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CHICK:BDNF

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) BDNF
Protein Name(s) Brain-derived neurotrophic factor

BDNF

External Links
UniProt P25429
EMBL M83377
DQ124361
X61476
PIR I50606
RefSeq NP_001026787.1
UniGene Gga.696
ProteinModelPortal P25429
SMR P25429
STRING 9031.ENSGALP00000019837
PaxDb P25429
Ensembl ENSGALT00000019864
GeneID 396186
KEGG gga:396186
CTD 627
eggNOG NOG45248
GeneTree ENSGT00390000007725
HOGENOM HOG000231516
HOVERGEN HBG006494
InParanoid P25429
KO K04355
OMA RVGWRFI
OrthoDB EOG7RBZ8Z
PhylomeDB P25429
TreeFam TF106463
NextBio 20816238
PRO PR:P25429
Proteomes UP000000539
ExpressionAtlas P25429
GO GO:0005737
GO:0016023
GO:0005576
GO:0048471
GO:0008083
GO:0005169
GO:0048675
GO:0007411
GO:0007412
GO:0001662
GO:0031547
GO:0007267
GO:0016358
GO:0097484
GO:0007631
GO:0007214
GO:0014047
GO:0048839
GO:0007611
GO:0042490
GO:0007406
GO:0043524
GO:0032229
GO:0021675
GO:0048812
GO:0008038
GO:0048672
GO:0051965
GO:0060080
GO:0019222
GO:0045664
GO:0046668
GO:0048167
GO:0042493
GO:0061193
GO:0007169
GO:0001657
Gene3D 2.10.90.10
InterPro IPR020430
IPR029034
IPR020408
IPR002072
IPR019846
PANTHER PTHR11589
Pfam PF00243
PIRSF PIRSF001789
PRINTS PR01912
PR00268
ProDom PD002052
SMART SM00140
SUPFAM SSF57501
PROSITE PS00248
PS50270

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005634

nucleus

PMID:19046370[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0001928)

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:19046370[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0001928)

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P21237

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P21237

C

Seeded From UniProt

complete

involved_in

GO:0050804

modulation of chemical synaptic transmission

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000904283
RGD:619728

P

Seeded From UniProt

complete

involved_in

GO:0048812

neuron projection morphogenesis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000904283
UniProtKB:P01138

P

Seeded From UniProt

complete

involved_in

GO:0045664

regulation of neuron differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97321
PANTHER:PTN000904283

P

Seeded From UniProt

complete

involved_in

GO:0043524

negative regulation of neuron apoptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88145
MGI:MGI:97321
MGI:MGI:97380
PANTHER:PTN000904283
RGD:1598328

P

Seeded From UniProt

complete

involved_in

GO:0038180

nerve growth factor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97321
PANTHER:PTN000904283

P

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88145
MGI:MGI:97380
PANTHER:PTN000904283

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88145
PANTHER:PTN000904283
RGD:2202

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88145
PANTHER:PTN000904283
RGD:2202

C

Seeded From UniProt

complete

involved_in

GO:0021675

nerve development

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88145
MGI:MGI:97380
PANTHER:PTN000904283

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000904283
UniProtKB:P20783

F

Seeded From UniProt

complete

part_of

GO:0008021

synaptic vesicle

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000904283
RGD:2202

C

Seeded From UniProt

complete

involved_in

GO:0007613

memory

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000173497
RGD:1598328

P

Seeded From UniProt

complete

involved_in

GO:0007422

peripheral nervous system development

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97321
MGI:MGI:97380
PANTHER:PTN000904283

P

Seeded From UniProt

complete

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000904283
UniProtKB:P20783

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000904283
RGD:1598328
RGD:2202

C

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002072

F

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Yossifoff, M et al. (2008) Dynamic changes in DNA methylation during thermal control establishment affect CREB binding to the brain-derived neurotrophic factor promoter. Eur. J. Neurosci. 28 2267-77 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page