RAT:THY1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Thy1 (synonyms: Thy-1)
Protein Name(s)	Thy-1 membrane glycoprotein Thy-1 antigen
External Links
UniProt	P01830
EMBL	X03152 X03150 X02002 M18002 M10666
PIR	B45909
RefSeq	NP_036805.1
UniGene	Rn.108198
ProteinModelPortal	P01830
BioGrid	246951
DIP	DIP-1031N
IntAct	P01830
MINT	MINT-4996320
STRING	10116.ENSRNOP00000008685
PhosphoSite	P01830
PaxDb	P01830
PRIDE	P01830
Ensembl	ENSRNOT00000008685
GeneID	24832
KEGG	rno:24832
UCSC	RGD:3860
CTD	7070
RGD	3860
eggNOG	NOG43439
GeneTree	ENSGT00390000012352
HOGENOM	HOG000048719
HOVERGEN	HBG002958
InParanoid	P01830
KO	K06514
OMA	GVPEHSY
OrthoDB	EOG789CCZ
PhylomeDB	P01830
TreeFam	TF336059
NextBio	604560
PRO	PR:P01830
Proteomes	UP000002494
Genevestigator	P01830
GO	GO:0031362 GO:0046658 GO:0016324 GO:0009986 GO:0005829 GO:0030425 GO:0005783 GO:0009897 GO:0070062 GO:0030426 GO:0045121 GO:0005886 GO:0019899 GO:0034235 GO:0019901 GO:0005100 GO:0001525 GO:0007010 GO:0048041 GO:0045576 GO:0043066 GO:0050771 GO:0030336 GO:0048147 GO:0006469 GO:0050860 GO:0043547 GO:0050731 GO:0051281 GO:0032321 GO:0050870 GO:0046549 GO:0016337 GO:0050852
Gene3D	2.60.40.10
InterPro	IPR007110 IPR013783 IPR003599 IPR013151
Pfam	PF00047
SMART	SM00409
PROSITE	PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0046777	protein autophosphorylation	PMID:19723805^[1]	ECO:0000314			P		Fig. 2. Thy-1 stimulates FAK autophosphorylation	complete CACAO 5815
part_of	GO:0045121	membrane raft	PMID:14499952^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002608)	Seeded From UniProt	complete
involved_in	GO:0046777	protein autophosphorylation	PMID:19723805^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity	PMID:18346467^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01831	P		Seeded From UniProt	complete
involved_in	GO:0070571	negative regulation of neuron projection regeneration	PMID:22479590^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	regulates_o_results_in_acquisition_of_features_of:(CL:0002609)	Seeded From UniProt	complete
involved_in	GO:0061099	negative regulation of protein tyrosine kinase activity	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(UniProtKB:Q9WUD9) happens_during:(GO:0010977)	Seeded From UniProt	complete
involved_in	GO:0051894	positive regulation of focal adhesion assembly	PMID:18346467^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04216	P		Seeded From UniProt	complete
involved_in	GO:0043113	receptor clustering	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0032809	neuronal cell body membrane	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0032590	dendrite membrane	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030673	axolemma	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007267	cell-cell signaling	PMID:22479590^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_results_in_acquisition_of_features_of:(CL:0002609)	Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	PMID:18346467^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04216	P		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01831	F		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	PMID:18346467^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04216	F		Seeded From UniProt	complete
involved_in	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	PMID:2873512^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050870	positive regulation of T cell activation	PMID:7722293^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050860	negative regulation of T cell receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01831	P		Seeded From UniProt	complete
involved_in	GO:0050852	T cell receptor signaling pathway	PMID:9285719^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050771	negative regulation of axonogenesis	PMID:15547945^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:12415741^[9]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048147	negative regulation of fibroblast proliferation	PMID:10409250^[10]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048041	focal adhesion assembly	PMID:15093746^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046549	retinal cone cell development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01831	P		Seeded From UniProt	complete
involved_in	GO:0045576	mast cell activation	PMID:8666426^[12]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	PMID:15093746^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0034235	GPI anchor binding	PMID:16257296^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	PMID:10601014^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0030336	negative regulation of cell migration	PMID:15093746^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	PMID:9285719^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01831	C		Seeded From UniProt	complete
involved_in	GO:0007010	cytoskeleton organization	PMID:15093746^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006469	negative regulation of protein kinase activity	PMID:15093746^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:15547945^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:15547945^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005096	GTPase activator activity	PMID:15093746^[11]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P01831	P		Seeded From UniProt	complete
part_of	GO:0046658	anchored component of plasma membrane	PMID:10814697^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	PMID:8870703^[16]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2641	F		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:8666426^[12]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:621017	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:10814697^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
involved_in	GO:0050870	positive regulation of T cell activation	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
involved_in	GO:0050852	T cell receptor signaling pathway	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
involved_in	GO:0050771	negative regulation of axonogenesis	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
involved_in	GO:0048041	focal adhesion assembly	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
involved_in	GO:0046549	retinal cone cell development	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98747 PANTHER:PTN000442448	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98747 PANTHER:PTN000442448 RGD:3860	C		Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
