HUMAN:LAMP1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	LAMP1
Protein Name(s)	Lysosome-associated membrane glycoprotein 1 LAMP-1 Lysosome-associated membrane protein 1 CD107 antigen-like family member A
External Links
UniProt	P11279
EMBL	J04182 AK301584 AL136221 CH471085 BC006345 BC007845 BC021288 BC093044 J03263 AH003113
CCDS	CCDS41909.1
PIR	A31959
RefSeq	NP_005552.3
UniGene	Hs.494419
ProteinModelPortal	P11279
SMR	P11279
BioGrid	110110
IntAct	P11279
MINT	MINT-3007678
STRING	9606.ENSP00000333298
TCDB	9.A.16.1.1
PhosphoSite	P11279
UniCarbKB	P11279
DMDM	206729915
MaxQB	P11279
PaxDb	P11279
PRIDE	P11279
DNASU	3916
Ensembl	ENST00000332556
GeneID	3916
KEGG	hsa:3916
UCSC	uc001vtm.1
CTD	3916
GeneCards	GC13P113951
H-InvDB	HIX0030831
HGNC	HGNC:6499
HPA	CAB004260 HPA014750
MIM	153330
neXtProt	NX_P11279
PharmGKB	PA30283
eggNOG	NOG301998
GeneTree	ENSGT00530000063068
HOGENOM	HOG000230942
HOVERGEN	HBG052303
InParanoid	P11279
KO	K06528
OMA	GTACIMA
OrthoDB	EOG7ZD1VH
PhylomeDB	P11279
TreeFam	TF316339
ChiTaRS	LAMP1
GeneWiki	LAMP1
GenomeRNAi	3916
NextBio	15385
PRO	PR:P11279
Proteomes	UP000005640
Bgee	P11279
CleanEx	HS_LAMP1
ExpressionAtlas	P11279
Genevestigator	P11279
GO	GO:0097208 GO:0044194 GO:0005737 GO:0030425 GO:0010008 GO:0009897 GO:0070062 GO:0005887 GO:0005770 GO:0005764 GO:0042470 GO:0016020 GO:0005771 GO:0043025 GO:0061474 GO:0005886 GO:0042383 GO:0019899 GO:0048102 GO:0006914 GO:0072594 GO:0090160 GO:0008626 GO:0043323 GO:0045954 GO:0050821 GO:1902513 GO:0016032
InterPro	IPR018134 IPR002000
PANTHER	PTHR11506
Pfam	PF01299
PRINTS	PR00336
PROSITE	PS00310 PS00311 PS51407

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0048471	perinuclear region of cytoplasm	PMID:18787122^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P05300	C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P05300	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:20956541^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	PMID:18767904^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:19946888^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1902513	regulation of organelle transport along microtubule	PMID:23632890^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	results_in_movement_of:(GO:0044194)	Seeded From UniProt	complete
involved_in	GO:0090160	Golgi to lysosome transport	PMID:23632890^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:P14222) occurs_in:(GO:0044194)	Seeded From UniProt	complete
involved_in	GO:0072594	establishment of protein localization to organelle	PMID:23632890^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:Q14203) occurs_in:(GO:0044194)	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:19056867^[7]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001088)	Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P11438	P	has_direct_input:(UniProtKB:Q9NP78)	Seeded From UniProt	complete
involved_in	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	PMID:23632890^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043323	positive regulation of natural killer cell degranulation	PMID:23632890^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:22641697^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9NP78	F		Seeded From UniProt	complete
involved_in	GO:0008626	granzyme-mediated apoptotic signaling pathway	PMID:23632890^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	PMID:15792797^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	PMID:15052268^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
colocalizes_with	GO:0005764	lysosome	PMID:15613468^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:15613468^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:15052268^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	PMID:18388320^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	PMID:16542649^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	PMID:15292400^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:23704327^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:22792322^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:16542649^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:15292400^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21266579^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0090160	C		Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0001618	P		Seeded From UniProt	complete
part_of	GO:0061474	phagolysosome membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	P		Seeded From UniProt	complete
part_of	GO:0045335	phagocytic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0044754	autolysosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0044194	cytolytic granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0042470	melanosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0042383	sarcolemma	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0031982	vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0005771	multivesicular body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P11438 ensembl:ENSMUSP00000033824	C		Seeded From UniProt	complete
part_of	GO:0097208	alveolar lamellar body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
involved_in	GO:0048102	autophagic cell death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	P		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
part_of	GO:0030285	integral component of synaptic vesicle membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
part_of	GO:0005773	vacuole	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
part_of	GO:0005771	multivesicular body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14562 ensembl:ENSRNOP00000026580	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002000	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:3174652^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:3174652^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	PMID:3131762^[19]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0101003	ficolin-1-rich granule membrane	Reactome:R-HSA-6800426	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	Reactome:R-HSA-6798695	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0035577	azurophil granule membrane	Reactome:R-HSA-6798739	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-6800426 Reactome:R-HSA-6798739	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0001618	virus receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1183	F		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0458	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0157	C		Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0100	C		Seeded From UniProt	complete
part_of	GO:0005770	late endosome	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0152	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Jackson, LK et al. (2008) The Salmonella virulence protein SifA is a G protein antagonist. Proc. Natl. Acad. Sci. U.S.A. 105 14141-6 PubMed GONUTS page
↑ Perrotta, C et al. (2010) Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function. J. Biol. Chem. 285 40240-51 PubMed GONUTS page
↑ Pons, V et al. (2008) Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol. 6 e214 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Krzewski, K et al. (2013) LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity. Blood 121 4672-83 PubMed GONUTS page
↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
↑ Demirel, Ö et al. (2012) The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2. J. Cell. Sci. 125 4230-40 PubMed GONUTS page
↑ Johnson, DM et al. (2005) Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron. FEBS Lett. 579 1923-9 PubMed GONUTS page
↑ ^10.0 ^10.1 Gissen, P et al. (2004) Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome. Nat. Genet. 36 400-4 PubMed GONUTS page
↑ ^11.0 ^11.1 Bomberger, JM et al. (2005) Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. J. Biol. Chem. 280 9297-307 PubMed GONUTS page
↑ Mukai, A et al. (2008) Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis. J. Cell. Sci. 121 1325-33 PubMed GONUTS page
↑ ^13.0 ^13.1 Ahtiainen, L et al. (2006) Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing. Exp. Cell Res. 312 1540-53 PubMed GONUTS page
↑ ^14.0 ^14.1 Simonsen, A et al. (2004) Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J. Cell. Sci. 117 4239-51 PubMed GONUTS page
↑ Papal, S et al. (2013) The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Hum. Mol. Genet. 22 3773-88 PubMed GONUTS page
↑ Fusco, C et al. (2012) The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. PLoS ONE 7 e40440 PubMed GONUTS page
↑ Watanabe, A et al. (2011) Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J. Biol. Chem. 286 10702-11 PubMed GONUTS page
↑ ^18.0 ^18.1 Howe, CL et al. (1988) Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins. Proc. Natl. Acad. Sci. U.S.A. 85 7577-81 PubMed GONUTS page
↑ Viitala, J et al. (1988) Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000. Proc. Natl. Acad. Sci. U.S.A. 85 3743-7 PubMed GONUTS page

[PMID:18787122-1] Jackson, LK et al. (2008) The Salmonella virulence protein SifA is a G protein antagonist. Proc. Natl. Acad. Sci. U.S.A. 105 14141-6 PubMed GONUTS page

[PMID:20956541-2] Perrotta, C et al. (2010) Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function. J. Biol. Chem. 285 40240-51 PubMed GONUTS page

[PMID:18767904-3] Pons, V et al. (2008) Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol. 6 e214 PubMed GONUTS page

[PMID:23533145-4] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:19946888-5] Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page

[PMID:23632890-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Krzewski, K et al. (2013) LAMP1/CD107a is required for efficient perforin delivery to lytic granules and NK-cell cytotoxicity. Blood 121 4672-83 PubMed GONUTS page

[PMID:19056867-7] Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page

[PMID:22641697-8] Demirel, Ö et al. (2012) The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2. J. Cell. Sci. 125 4230-40 PubMed GONUTS page

[PMID:15792797-9] Johnson, DM et al. (2005) Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron. FEBS Lett. 579 1923-9 PubMed GONUTS page

[PMID:15052268-10] 10.0 ^10.1 Gissen, P et al. (2004) Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome. Nat. Genet. 36 400-4 PubMed GONUTS page

[PMID:15613468-11] 11.0 ^11.1 Bomberger, JM et al. (2005) Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. J. Biol. Chem. 280 9297-307 PubMed GONUTS page

[PMID:18388320-12] Mukai, A et al. (2008) Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis. J. Cell. Sci. 121 1325-33 PubMed GONUTS page

[PMID:16542649-13] 13.0 ^13.1 Ahtiainen, L et al. (2006) Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing. Exp. Cell Res. 312 1540-53 PubMed GONUTS page

[PMID:15292400-14] 14.0 ^14.1 Simonsen, A et al. (2004) Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J. Cell. Sci. 117 4239-51 PubMed GONUTS page

[PMID:23704327-15] Papal, S et al. (2013) The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Hum. Mol. Genet. 22 3773-88 PubMed GONUTS page

[PMID:22792322-16] Fusco, C et al. (2012) The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. PLoS ONE 7 e40440 PubMed GONUTS page

[PMID:21266579-17] Watanabe, A et al. (2011) Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J. Biol. Chem. 286 10702-11 PubMed GONUTS page

[PMID:3174652-18] 18.0 ^18.1 Howe, CL et al. (1988) Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins. Proc. Natl. Acad. Sci. U.S.A. 85 7577-81 PubMed GONUTS page

[PMID:3131762-19] Viitala, J et al. (1988) Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000. Proc. Natl. Acad. Sci. U.S.A. 85 3743-7 PubMed GONUTS page

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HUMAN:LAMP1

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