MOUSE:TNR5

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Cd40 (synonyms: Tnfrsf5)
Protein Name(s)	Tumor necrosis factor receptor superfamily member 5 B-cell surface antigen CD40 Bp50 CD40L receptor
External Links
UniProt	P27512
EMBL	M83312 M94126 M94129 M94128 M94127 AJ401387 AJ401388 AJ401389 AJ401390 AK089861 AK150959 AK152716 AK152756 AK152942 AK156644 AK161978 AK162305 CT010343 AL591495 AL591411 BC029254
CCDS	CCDS17069.1 CCDS17070.1 CCDS17071.1
PIR	A46476
RefSeq	NP_035741.2 NP_733803.2 NP_733804.1 NP_733805.1 XP_006499216.1
UniGene	Mm.271833
ProteinModelPortal	P27512
SMR	P27512
BioGrid	204251
DIP	DIP-33295N
IntAct	P27512
MINT	MINT-1506277
PhosphoSite	P27512
MaxQB	P27512
PaxDb	P27512
PRIDE	P27512
Ensembl	ENSMUST00000017799 ENSMUST00000073707 ENSMUST00000081310 ENSMUST00000184221
GeneID	21939
KEGG	mmu:21939
UCSC	uc008nwx.1 uc008nwy.1 uc008nwz.1
CTD	958
MGI	MGI:88336
eggNOG	NOG28193
GeneTree	ENSGT00760000119204
HOVERGEN	HBG005117
InParanoid	P27512
KO	K03160
OMA	EKCHPWT
OrthoDB	EOG786H2Q
PhylomeDB	P27512
TreeFam	TF331157
Reactome	REACT_202937
NextBio	301554
PRO	PR:P27512
Proteomes	UP000000589
Bgee	P27512
CleanEx	MM_CD40
ExpressionAtlas	P27512
Genevestigator	P27512
GO	GO:0035631 GO:0009986 GO:0005737 GO:0009897 GO:0005615 GO:0070062 GO:0043231 GO:0005886 GO:0003823 GO:0042113 GO:0006874 GO:0071222 GO:0071260 GO:0051607 GO:0002768 GO:0006954 GO:0030890 GO:0043089 GO:2000353 GO:0043123 GO:0032735 GO:0048304 GO:0043406 GO:0051092 GO:0090037 GO:0032855 GO:0045944 GO:0042511 GO:0043491 GO:0050776 GO:0051023
InterPro	IPR001368 IPR020435
Pfam	PF00020
PRINTS	PR01922
SMART	SM00208
PROSITE	PS00652 PS50050

