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Category:GO:0008626 ! granzyme-mediated apoptotic signaling pathway
name: granzyme-mediated apoptotic signaling pathway
namespace: biological_process
def: "The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells." [GOC:mtg_apoptosis, PMID:17158907]
synonym: "apoptotic signaling pathway in response to granzyme" RELATED []
synonym: "induction of apoptosis by granzyme" RELATED []
is_a: GO:0097190 ! apoptotic signaling pathway
is_a: GO:0140507 ! granzyme-mediated programmed cell death signaling pathway
AmiGO
<GOterm>GO:0008626</GOterm>
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