GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:1433G

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Ywhag
Protein Name(s) 14-3-3 protein gamma

14-3-3 protein gamma, N-terminally processed

External Links
UniProt P61982
EMBL AF058799
CT010208
AK088847
AK148618
AK153307
AK164356
BC008129
CCDS CCDS19748.1
RefSeq NP_061359.2
UniGene Mm.233813
ProteinModelPortal P61982
SMR P61982
BioGrid 204620
IntAct P61982
MINT MINT-1869483
BindingDB P61982
PhosphoSite P61982
REPRODUCTION-2DPAGE P61982
UCD-2DPAGE P61982
MaxQB P61982
PaxDb P61982
PRIDE P61982
Ensembl ENSMUST00000055808
GeneID 22628
KEGG mmu:22628
UCSC uc008zzf.2
CTD 7532
MGI MGI:108109
eggNOG COG5040
GeneTree ENSGT00760000119116
HOVERGEN HBG050423
InParanoid P61982
KO K16198
OMA CQDVLGL
OrthoDB EOG7HHWT3
PhylomeDB P61982
TreeFam TF102003
Reactome REACT_196635
REACT_199054
REACT_243078
REACT_244487
REACT_245720
ChiTaRS Ywhag
NextBio 302991
PRO PR:P61982
Proteomes UP000000589
Bgee P61982
ExpressionAtlas P61982
Genevestigator P61982
GO GO:0030659
GO:0005829
GO:0070062
GO:0003779
GO:0005159
GO:0044822
GO:0019904
GO:0005080
GO:0032869
GO:0006605
GO:0045664
GO:0048167
InterPro IPR000308
IPR023409
IPR023410
PANTHER PTHR18860
Pfam PF00244
PIRSF PIRSF000868
PRINTS PR00305
SMART SM00101
SUPFAM SSF48445
PROSITE PS00796
PS00797

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005488

binding

PMID:21390248[1]

ECO:0000315

F

The result showed enhanced binding of 14-3-3γ and η with LRRK2, compared to 14-3-3ζ, ε and θ (Figure 2D)

complete
CACAO 5654

part_of

GO:0043209

myelin sheath

PMID:17634366[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000128)

Seeded From UniProt

complete

involved_in

GO:0048167

regulation of synaptic plasticity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61981

P

Seeded From UniProt

complete

involved_in

GO:0045664

regulation of neuron differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61981

P

Seeded From UniProt

complete

enables

GO:0005159

insulin-like growth factor receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61981

F

Seeded From UniProt

complete

enables

GO:0005080

protein kinase C binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P61981

F

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P68510

F

Seeded From UniProt

complete

part_of

GO:0098793

presynapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:62002

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048167

regulation of synaptic plasticity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61981

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045664

regulation of neuron differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61981

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:62002

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61981

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032869

cellular response to insulin stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:62002

P

Seeded From UniProt

complete

part_of

GO:0031982

vesicle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:62002

C

Seeded From UniProt

complete

enables

GO:0030971

receptor tyrosine kinase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:62002

F

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

PMID:12446771[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006605

protein targeting

PMID:12446771[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005159

insulin-like growth factor receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61981

F

Seeded From UniProt

complete

enables

GO:0005080

protein kinase C binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P61981

F

Seeded From UniProt

complete

involved_in

GO:0048167

regulation of synaptic plasticity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61981
ensembl:ENSP00000306330

P

Seeded From UniProt

complete

involved_in

GO:0045664

regulation of neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61981
ensembl:ENSP00000306330

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61981
ensembl:ENSP00000306330

F

Seeded From UniProt

complete

enables

GO:0005159

insulin-like growth factor receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61981
ensembl:ENSP00000306330

F

Seeded From UniProt

complete

enables

GO:0005080

protein kinase C binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61981
ensembl:ENSP00000306330

F

Seeded From UniProt

complete

part_of

GO:0098793

presynapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61983
ensembl:ENSRNOP00000069671

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61983
ensembl:ENSRNOP00000069671

C

Seeded From UniProt

complete

involved_in

GO:0032869

cellular response to insulin stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61983
ensembl:ENSRNOP00000069671

P

Seeded From UniProt

complete

part_of

GO:0031982

vesicle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61983
ensembl:ENSRNOP00000069671

C

Seeded From UniProt

complete

enables

GO:0030971

receptor tyrosine kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P61983
ensembl:ENSRNOP00000069671

F

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000308

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-MMU-1454713
Reactome:R-MMU-1445145

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Li, X et al. (2011) Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease. PLoS ONE 6 e17153 PubMed GONUTS page
  2. Werner, HB et al. (2007) Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J. Neurosci. 27 7717-30 PubMed GONUTS page
  3. 3.0 3.1 Eilers, AL et al. (2002) A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex. Mol. Cell. Biol. 22 8514-26 PubMed GONUTS page