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005515	protein binding	PMID:20614026^[1]	ECO:0000021		UniProtKB:Q9JIY5	F		Figures 1 & 2 show co-immunoprecipitation using Western blot verification of mass spectrometry results of hmCD40 and hmCD40D67 ARC ‘‘activated receptor capture’’ samples.	complete
	GO:0005515	protein binding	PMID:20614026^[1]	ECO:0000021		UniProtKB:Q924T7	F		Figures 1 & 2 show co-immunoprecipitation using Western blot verification of mass spectrometry results of hmCD40 and hmCD40D67 ARC ‘‘activated receptor capture’’ samples.	complete
	GO:0005515	protein binding	PMID:20614026^[1]	ECO:0000021		UniProtKB:Q9JIQ3	F		Figures 1 & 2 show co-immunoprecipitation using Western blot verification of mass spectrometry results of hmCD40 and hmCD40D67 ARC ‘‘activated receptor capture’’ samples.	complete
	GO:0005886	plasma membrane	PMID:20614026^[1]	ECO:0000314			C		Figure 2. Western blot verification of mass spectrometry results. hmCD40 and hmCD40D67 ARC ‘‘activated receptor capture’’ samples.	complete
part_of	GO:0035631	CD40 receptor complex	PMID:20614026^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006874	cellular calcium ion homeostasis	PMID:21410936^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:20614026^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000353	positive regulation of endothelial cell apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0090037	positive regulation of protein kinase C signaling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051607	defense response to virus	PMID:17277142^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051092	positive regulation of NF-kappaB transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051023	regulation of immunoglobulin secretion	PMID:12958312^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050776	regulation of immune response	PMID:12882831^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048304	positive regulation of isotype switching to IgG isotypes	PMID:12882831^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045766	positive regulation of angiogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043547	positive regulation of GTPase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043491	protein kinase B signaling	PMID:16546095^[6]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000819)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043406	positive regulation of MAP kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	PMID:16708399^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043196	varicosity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042832	defense response to protozoan	PMID:19047410^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042113	B cell activation	PMID:16546095^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042113	B cell activation	PMID:14594818^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032735	positive regulation of interleukin-12 production	PMID:15240714^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030890	positive regulation of B cell proliferation	PMID:15963492^[11]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:87891	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030890	positive regulation of B cell proliferation	PMID:8920854^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030890	positive regulation of B cell proliferation	PMID:8666928^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030890	positive regulation of B cell proliferation	PMID:14607964^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030890	positive regulation of B cell proliferation	PMID:11894097^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030890	positive regulation of B cell proliferation	PMID:10979977^[16]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	F		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:20685650^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:8566034^[18]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000236)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:18684012^[19]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:17277142^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15240714^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:14560001^[20]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000782)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:10979977^[16]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000236)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006954	inflammatory response	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006874	cellular calcium ion homeostasis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	C		Seeded From UniProt	complete
enables	GO:0003823	antigen binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619830	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002768	immune response-regulating cell surface receptor signaling pathway	PMID:15240714^[10]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000782)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25942	P		Seeded From UniProt	complete
involved_in	GO:2000353	positive regulation of endothelial cell apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0090037	positive regulation of protein kinase C signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0071260	cellular response to mechanical stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0051092	positive regulation of NF-kappaB transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0045766	positive regulation of angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0043406	positive regulation of MAP kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	F		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	F		Seeded From UniProt	complete
involved_in	GO:0006874	cellular calcium ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25942 ensembl:ENSP00000361359	P		Seeded From UniProt	complete
involved_in	GO:1901652	response to peptide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0071356	cellular response to tumor necrosis factor	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0071347	cellular response to interleukin-1	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0071222	cellular response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
part_of	GO:0043196	varicosity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	C		Seeded From UniProt	complete
involved_in	GO:0036018	cellular response to erythropoietin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0034341	response to interferon-gamma	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0033590	response to cobalamin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0031667	response to nutrient levels	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	C		Seeded From UniProt	complete
involved_in	GO:0009617	response to bacterium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	C		Seeded From UniProt	complete
enables	GO:0003823	antigen binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4QQW2 ensembl:ENSRNOP00000052022	F		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020435	C		Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020435	F		Seeded From UniProt	complete
involved_in	GO:0042113	B cell activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020435	P		Seeded From UniProt	complete
involved_in	GO:0050776	regulation of immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020435	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0391	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Hostager, BS et al. (2010) HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. PLoS ONE 5 e11380 PubMed GONUTS page
↑ Kim, DY et al. (2011) Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L. J Neuroinflammation 8 25 PubMed GONUTS page
↑ ^3.0 ^3.1 Hervas-Stubbs, S et al. (2007) Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN. J. Immunol. 178 2361-9 PubMed GONUTS page
↑ Hostager, BS et al. (2003) Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling. J. Biol. Chem. 278 45382-90 PubMed GONUTS page
↑ ^5.0 ^5.1 Gerth, AJ et al. (2003) T-bet regulates T-independent IgG2a class switching. Int. Immunol. 15 937-44 PubMed GONUTS page
↑ ^6.0 ^6.1 Aiba, Y et al. (2006) BANK negatively regulates Akt activation and subsequent B cell responses. Immunity 24 259-68 PubMed GONUTS page
↑ Chen, W et al. (2006) Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells. Eur. J. Immunol. 36 1598-607 PubMed GONUTS page
↑ Kamda, JD & Singer, SM (2009) Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia. Infect. Immun. 77 685-93 PubMed GONUTS page
↑ Merluzzi, S et al. (2004) CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism. J. Biol. Chem. 279 1777-86 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 McKee, AS & Pearce, EJ (2004) CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development. J. Immunol. 173 1224-31 PubMed GONUTS page
↑ Skok, M et al. (2005) Nicotinic receptors regulate B lymphocyte activation and immune response. Eur. J. Pharmacol. 517 246-51 PubMed GONUTS page
↑ Chappel, MS et al. (1996) Cross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytes. J. Exp. Med. 184 1639-49 PubMed GONUTS page
↑ Byth, KF et al. (1996) CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation. J. Exp. Med. 183 1707-18 PubMed GONUTS page
↑ Aldrich, MB et al. (2003) Impaired germinal center maturation in adenosine deaminase deficiency. J. Immunol. 171 5562-70 PubMed GONUTS page
↑ Chin, AI et al. (2002) Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 416 190-4 PubMed GONUTS page
↑ ^16.0 ^16.1 Sexl, V et al. (2000) Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. Blood 96 2277-83 PubMed GONUTS page
↑ Takekoshi, T et al. (2010) Identification of a novel marker for dendritic cell maturation, mouse transmembrane protein 123. J. Biol. Chem. 285 31876-84 PubMed GONUTS page
↑ Kong, YY et al. (1995) Differential requirements of CD45 for lymphocyte development and function. Eur. J. Immunol. 25 3431-6 PubMed GONUTS page
↑ Ahn, S et al. (2008) TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. PLoS Biol. 6 e191 PubMed GONUTS page
↑ Pauleau, AL & Murray, PJ (2003) Role of nod2 in the response of macrophages to toll-like receptor agonists. Mol. Cell. Biol. 23 7531-9 PubMed GONUTS page

