MOUSE:NKX21

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Nkx2-1 (synonyms: Nkx-2.1, Titf1, Ttf1)
Protein Name(s)	Homeobox protein Nkx-2.1 Thyroid nuclear factor 1 Thyroid transcription factor 1 TTF-1 Thyroid-specific enhancer-binding protein T/EBP
External Links
UniProt	P50220
EMBL	U19755 BC080868
CCDS	CCDS25922.1
PIR	S53724
RefSeq	NP_001139670.1 NP_033411.3
UniGene	Mm.89972
ProteinModelPortal	P50220
SMR	P50220
BioGrid	204207
STRING	10090.ENSMUSP00000001536
PhosphoSite	P50220
PaxDb	P50220
PRIDE	P50220
Ensembl	ENSMUST00000001536 ENSMUST00000178477
GeneID	21869
KEGG	mmu:21869
UCSC	uc007npf.3
CTD	7080
MGI	MGI:108067
eggNOG	NOG328614
GeneTree	ENSGT00760000118779
HOGENOM	HOG000231923
HOVERGEN	HBG006689
InParanoid	P50220
KO	K09342
OMA	YGTAMSC
OrthoDB	EOG769ZK0
PhylomeDB	P50220
TreeFam	TF351204
NextBio	301368
PRO	PR:P50220
Proteomes	UP000000589
Bgee	P50220
CleanEx	MM_NKX2-1 MM_TTF1
Genevestigator	P50220
GO	GO:0005654 GO:0005634 GO:0005667 GO:0001047 GO:0003705 GO:0000977 GO:0043565 GO:0003700 GO:0044212 GO:0048646 GO:0007411 GO:0007420 GO:0021795 GO:0021892 GO:0021895 GO:0060486 GO:0031128 GO:0007492 GO:0060441 GO:0021798 GO:0021879 GO:0021877 GO:0021759 GO:0021766 GO:0033327 GO:0007626 GO:0030324 GO:0060430 GO:0030336 GO:0010719 GO:0000122 GO:0045892 GO:0030512 GO:0048663 GO:0001764 GO:0048709 GO:0009887 GO:0007389 GO:0006644 GO:0021983 GO:0042753 GO:0045944 GO:0045893 GO:0006357 GO:0006355 GO:0009725 GO:0048511 GO:0022029 GO:0021537 GO:0030878 GO:0006366 GO:0060510
Gene3D	1.10.10.60
InterPro	IPR017970 IPR001356 IPR020479 IPR009057
Pfam	PF00046
PRINTS	PR00024
SMART	SM00389
SUPFAM	SSF46689
PROSITE	PS00027 PS50071

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	PMID:22356123^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:22955271^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	PMID:22955271^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:22955271^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:22356123^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:15356023^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:22356123^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042753	positive regulation of circadian rhythm	PMID:22356123^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P23441	C		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:22356123^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004110 FB:FBgn0004862 FB:FBgn0040318 FB:FBgn0261930 MGI:MGI:108067 MGI:MGI:97347 MGI:MGI:97348 MGI:MGI:97350 PANTHER:PTN000678271 RGD:3866 UniProtKB:A6NCS4 UniProtKB:A6NJ46 UniProtKB:O15522 UniProtKB:P43699 UniProtKB:P52952 UniProtKB:Q99801 WB:WBGene00000445 WB:WBGene00000450	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000576 FB:FBgn0004110 FB:FBgn0004862 MGI:MGI:108015 MGI:MGI:108067 MGI:MGI:1352738 MGI:MGI:97347 MGI:MGI:97350 MGI:MGI:97352 PANTHER:PTN000678271 RGD:1310629 RGD:3866 RGD:620520 RGD:69318 UniProtKB:A6NCS4 UniProtKB:A6NJ46 UniProtKB:O15522 UniProtKB:P43699 UniProtKB:P52952 UniProtKB:Q99801 WB:WBGene00000445	F		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000576 FB:FBgn0002941 FB:FBgn0004110 FB:FBgn0028993 FB:FBgn0040318 FB:FBgn0261930 MGI:MGI:108015 MGI:MGI:108067 MGI:MGI:1206039 MGI:MGI:1270158 MGI:MGI:1352738 MGI:MGI:1921811 MGI:MGI:97347 MGI:MGI:97348 MGI:MGI:97350 MGI:MGI:97351 PANTHER:PTN000678271 RGD:620520 RGD:69318 UniProtKB:P52952 WB:WBGene00000445 WB:WBGene00000584 ZFIN:ZDB-GENE-030328-42 ZFIN:ZDB-GENE-040718-178 ZFIN:ZDB-GENE-050217-3 ZFIN:ZDB-GENE-070626-1 ZFIN:ZDB-GENE-980526-321 ZFIN:ZDB-GENE-980526-403 ZFIN:ZDB-GENE-990415-179	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000576 FB:FBgn0002941 FB:FBgn0004110 FB:FBgn0004862 FB:FBgn0040318 FB:FBgn0261930 MGI:MGI:108067 MGI:MGI:1206039 MGI:MGI:1352738 MGI:MGI:97347 MGI:MGI:97350 MGI:MGI:97352 PANTHER:PTN000678271 RGD:1308443 RGD:1310629 RGD:3866 RGD:620520 RGD:69318 UniProtKB:F1NC42 UniProtKB:P43699 UniProtKB:P52952 UniProtKB:Q90788 UniProtKB:Q99801 WB:WBGene00000445	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0261930 MGI:MGI:108067 MGI:MGI:1352738 MGI:MGI:97347 MGI:MGI:97350 MGI:MGI:97352 PANTHER:PTN000678271 RGD:3866 RGD:69318 UniProtKB:A6NCS4 UniProtKB:O15522 UniProtKB:P43699 UniProtKB:P52952 UniProtKB:Q99801	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108015 MGI:MGI:108067 MGI:MGI:1352738 MGI:MGI:97350 PANTHER:PTN000678271 RGD:69318 UniProtKB:O15522 UniProtKB:P52952 UniProtKB:Q99801	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060510	type II pneumocyte differentiation	PMID:17164424^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107516	P	occurs_in:(EMAPA:16728) results_in_acquisition_of_features_of:(CL:0000322)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060486	Clara cell differentiation	PMID:17164424^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107516	P	occurs_in:(EMAPA:16728) results_in_acquisition_of_features_of:(CL:0000158)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060430	lung saccule development	PMID:17164424^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107516	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048709	oligodendrocyte differentiation	PMID:11493571^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:98297	P	occurs_in:(EMAPA:16910) results_in_acquisition_of_features_of:(CL:0000128)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048709	oligodendrocyte differentiation	PMID:11171336^[7]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:98297	P	occurs_in:(EMAPA:16910) results_in_acquisition_of_features_of:(CL:0000128)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048663	neuron fate commitment	PMID:20181579^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048663	neuron fate commitment	PMID:18786356^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P	has_participant:(EMAPA:16910) results_in_commitment_to:(CL:0000099)\|has_participant(EMAPA:16910) results_in_commitment_to:(CL:0000099)\|has_participant(EMAPA:17544) results_in_commitment_to:(CL:0000099)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048646	anatomical structure formation involved in morphogenesis	PMID:17522155^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	results_in_formation_of:(EMAPA:16853)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17409236^[11]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107516	P	has_regulation_target:(MGI:MGI:1916782)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17347682^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1353422	P	has_regulation_target:(MGI:MGI:109518)\|has_regulation_target:(MGI:MGI:1347474)\|has_regulation_target:(MGI:MGI:98919)\|has_regulation_target:(MGI:MGI:107543)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17164424^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107516	P	has_regulation_target:(MGI:MGI:98239)\|has_regulation_target:(MGI:MGI:94919)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:16998587^[13]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:103296	P	has_regulation_target:(MGI:MGI:109518)\|has_regulation_target:(MGI:MGI:109516)\|has_regulation_target:(MGI:MGI:109517)\|has_regulation_target:(MGI:MGI:1351617)\|has_regulation_target:(MGI:MGI:107172)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:16510470^[14]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:106658 MGI:MGI:107516	P	has_regulation_target:(MGI:MGI:109518)\|has_regulation_target:(MGI:MGI:109516)\|has_regulation_target:(MGI:MGI:109517)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:7896788^[15]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:109518)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:20160132^[16]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:98733)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:18632661^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:18339674^[18]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:1306803)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:18033672^[19]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:101784)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17409236^[11]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:1916782)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:16033766^[20]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:14970209^[21]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:109517)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:11914369^[22]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:9214635^[23]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P23441	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P23441	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	PMID:14970209^[21]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1917649	P	has_regulation_target:(MGI:MGI:109517)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
enables	GO:0044213	intronic transcription regulatory region DNA binding	PMID:23143308^[24]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:18632661^[17]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:7896788^[15]	ECO:0000314	direct assay evidence used in manual assertion		F	has_input:(MGI:MGI:109518)	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:11914369^[22]	ECO:0000314	direct assay evidence used in manual assertion		F	has_input:(MGI:MGI:98962)	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	F		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042538	hyperosmotic salinity response	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0033327	Leydig cell differentiation	PMID:12399445^[25]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	occurs_in:(EMAPA:19175) results_in_acquisition_of_features_of:(CL:0000178)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032496	response to lipopolysaccharide	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031128	developmental induction	PMID:9806931^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	has_participant:(EMAPA:16899)\|has_participant:(EMAPA:16725)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030878	thyroid gland development	PMID:16150900^[27]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:97492	P	results_in_development_of:(EMAPA:17068)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030878	thyroid gland development	PMID:16601074^[28]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653644,MGI:MGI:3653645	P	results_in_development_of:(EMAPA:36504)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030878	thyroid gland development	PMID:15581879^[29]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030878	thyroid gland development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030878	thyroid gland development	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030336	negative regulation of cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030324	lung development	PMID:21350014^[30]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:3619325 MGI:MGI:3619326 