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YEAST:UAF30
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | UAF30 | |
| Protein Name(s) | Upstream activation factor subunit UAF30
Upstream activation factor 30 KDa subunit p30 | |
| External Links | ||
| UniProt | Q08747 | |
| EMBL | Z75203 BK006948 | |
| PIR | S67199 | |
| RefSeq | NP_014938.3 | |
| ProteinModelPortal | Q08747 | |
| SMR | Q08747 | |
| BioGrid | 34683 | |
| IntAct | Q08747 | |
| MINT | MINT-4503720 | |
| iPTMnet | Q08747 | |
| MaxQB | Q08747 | |
| PRIDE | Q08747 | |
| EnsemblFungi | YOR295W | |
| GeneID | 854470 | |
| KEGG | sce:YOR295W | |
| EuPathDB | FungiDB:YOR295W | |
| SGD | S000005821 | |
| GeneTree | ENSGT00390000006048 | |
| HOGENOM | HOG000000765 | |
| InParanoid | Q08747 | |
| KO | K15223 | |
| OrthoDB | EOG092C4M4L | |
| BioCyc | YEAST:G3O-33780-MONOMER | |
| PRO | PR:Q08747 | |
| Proteomes | UP000002311 | |
| GO | GO:0005730 GO:0000500 GO:0001165 GO:0006325 GO:0006356 GO:0042790 | |
| Gene3D | 1.10.10.60 1.10.245.10 | |
| InterPro | IPR014876 IPR009057 IPR019835 IPR003121 | |
| Pfam | PF08766 PF02201 | |
| SMART | SM00151 | |
| SUPFAM | SSF47592 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005759 |
mitochondrial matrix |
ECO:0000314 |
C |
Figure 6 shows that like human p32, p30 is also localized in the mitochondrial matrix. Upstream activation factor subunit UAF30 Saccharomyces cerevisiae |
complete | |||||
| GO:0016049 |
cell growth |
ECO:0000315 |
P |
Disruption of the p30 gene in yeast caused growth retardation in the glycerol medium, as seen in Figure 7. Thus it can be inferred that p30 is important for cell growth Upstream activation factor subunit UAF30 Saccharomyces cerevisiae |
complete | |||||
|
involved_in |
GO:0042790 |
nucleolar large rRNA transcription by RNA polymerase I |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042790 |
nucleolar large rRNA transcription by RNA polymerase I |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005730 |
nucleolus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001181 |
RNA polymerase I general transcription initiation factor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001165 |
RNA polymerase I upstream control element sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000500 |
RNA polymerase I upstream activating factor complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005730 |
nucleolus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Muta, T et al. (1997) p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation. J. Biol. Chem. 272 24363-70 PubMed GONUTS page
- ↑ 2.0 2.1 Siddiqi, IN et al. (2001) Transcription of chromosomal rRNA genes by both RNA polymerase I and II in yeast uaf30 mutants lacking the 30 kDa subunit of transcription factor UAF. EMBO J. 20 4512-21 PubMed GONUTS page
- ↑ 3.0 3.1 Hontz, RD et al. (2008) Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30. Mol. Cell. Biol. 28 6709-19 PubMed GONUTS page
- ↑ Goetze, H et al. (2010) Alternative chromatin structures of the 35S rRNA genes in Saccharomyces cerevisiae provide a molecular basis for the selective recruitment of RNA polymerases I and II. Mol. Cell. Biol. 30 2028-45 PubMed GONUTS page
- ↑ Ha, CW et al. (2012) Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae. Nucleic Acids Res. 40 4892-903 PubMed GONUTS page
- ↑ Merz, K et al. (2008) Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules. Genes Dev. 22 1190-204 PubMed GONUTS page
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