[PMID:20614026-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Hostager, BS et al. (2010) HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. PLoS ONE 5 e11380 PubMed GONUTS page

[PMID:21410936-2] Kim, DY et al. (2011) Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L. J Neuroinflammation 8 25 PubMed GONUTS page

[PMID:17277142-3] 3.0 ^3.1 Hervas-Stubbs, S et al. (2007) Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN. J. Immunol. 178 2361-9 PubMed GONUTS page

[PMID:12958312-4] Hostager, BS et al. (2003) Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling. J. Biol. Chem. 278 45382-90 PubMed GONUTS page

[PMID:12882831-5] 5.0 ^5.1 Gerth, AJ et al. (2003) T-bet regulates T-independent IgG2a class switching. Int. Immunol. 15 937-44 PubMed GONUTS page

[PMID:16546095-6] 6.0 ^6.1 Aiba, Y et al. (2006) BANK negatively regulates Akt activation and subsequent B cell responses. Immunity 24 259-68 PubMed GONUTS page

[PMID:16708399-7] Chen, W et al. (2006) Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells. Eur. J. Immunol. 36 1598-607 PubMed GONUTS page

[PMID:19047410-8] Kamda, JD & Singer, SM (2009) Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia. Infect. Immun. 77 685-93 PubMed GONUTS page

[PMID:14594818-9] Merluzzi, S et al. (2004) CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism. J. Biol. Chem. 279 1777-86 PubMed GONUTS page

[PMID:15240714-10] 10.0 ^10.1 ^10.2 McKee, AS & Pearce, EJ (2004) CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development. J. Immunol. 173 1224-31 PubMed GONUTS page

[PMID:15963492-11] Skok, M et al. (2005) Nicotinic receptors regulate B lymphocyte activation and immune response. Eur. J. Pharmacol. 517 246-51 PubMed GONUTS page

[PMID:8920854-12] Chappel, MS et al. (1996) Cross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytes. J. Exp. Med. 184 1639-49 PubMed GONUTS page

[PMID:8666928-13] Byth, KF et al. (1996) CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation. J. Exp. Med. 183 1707-18 PubMed GONUTS page

[PMID:14607964-14] Aldrich, MB et al. (2003) Impaired germinal center maturation in adenosine deaminase deficiency. J. Immunol. 171 5562-70 PubMed GONUTS page

[PMID:11894097-15] Chin, AI et al. (2002) Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 416 190-4 PubMed GONUTS page

[PMID:10979977-16] 16.0 ^16.1 Sexl, V et al. (2000) Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. Blood 96 2277-83 PubMed GONUTS page

[PMID:20685650-17] Takekoshi, T et al. (2010) Identification of a novel marker for dendritic cell maturation, mouse transmembrane protein 123. J. Biol. Chem. 285 31876-84 PubMed GONUTS page

[PMID:8566034-18] Kong, YY et al. (1995) Differential requirements of CD45 for lymphocyte development and function. Eur. J. Immunol. 25 3431-6 PubMed GONUTS page

[PMID:18684012-19] Ahn, S et al. (2008) TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. PLoS Biol. 6 e191 PubMed GONUTS page

[PMID:14560001-20] Pauleau, AL & Murray, PJ (2003) Role of nod2 in the response of macrophages to toll-like receptor agonists. Mol. Cell. Biol. 23 7531-9 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

[19]

[20]

MOUSE:TNR5

Contents

Annotations

Notes

References

a

b

c

d

e

g

i

m

n

p

r

s

u

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools