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Category:GO:0016082 ! synaptic vesicle priming
name: synaptic vesicle priming
namespace: biological_process
def: "A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane." [GOC:mah, PMID:15217342, PMID:23060190]
comment: Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission. (dos, pvn, fk synapse project 2015)
subset: goslim_synapse
is_a: GO:0065003 ! protein-containing complex assembly
is_a: GO:0140029 ! exocytic process
relationship: part_of: GO:0016079 ! synaptic vesicle exocytosis
AmiGO
<GOterm>GO:0016082</GOterm>
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