MGI:MGI:3619327 MGI:MGI:3619328 MGI:MGI:3619373	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030324	lung development	PMID:12829717^[31]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677488	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030324	lung development	PMID:10706142^[32]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030324	lung development	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0022029	telencephalon cell migration	PMID:20181579^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P	occurs_in:(EMAPA:16910)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0022029	telencephalon cell migration	PMID:18786357^[33]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P	occurs_in:(EMAPA:17549) results_in_movement_of:(CL:0000099)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021983	pituitary gland development	PMID:9806931^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	results_in_development_of:(EMAPA:16899)\|results_in_development_of:(EMAPA:16725)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021895	cerebral cortex neuron differentiation	PMID:18339674^[18]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1306803	P	occurs_in:(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000498)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021895	cerebral cortex neuron differentiation	PMID:18339674^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	occurs_in:(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000498)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021892	cerebral cortex GABAergic interneuron differentiation	PMID:18786356^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P	occurs_in:(EMAPA:16910) results_in_acquisition_of_features_of:(CL:0000617)\|occurs_in(EMAPA:16910) results_in_acquisition_of_features_of:(CL:0000099)\|occurs_in(EMAPA:16910) results_in_acquisition_of_features_of:(CL:0000617)\|occurs_in(EMAPA:16910) results_in_acquisition_of_features_of:(CL:0000099)\|occurs_in(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000617)\|occurs_in(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000099)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021892	cerebral cortex GABAergic interneuron differentiation	PMID:15028753^[34]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	occurs_in:(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000172)\|occurs_in(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000099)\|occurs_in(EMAPA:17544) results_in_acquisition_of_features_of:(CL:0000617)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021879	forebrain neuron differentiation	PMID:11163262^[35]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	occurs_in:(EMAPA:32845) results_in_acquisition_of_features_of:(CL:0000617)\|occurs_in(EMAPA:32845) results_in_acquisition_of_features_of:(CL:0000172)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021877	forebrain neuron fate commitment	PMID:18339674^[18]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1306803	P	occurs_in:(EMAPA:17544) results_in_commitment_to:(CL:0000498)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021877	forebrain neuron fate commitment	PMID:18339674^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	occurs_in:(EMAPA:17544) results_in_commitment_to:(CL:0000498)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021798	forebrain dorsal/ventral pattern formation	PMID:11830575^[36]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	has_participant:(EMAPA:16910)\|has_participant:(EMAPA:17536)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021798	forebrain dorsal/ventral pattern formation	PMID:11163262^[35]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021798	forebrain dorsal/ventral pattern formation	PMID:10393115^[37]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	has_participant:(EMAPA:16910)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021795	cerebral cortex cell migration	PMID:18786357^[33]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(EMAPA:17544) results_in_movement_of:(CL:0000099)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021766	hippocampus development	PMID:11163262^[35]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021759	globus pallidus development	PMID:20181579^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P	results_in_development_of:(EMAPA:35380)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021759	globus pallidus development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021537	telencephalon development	PMID:18786356^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3653645	P	results_in_development_of:(EMAPA:16910)\|results_in_development_of:(EMAPA:16910)\|results_in_development_of:(EMAPA:16910)\|results_in_development_of:(EMAPA:16910)	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0017025	TBP-class protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010719	negative regulation of epithelial to mesenchymal transition	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009887	animal organ morphogenesis	PMID:8557195^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007631	feeding behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007626	locomotory behavior	PMID:11854318^[39]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007626	locomotory behavior	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007492	endoderm development	PMID:8557195^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007492	endoderm