enables	GO:0034235	GPI anchor binding	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	F		Seeded From UniProt	complete
part_of	GO:0031362	anchored component of external side of plasma membrane	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98747 PANTHER:PTN000442448	C		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98747 PANTHER:PTN000442448	C		Seeded From UniProt	complete
involved_in	GO:0030336	negative regulation of cell migration	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	F		Seeded From UniProt	complete
involved_in	GO:0007010	cytoskeleton organization	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
involved_in	GO:0006469	negative regulation of protein kinase activity	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	P		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98747 PANTHER:PTN000442448 UniProtKB:P04216	F		Seeded From UniProt	complete
enables	GO:0005096	GTPase activator activity	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000442448 RGD:3860	F		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	PMID:21873635^[17]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98747 PANTHER:PTN000442448	P		Seeded From UniProt	complete
involved_in	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
involved_in	GO:0070571	negative regulation of neuron projection regeneration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
involved_in	GO:0051894	positive regulation of focal adhesion assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
involved_in	GO:0050860	negative regulation of T cell receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
involved_in	GO:0046549	retinal cone cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	C		Seeded From UniProt	complete
part_of	GO:0031362	anchored component of external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	C		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	C		Seeded From UniProt	complete
involved_in	GO:0007267	cell-cell signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	F		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01831 ensembl:ENSMUSP00000110489	P		Seeded From UniProt	complete
involved_in	GO:0051894	positive regulation of focal adhesion assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	P		Seeded From UniProt	complete
involved_in	GO:0034116	positive regulation of heterotypic cell-cell adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	P		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	C		Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	P		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	C		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	F		Seeded From UniProt	complete
involved_in	GO:0002693	positive regulation of cellular extravasation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	P		Seeded From UniProt	complete
involved_in	GO:0001952	regulation of cell-matrix adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04216 ensembl:ENSP00000284240	P		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033292	F		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033292	P		Seeded From UniProt	complete
involved_in	GO:0030334	regulation of cell migration	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033292	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	PMID:9168818^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:2857477^[19]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0031225	anchored component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0336	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Avalos, AM et al. (2009) Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. J. Cell. Sci. 122 3462-71 PubMed GONUTS page
↑ Ledesma, MD et al. (2003) Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Brain Res. 987 107-16 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Hermosilla, T et al. (2008) Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochim. Biophys. Acta 1783 1111-20 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 ^4.7 Herrera-Molina, R et al. (2012) Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1. PLoS ONE 7 e34295 PubMed GONUTS page
↑ Kroczek, RA et al. () Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature 322 181-4 PubMed GONUTS page
↑ Lancki, DW et al. (1995) Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1. J. Immunol. 154 4363-70 PubMed GONUTS page
↑ ^7.0 ^7.1 Hueber, AO et al. (1997) Thymocytes in Thy-1-/- mice show augmented TCR signaling and impaired differentiation. Curr. Biol. 7 705-8 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Chen, CH et al. (2005) Role of Thy-1 in in vivo and in vitro neural development and regeneration of dorsal root ganglionic neurons. J. Cell. Biochem. 94 684-94 PubMed GONUTS page
↑ Avalos, AM et al. (2002) Signaling triggered by Thy-1 interaction with beta 3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function. Biol. Res. 35 231-8 PubMed GONUTS page
↑ Hagood, JS et al. (1999) Differential expression of platelet-derived growth factor-alpha receptor by Thy-1(-) and Thy-1(+) lung fibroblasts. Am. J. Physiol. 277 L218-24 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Barker, TH et al. (2004) Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity. Exp. Cell Res. 295 488-96 PubMed GONUTS page
↑ ^12.0 ^12.1 Dráberová, L et al. (1996) Thy-1-mediated activation of rat mast cells: the role of Thy-1 membrane microdomains. Immunology 87 141-8 PubMed GONUTS page
↑ Itoh, S et al. (2005) Characterization of a gel-separated unknown glycoprotein by liquid chromatography/multistage tandem mass spectrometry: analysis of rat brain Thy-1 separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J Chromatogr A 1094 105-17 PubMed GONUTS page
↑ Madore, N et al. (1999) Functionally different GPI proteins are organized in different domains on the neuronal surface. EMBO J. 18 6917-26 PubMed GONUTS page
↑ ^15.0 ^15.1 Symons, A et al. (2000) Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1. Glycobiology 10 559-63 PubMed GONUTS page
↑ Narisawa-Saito, M et al. (1996) Thy-1 molecule associates with protein tyrosine kinase(s) in rat mesangial cells. Clin. Exp. Immunol. 106 86-90 PubMed GONUTS page
↑ ^17.00 ^17.01 ^17.02 ^17.03 ^17.04 ^17.05 ^17.06 ^17.07 ^17.08 ^17.09 ^17.10 ^17.11 ^17.12 ^17.13 ^17.14 ^17.15 ^17.16 ^17.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Fujita, N et al. (1997) Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. Exp. Cell Res. 232 400-6 PubMed GONUTS page
↑ Seki, T et al. () Structural organization of the rat thy-1 gene. Nature 313 485-7 PubMed GONUTS page

