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User:Hwright

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CACAO Spring 2015

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:AAPK12015-03-24 09:54:44 CDTGO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity (F)PMID:25115398ECO:0000315 mutant phenotype evidence used in manual assertion

PFKFB4 is expressed in multiple normal tissues and over-expressed in human lung adenocarcinomas

challenge
requireschangesHUMAN:FMO32015-03-24 09:57:35 CDTGO:0055114 oxidation-reduction process (P)PMID:20454663ECO:0000314 direct assay evidence used in manual assertion

Figure 2. Alignment of the amino acid sequences of FMOs of various acrtiid species

challenge
unacceptableDANRE:VGFR42015-03-24 10:01:58 CDTGO:0001525 angiogenesis (P)PMID:23393131ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5. Knockdown of ECSCR reduces VEGF-stimulated KDR proteolysis, whereas overexpression of ECSCR results in increased total and surface KDR protein

challenge
correctedthroughchallengesCRIFA:TRYS2015-03-24 10:05:05 CDTGO:0047479 trypanothione synthase activity (F)PMID:24901644ECO:0000314 direct assay evidence used in manual assertion

Figure 3. enzymatic analysis of recombinant purified LdTryS

challenge
unacceptable9HIV1:Q9Q2882015-03-24 10:08:57 CDTGO:0004190 aspartic-type endopeptidase activity (F)PMID:16487302ECO:0000314 direct assay evidence used in manual assertion

Figure 1

challenge

acceptable:0
unacceptable:3
requires_changes:1
flagged:0

Annotations challenged by Hwright

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableJderrickson,
Team Bio Bois
HUMAN:RENIGO:0004195 - obsolete renin activity (F)PMID:25635129ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
requireschangesJderrickson,
Team Bio Bois
ECO27:ATPEGO:0045269 - proton-transporting ATP synthase, central stalk (C)PMID:25603139ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
requireschangesMharrelson,
Team Mic Drop
ECO27:B7UQV9GO:0042710 - biofilm formation (P)PMID:25012525ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2

0 annotations fixed by Hwright

What do the icons mean in the status column?

assessment icons.jpg