development	PMID:10208743^[40]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007420	brain development	PMID:12930780^[41]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95843	P	results_in_development_of:(EMAPA:16910)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007420	brain development	PMID:8557195^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007420	brain development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007411	axon guidance	PMID:11830575^[36]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007389	pattern specification process	PMID:12930780^[41]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95843	P	occurs_in:(EMAPA:16910)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006644	phospholipid metabolic process	PMID:17164424^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107516	P	occurs_in:(EMAPA:16728) occurs_in:(CL:0000322)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006357	regulation of transcription by RNA polymerase II	PMID:18632661^[17]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006355	regulation of transcription, DNA-templated	PMID:11733512^[42]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:17164424^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:14970209^[21]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:11733512^[42]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:8813084^[43]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16896)\|part_of:(EMAPA:16724)\|part_of:(EMAPA:16898)\|part_of:(EMAPA:17068)\|part_of:(EMAPA:16731) part_of:(CL:0000066)\|part_of:(EMAPA:16735) part_of:(CL:0000066)\|part_of:(EMAPA:16851) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:17655) part_of:(CL:0000066)\|part_of:(EMAPA:17663) part_of:(CL:0000066)\|part_of:(EMAPA:35121) part_of:(CL:0000066)\|part_of:(EMAPA:32693) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:7896788^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21402781^[44]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:20181579^[8]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35380)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19010321^[45]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:17068)\|part_of:(EMAPA:17068)\|part_of:(EMAPA:36504)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17522155^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:18862) part_of:(CL:0000075)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17079460^[46]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16731) part_of:(CL:0000066)\|part_of:(EMAPA:16735) part_of:(CL:0000066)\|part_of:(EMAPA:16855) part_of:(CL:0000066)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16998587^[13]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35121) part_of:(CL:0000082)\|part_of:(EMAPA:32693) part_of:(CL:0000082)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16601074^[28]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:36504)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:15576401^[47]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16250) part_of:(CL:0000223)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:12829717^[31]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11724907^[48]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16731)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P23441	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:18786357^[33]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:17164424^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:11914369^[22]	ECO:0000314	direct assay evidence used in manual assertion		F	has_regulation_target:(MGI:MGI:98962)	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:11733512^[42]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P23441	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O14956	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002016	regulation of blood volume by renin-angiotensin	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001764	neuron migration	PMID:12902388^[49]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857494	P	occurs_in:(EMAPA:17544) results_in_movement_of:(CL:0000117)	Seeded From UniProt	complete
enables	GO:0001047	core promoter binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
enables	GO:0001012	RNA polymerase II regulatory region DNA binding	PMID:23143308^[24]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:7896788^[15]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:18033672^[19]	ECO:0000314	direct assay evidence used in manual assertion		F	has_regulation_target:(MGI:MGI:101784)	Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	PMID:21402781^[44]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	PMID:23143308^[24]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3866	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:18786357^[33]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:1100492)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:23143308^[24]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43699	P		Seeded From UniProt	complete
involved_in	GO:0060441	epithelial tube branching involved in lung morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
enables	GO:0044213	intronic transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
