User:Courtney.kast4500

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
correctedthroughchallenges	HELAM:I1XB05	2012-10-03 15:38:43 CDT	GO:0016049 cell growth (P)	PMID:23020757	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3b shows the function of AK2 in promoting cell growth and viability	challenge
acceptable	HELAM:I1XB05	2012-10-03 15:38:43 CDT	GO:0035172 hemocyte proliferation (P)	PMID:23020757	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 5 shows that AK2 is necessary for the proliferation of circulating haemocytes.	challenge
unacceptable	MOUSE:1433G	2012-11-04 17:49:32 CST	GO:0005488 binding (F)	PMID:21390248	ECO:0000315 mutant phenotype evidence used in manual assertion	The result showed enhanced binding of 14-3-3γ and η with LRRK2, compared to 14-3-3ζ, ε and θ (Figure 2D)	challenge
updatedbyinstructor	HUMAN:RANB9	2012-11-11 19:15:12 CST	GO:0070373 negative regulation of ERK1 and ERK2 cascade (P)	PMID:23118896	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2 shows RanBPM is a negative regulator of ERK1/2 activation through use of western blots and antibody precitpitation via enhanced phosphorylation	challenge
updatedbyinstructor	ENTFL:Q04114	2012-11-11 19:22:33 CST	GO:0045892 negative regulation of transcription, DNA-dependent (P)	PMID:22544272	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 shows how PrgX has regulatory effects on prgQ transcript	challenge
acceptable	RAT:THY1	2012-11-14 08:38:44 CST	GO:0046777 protein autophosphorylation (P)	PMID:19723805	ECO:0000314 direct assay evidence used in manual assertion	Fig. 2. Thy-1 stimulates FAK autophosphorylation	challenge
updatedbyinstructor	HUMAN:DDX5	2012-11-18 11:31:47 CST	GO:0009299 mRNA transcription (P)	PMID:23143267	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 and 2 show Ddx5 is required for c-fos gene transcriptional activation in response to estradiol. Figure 1: Ddx5 depletion impairs c-fos mRNA production in response to estradiol treatment. Figure 2: Ddx5 depletion impairs c-fos transcriptional induction by estradiol.	challenge
unacceptable	YEAST:MOT1	2012-11-18 11:38:28 CST	GO:2000233 negative regulation of rRNA processing (P)	PMID:17296733	ECO:0000314 direct assay evidence used in manual assertion	Figure 2: Reduced rRNA synthesis and processing in mot1 cells	challenge

acceptable:2
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Courtney.kast4500

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Courtney.kast4500