:20723538^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P		Seeded From UniProt	complete
involved_in	GO:0090263	positive regulation of canonical Wnt signaling pathway	PMID:20723538^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090263	positive regulation of canonical Wnt signaling pathway	PMID:20137080^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033138	positive regulation of peptidyl-serine phosphorylation	PMID:20723538^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032092	positive regulation of protein binding	PMID:16890161^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021846	cell proliferation in forebrain	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P		Seeded From UniProt	complete
involved_in	GO:0010387	COP9 signalosome assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	C		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	C		Seeded From UniProt	complete
involved_in	GO:0003136	negative regulation of heart induction by canonical Wnt signaling pathway	PMID:19736317^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002092	positive regulation of receptor internalization	PMID:16890161^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:20137080^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:20412773^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:18941195^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071300	cellular response to retinoic acid	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P56706	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P56706	P		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P27467	P		Seeded From UniProt	complete
involved_in	GO:1905606	regulation of presynapse assembly	PMID:19883499^[15]	ECO:0006063	over expression analysis evidence used in manual assertion		P	occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:1905606	regulation of presynapse assembly	PMID:19883499^[15]	ECO:0005589	confocal microscopy evidence used in manual assertion		P	occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:18986540^[16]	ECO:0006063	over expression analysis evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:18986540^[16]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:18986540^[16]	ECO:0006063	over expression analysis evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:18986540^[16]	ECO:0005589	confocal microscopy evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000061) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0045165	cell fate commitment	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98957 PANTHER:PTN000246517 UniProtKB:P49339 ZFIN:ZDB-GENE-980526-332	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000246517 RGD:69250 UniProtKB:P56706 UniProtKB:Q98SN7	P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010194 MGI:MGI:108061 MGI:MGI:1197020 MGI:MGI:98953 MGI:MGI:98954 MGI:MGI:98956 MGI:MGI:98958 MGI:MGI:98960 MGI:MGI:98961 MGI:MGI:98962 PANTHER:PTN000246517 UniProtKB:P41221 UniProtKB:Q98SN7 WB:WBGene00000858 WB:WBGene00003029 ZFIN:ZDB-GENE-980526-332	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004009 MGI:MGI:98956 MGI:MGI:98957 PANTHER:PTN000246517 RGD:1311441 RGD:69250 UniProtKB:P41221 UniProtKB:P56704 UniProtKB:P56705 UniProtKB:Q2LMP1 UniProtKB:Q9UBV4 UniProtKB:Q9YGX6	C		Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004009 FB:FBgn0004360 FB:FBgn0010453 FB:FBgn0038134 MGI:MGI:98956 MGI:MGI:98957 MGI:MGI:98958 MGI:MGI:98961 MGI:MGI:98962 PANTHER:PTN000246517 RGD:69079 UniProtKB:P09544 UniProtKB:P41221 UniProtKB:P56703 UniProtKB:Q98SN7	F		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	PMID:23797875^[18]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0048018	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048018	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048018	P		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0036465	C		Seeded From UniProt	complete
involved_in	GO:2001141	regulation of RNA biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:2000347	positive regulation of hepatocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:2000179	positive regulation of neural precursor cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:2000081	positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:1904798	positive regulation of core promoter binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:1904339	negative regulation of dopaminergic neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:1903078	positive regulation of protein localization to plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:1901215	negative regulation of neuron death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0099527	postsynapse to nucleus signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	C		Seeded From UniProt	complete
involved_in	GO:0090676	calcium ion transmembrane transport via low voltage-gated calcium channel	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0090263	positive regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0090245	axis elongation involved in somitogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0070527	platelet aggregation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0070507	regulation of microtubule cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0061098	positive regulation of protein tyrosine kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0060923	cardiac muscle cell fate commitment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0060070	canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0051091	positive regulation of DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0050804	modulation of chemical synaptic transmission	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0050770	regulation of axonogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0050768	negative regulation of neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0048843	negative regulation of axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0048697	positive regulation of collateral sprouting in absence of injury	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0048643	positive regulation of skeletal muscle tissue development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0048343	paraxial mesodermal cell fate commitment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0048103	somatic stem cell division	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
enables	GO:0048018	receptor ligand activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0045860	positive regulation of protein kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0045599	negative regulation of fat cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0045595	regulation of cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	C		Seeded From UniProt	complete
involved_in	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0042472	inner ear morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0036342	post-anal tail morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0035914	skeletal muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0034613	cellular protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0033278	cell proliferation in midbrain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0030901	midbrain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0030890	positive regulation of B cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0030879	mammary gland development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0030198	extracellular matrix organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0030168	platelet activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0030097	hemopoiesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0022008	neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0021904	dorsal/ventral neural tube patterning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0021874	Wnt signaling pathway involved in forebrain neuroblast division	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0021846	cell proliferation in forebrain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0021766	hippocampus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0021527	spinal cord association neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	F		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0010977	negative regulation of neuron projection development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0010387	COP9 signalosome assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	C		Seeded From UniProt	complete
involved_in	GO:0009952	anterior/posterior pattern specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0007498	mesoderm development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0007409	axonogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0007368	determination of left/right symmetry	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	C		Seeded From UniProt	complete
enables	GO:0005109	frizzled binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	F		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	F		Seeded From UniProt	complete
involved_in	GO:0001947	heart looping	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0001819	positive regulation of cytokine production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0001701	in utero embryonic development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
involved_in	GO:0001649	osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27467 ensembl:ENSMUSP00000010044	P		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009141	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009141	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009141	P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005817 InterPro:IPR009141	P		Seeded From UniProt	complete
involved_in	GO:0099054	presynapse assembly	PMID:24449494^[19]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033278	cell proliferation in midbrain	PMID:24431302^[20]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	PMID:22988876^[21]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0036465	synaptic vesicle recycling	PMID:22988876^[21]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	occurs_at:(GO:0098793)	Seeded From UniProt	complete
involved_in	GO:1904886	beta-catenin destruction complex disassembly	Reactome:R-HSA-4641262	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	Reactome:R-HSA-3781941	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031901	early endosome membrane	Reactome:R-HSA-5368596	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030666	endocytic vesicle membrane	Reactome:R-HSA-3781943 Reactome:R-HSA-3781941	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	Reactome:R-HSA-195721	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-3781943 Reactome:R-HSA-3247844 Reactome:R-HSA-3247843	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005796	Golgi lumen	Reactome:R-HSA-3247844 Reactome:R-HSA-3247840 Reactome:R-HSA-3247837	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005788	endoplasmic reticulum lumen	Reactome:R-HSA-3247837	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-NUL-1458902 Reactome:R-HSA-5368596 Reactome:R-HSA-5340587 Reactome:R-HSA-5323545 Reactome:R-HSA-4641253 Reactome:R-HSA-4641249 Reactome:R-HSA-4641236 Reactome:R-HSA-3247843 Reactome:R-HSA-201677 Reactome:R-HSA-1504186	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0879	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 von Marschall, Z & Fisher, LW (2010) Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling. Biochem. Biophys. Res. Commun. 400 299-304 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Mihara, E et al. (2016) Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin. Elife 5 PubMed GONUTS page
↑ Le, LT et al. (2016) The microRNA-29 family in cartilage homeostasis and osteoarthritis. J. Mol. Med. 94 583-96 PubMed GONUTS page
↑ ^4.0 ^4.1 Voloshanenko, O et al. (2017) Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families. FASEB J. 31 4832-4844 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Bourhis, E et al. (2010) Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. J. Biol. Chem. 285 9172-9 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Paige, SL et al. (2010) Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS ONE 5 e11134 PubMed GONUTS page
↑ Lee, CS et al. (2000) SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm. Development 127 109-18 PubMed GONUTS page
↑ Nygren, MK et al. (2009) beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells. Exp. Hematol. 37 225-33 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Gnad, T et al. (2010) Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled. Mol. Cancer 9 31 PubMed GONUTS page
↑ Chiquet, BT et al. (2008) Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. Hum. Mol. Genet. 17 2212-8 PubMed GONUTS page
↑ ^11.0 ^11.1 Yamamoto, H et al. (2006) Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev. Cell 11 213-23 PubMed GONUTS page
↑ Stefanovic, S et al. (2009) Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate. J. Cell Biol. 186 665-73 PubMed GONUTS page
↑ Varelas, X et al. (2010) The Hippo pathway regulates Wnt/beta-catenin signaling. Dev. Cell 18 579-91 PubMed GONUTS page
↑ Yokota, T et al. (2008) Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis. J. Immunol. 181 6061-72 PubMed GONUTS page
↑ ^15.0 ^15.1 Varela-Nallar, L et al. (2009) Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function. Neural Dev 4 41 PubMed GONUTS page
↑ ^16.0 ^16.1 ^16.2 ^16.3 Davis, EK et al. (2008) Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation. Neural Dev 3 32 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 ^17.3 ^17.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Serysheva, E et al. (2013) Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling. EMBO Rep. 14 718-25 PubMed GONUTS page
↑ Purro, SA et al. (2014) Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases. J Mol Cell Biol 6 75-80 PubMed GONUTS page
↑ Arenas, E (2014) Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease. J Mol Cell Biol 6 42-53 PubMed GONUTS page
↑ ^21.0 ^21.1 Berwick, DC & Harvey, K (2012) The importance of Wnt signalling for neurodegeneration in Parkinson's disease. Biochem. Soc. Trans. 40 1123-8 PubMed GONUTS page

[PMID:20723538-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 von Marschall, Z & Fisher, LW (2010) Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling. Biochem. Biophys. Res. Commun. 400 299-304 PubMed GONUTS page

[PMID:26902720-2] 2.0 ^2.1 ^2.2 Mihara, E et al. (2016) Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin. Elife 5 PubMed GONUTS page

[PMID:26687115-3] Le, LT et al. (2016) The microRNA-29 family in cartilage homeostasis and osteoarthritis. J. Mol. Med. 94 583-96 PubMed GONUTS page

[PMID:28733458-4] 4.0 ^4.1 Voloshanenko, O et al. (2017) Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families. FASEB J. 31 4832-4844 PubMed GONUTS page

[PMID:20093360-5] 5.0 ^5.1 ^5.2 Bourhis, E et al. (2010) Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6. J. Biol. Chem. 285 9172-9 PubMed GONUTS page

[PMID:20559569-6] 6.0 ^6.1 ^6.2 Paige, SL et al. (2010) Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS ONE 5 e11134 PubMed GONUTS page

[PMID:10654605-7] Lee, CS et al. (2000) SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm. Development 127 109-18 PubMed GONUTS page

[PMID:19101069-8] Nygren, MK et al. (2009) beta-catenin is involved in N-cadherin-dependent adhesion, but not in canonical Wnt signaling in E2A-PBX1-positive B acute lymphoblastic leukemia cells. Exp. Hematol. 37 225-33 PubMed GONUTS page

[PMID:20137080-9] 9.0 ^9.1 ^9.2 Gnad, T et al. (2010) Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled. Mol. Cancer 9 31 PubMed GONUTS page

[PMID:18413325-10] Chiquet, BT et al. (2008) Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. Hum. Mol. Genet. 17 2212-8 PubMed GONUTS page

[PMID:16890161-11] 11.0 ^11.1 Yamamoto, H et al. (2006) Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev. Cell 11 213-23 PubMed GONUTS page

[PMID:19736317-12] Stefanovic, S et al. (2009) Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate. J. Cell Biol. 186 665-73 PubMed GONUTS page

[PMID:20412773-13] Varelas, X et al. (2010) The Hippo pathway regulates Wnt/beta-catenin signaling. Dev. Cell 18 579-91 PubMed GONUTS page

[PMID:18941195-14] Yokota, T et al. (2008) Soluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesis. J. Immunol. 181 6061-72 PubMed GONUTS page

[PMID:19883499-15] 15.0 ^15.1 Varela-Nallar, L et al. (2009) Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function. Neural Dev 4 41 PubMed GONUTS page

[PMID:18986540-16] 16.0 ^16.1 ^16.2 ^16.3 Davis, EK et al. (2008) Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation. Neural Dev 3 32 PubMed GONUTS page

[PMID:21873635-17] 17.0 ^17.1 ^17.2 ^17.3 ^17.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:23797875-18] Serysheva, E et al. (2013) Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling. EMBO Rep. 14 718-25 PubMed GONUTS page

[PMID:24449494-19] Purro, SA et al. (2014) Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases. J Mol Cell Biol 6 75-80 PubMed GONUTS page

[PMID:24431302-20] Arenas, E (2014) Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease. J Mol Cell Biol 6 42-53 PubMed GONUTS page

[PMID:22988876-21] 21.0 ^21.1 Berwick, DC & Harvey, K (2012) The importance of Wnt signalling for neurodegeneration in Parkinson's disease. Biochem. Soc. Trans. 40 1123-8 PubMed GONUTS page

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HUMAN:WNT3A

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