[PMID:19723805-1] 1.0 ^1.1 Avalos, AM et al. (2009) Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. J. Cell. Sci. 122 3462-71 PubMed GONUTS page

[PMID:14499952-2] Ledesma, MD et al. (2003) Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Brain Res. 987 107-16 PubMed GONUTS page

[PMID:18346467-3] 3.0 ^3.1 ^3.2 ^3.3 Hermosilla, T et al. (2008) Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochim. Biophys. Acta 1783 1111-20 PubMed GONUTS page

[PMID:22479590-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 ^4.7 Herrera-Molina, R et al. (2012) Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1. PLoS ONE 7 e34295 PubMed GONUTS page

[PMID:2873512-5] Kroczek, RA et al. () Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature 322 181-4 PubMed GONUTS page

[PMID:7722293-6] Lancki, DW et al. (1995) Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1. J. Immunol. 154 4363-70 PubMed GONUTS page

[PMID:9285719-7] 7.0 ^7.1 Hueber, AO et al. (1997) Thymocytes in Thy-1-/- mice show augmented TCR signaling and impaired differentiation. Curr. Biol. 7 705-8 PubMed GONUTS page

[PMID:15547945-8] 8.0 ^8.1 ^8.2 Chen, CH et al. (2005) Role of Thy-1 in in vivo and in vitro neural development and regeneration of dorsal root ganglionic neurons. J. Cell. Biochem. 94 684-94 PubMed GONUTS page

[PMID:12415741-9] Avalos, AM et al. (2002) Signaling triggered by Thy-1 interaction with beta 3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function. Biol. Res. 35 231-8 PubMed GONUTS page

[PMID:10409250-10] Hagood, JS et al. (1999) Differential expression of platelet-derived growth factor-alpha receptor by Thy-1(-) and Thy-1(+) lung fibroblasts. Am. J. Physiol. 277 L218-24 PubMed GONUTS page

[PMID:15093746-11] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Barker, TH et al. (2004) Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity. Exp. Cell Res. 295 488-96 PubMed GONUTS page

[PMID:8666426-12] 12.0 ^12.1 Dráberová, L et al. (1996) Thy-1-mediated activation of rat mast cells: the role of Thy-1 membrane microdomains. Immunology 87 141-8 PubMed GONUTS page

[PMID:16257296-13] Itoh, S et al. (2005) Characterization of a gel-separated unknown glycoprotein by liquid chromatography/multistage tandem mass spectrometry: analysis of rat brain Thy-1 separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J Chromatogr A 1094 105-17 PubMed GONUTS page

[PMID:10601014-14] Madore, N et al. (1999) Functionally different GPI proteins are organized in different domains on the neuronal surface. EMBO J. 18 6917-26 PubMed GONUTS page

[PMID:10814697-15] 15.0 ^15.1 Symons, A et al. (2000) Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1. Glycobiology 10 559-63 PubMed GONUTS page

[PMID:8870703-16] Narisawa-Saito, M et al. (1996) Thy-1 molecule associates with protein tyrosine kinase(s) in rat mesangial cells. Clin. Exp. Immunol. 106 86-90 PubMed GONUTS page

[PMID:21873635-17] 17.00 ^17.01 ^17.02 ^17.03 ^17.04 ^17.05 ^17.06 ^17.07 ^17.08 ^17.09 ^17.10 ^17.11 ^17.12 ^17.13 ^17.14 ^17.15 ^17.16 ^17.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9168818-18] Fujita, N et al. (1997) Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. Exp. Cell Res. 232 400-6 PubMed GONUTS page

[PMID:2857477-19] Seki, T et al. () Structural organization of the rat thy-1 gene. Nature 313 485-7 PubMed GONUTS page

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