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Category:GO:0038180 ! nerve growth factor signaling pathway
name: nerve growth factor signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by nerve growth factor (NGF) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." [GOC:bf, PMID:11520933]
comment: Nerve growth factor (NGF) binds at least two classes of receptors: the p75 LNGFR (low-affinity nerve growth factor receptor) and TrkA, a transmembrane tyrosine kinase.
synonym: "nerve growth factor signalling pathway" EXACT [GOC:bf]
synonym: "NGF signaling pathway" EXACT [PR:000011194, Wikipedia:Nerve_growth_factor]
xref: Wikipedia:Nerve_growth_factor
is_a: GO:0038179 ! neurotrophin signaling pathway
relationship: part_of: GO:1990090 ! cellular response to nerve growth factor stimulus
AmiGO
<GOterm>GO:0038180</GOterm>
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