User:Stoloff1

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
updatedbyinstructor	CAEEL:Q93703	2014-04-03 10:56:04 CDT	GO:0043053 dauer entry (P)	PMID:24385923	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 2, 3.	challenge
unacceptable	VIBCH:PPK	2014-04-03 11:16:00 CDT	GO:0008976 polyphosphate kinase activity (F)	PMID:24511696	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 shows a comparison of the wild type and mutant phenotype when grown in phosphate minimal media. The mutant that had ppk knocked out had a significant lower amount of growth in the minimal media supporting the claim that ppk is necessary for growth in phosphate lacking environments.	challenge
updatedbyinstructor	MOUSE:NF2L2	2014-04-03 12:08:51 CDT	GO:0046326 positive regulation of glucose import (P)	PMID:24024172	ECO:0000314 direct assay evidence used in manual assertion	Figure 1A shows that the activation of the Nrf2 gene results in an increase in the amount of glucose able to be taken in.	challenge
unacceptable	HUMAN:TXTP	2014-04-03 12:31:16 CDT	GO:0006843 mitochondrial citrate transport (P)	PMID:23561848	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2 A and B shows a comparison of urine samples of individuals with a recessive mutation to those without the mutation. The graph shows that individuals with the mutation have a lower amount of citrate and isocitrate.	challenge
acceptable	HUMAN:IDHP	2014-04-03 12:52:06 CDT	GO:0004450 isocitrate dehydrogenase (NADP+) activity (F)	PMID:23226729	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 depicts the activity of isocitrate dehydrogenase. The over expressed IDH2 plasmid is shown to have the highest amount of activity, supporting the claim that IDH2 over expression is correlated with colon cancer.	challenge

acceptable:1
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Stoloff1

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
unacceptable	Min.lorna, Team Ood	BUNYW:NSS	GO:0010629 - negative regulation of gene expression (P)	PMID:11209062	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
updatedbyinstructor	Djgulizia, Team Texas Aggies	YEAST:PIK1	GO:0006897 - endocytosis (P)	PMID:10930462	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Rdesai525, Team Texas Aggies	SCHPO:KLP3	GO:0005881 - cytoplasmic microtubule (C)	PMID:10641037	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1

0 annotations fixed by Stoloff1

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