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User:Acoppola

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorDROME:Q9NGK52013-03-28 20:16:12 CDTGO:0031594 neuromuscular junction (C)PMID:21228178ECO:0000314 direct assay evidence used in manual assertion

Figure 1: Increased concentration of protein at the NMJs.

challenge
updatedbyinstructorDROME:Q9NGK52013-03-28 20:17:36 CDTGO:0050805 positive regulation of synaptic transmission (P)PMID:21228178ECO:0000315 mutant phenotype evidence used in manual assertion

Inferred from electrophysiology experiments. See figure 3.

challenge
updatedbyinstructorDROME:Q9NGK52013-03-28 20:23:28 CDTGO:0008345 larval locomotory behavior (P)PMID:21228178ECO:0000315 mutant phenotype evidence used in manual assertion

Fig Supplementary 3 (or Fig 9).

challenge
updatedbyinstructorHUMAN:NLGN22013-03-28 20:29:58 CDTGO:0032024 positive regulation of insulin secretion (P)PMID:22528485ECO:0000315 mutant phenotype evidence used in manual assertion

Figure S4: Analysis of insulin granule docking in pancreatic islets from NL-2 knockout mice.

challenge
acceptableHUMAN:NLGN12013-03-28 20:40:36 CDTGO:0031175 neuron projection development (P)PMID:22750515ECO:0000314 direct assay evidence used in manual assertion

"The ability of NLGN1 to induce neurite outgrowth was

evaluated by incubating the neurons with increasing concentrations of recombinant NLGN1." (Page 4177) This was followed by fluorescence staining.

challenge
updatedbyinstructorCAEEL:NLGN12013-03-28 20:54:29 CDTGO:0046929 negative regulation of neurotransmitter secretion (P)PMID:22859820ECO:0000315 mutant phenotype evidence used in manual assertion

See figure 1.

challenge

acceptable:1
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Acoppola

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