involved_in	GO:0030900	forebrain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0030878	thyroid gland development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0030336	negative regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0030324	lung development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0021759	globus pallidus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
involved_in	GO:0010719	negative regulation of epithelial to mesenchymal transition	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0009725	response to hormone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
enables	GO:0001012	RNA polymerase II regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43699 ensembl:ENSP00000346879	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001356 InterPro:IPR009057 InterPro:IPR020479	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017970	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0371 UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Matagne, V et al. (2012) Thyroid transcription factor 1, a homeodomain containing transcription factor, contributes to regulating periodic oscillations in GnRH gene expression. J. Neuroendocrinol. 24 916-29 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Varma, S et al. (2012) The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J. Biol. Chem. 287 37282-95 PubMed GONUTS page
↑ Meeus, L et al. (2004) Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid. J. Clin. Endocrinol. Metab. 89 4285-91 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 Zhang, Y et al. (2007) GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development 134 189-98 PubMed GONUTS page
↑ Tekki-Kessaris, N et al. (2001) Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development 128 2545-54 PubMed GONUTS page
↑ Nery, S et al. (2001) Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain. Development 128 527-40 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 Flandin, P et al. (2010) The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. J. Neurosci. 30 2812-23 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Butt, SJ et al. (2008) The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron 59 722-32 PubMed GONUTS page
↑ ^10.0 ^10.1 Que, J et al. (2007) Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development 134 2521-31 PubMed GONUTS page
↑ ^11.0 ^11.1 Cheng, A et al. (2007) Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage. J. Neurosci. 27 3722-33 PubMed GONUTS page
↑ Park, KS et al. (2007) SPDEF regulates goblet cell hyperplasia in the airway epithelium. J. Clin. Invest. 117 978-88 PubMed GONUTS page
↑ ^13.0 ^13.1 Davé, V et al. (2006) Calcineurin/Nfat signaling is required for perinatal lung maturation and function. J. Clin. Invest. 116 2597-609 PubMed GONUTS page
↑ Yin, Z et al. (2006) Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression. Am. J. Physiol. Lung Cell Mol. Physiol. 291 L191-9 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 ^15.3 Bruno, MD et al. (1995) Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1. J. Biol. Chem. 270 6531-6 PubMed GONUTS page
↑ Amendola, E et al. (2010) A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid. Endocrinology 151 1948-58 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 Tomita, T et al. (2008) CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. J. Biol. Chem. 283 25617-27 PubMed GONUTS page
↑ ^18.0 ^18.1 ^18.2 ^18.3 ^18.4 Du, T et al. (2008) NKX2.1 specifies cortical interneuron fate by activating Lhx6. Development 135 1559-67 PubMed GONUTS page
↑ ^19.0 ^19.1 Pelizzoli, R et al. (2008) TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin. Int. J. Dev. Biol. 52 55-62 PubMed GONUTS page
↑ Reynolds, PR & Hoidal, JR (2005) Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development. J. Biol. Chem. 280 32548-54 PubMed GONUTS page
↑ ^21.0 ^21.1 ^21.2 Park, KS et al. (2004) TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J. Biol. Chem. 279 17384-90 PubMed GONUTS page
↑ ^22.0 ^22.1 ^22.2 Weidenfeld, J et al. (2002) The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J. Biol. Chem. 277 21061-70 PubMed GONUTS page
↑ Zannini, M et al. (1997) TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J. 16 3185-97 PubMed GONUTS page
↑ ^24.0 ^24.1 ^24.2 ^24.3 Maeda, Y et al. (2012) Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung. J. Clin. Invest. 122 4388-400 PubMed GONUTS page
↑ Pakarinen, P et al. (2002) Pituitary hormones are not required for sexual differentiation of male mice: phenotype of the T/ebp/Nkx2.1 null mutant mice. Endocrinology 143 4477-82 PubMed GONUTS page
↑ ^26.0 ^26.1 Takuma, N et al. (1998) Formation of Rathke's pouch requires dual induction from the diencephalon. Development 125 4835-40 PubMed GONUTS page
↑ Amendola, E et al. (2005) A mouse model demonstrates a multigenic origin of congenital hypothyroidism. Endocrinology 146 5038-47 PubMed GONUTS page
↑ ^28.0 ^28.1 Kusakabe, T et al. (2006) Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid. Mol. Endocrinol. 20 1796-809 PubMed GONUTS page
↑ Parlato, R et al. (2004) An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev. Biol. 276 464-75 PubMed GONUTS page
↑ Tian, Y et al. (2011) Regulation of lung endoderm progenitor cell behavior by miR302/367. Development 138 1235-45 PubMed GONUTS page
↑ ^31.0 ^31.1 DeFelice, M et al. (2003) TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression. J. Biol. Chem. 278 35574-83 PubMed GONUTS page
↑ Yuan, B et al. (2000) Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev. Dyn. 217 180-90 PubMed GONUTS page
↑ ^33.0 ^33.1 ^33.2 ^33.3 Nóbrega-Pereira, S et al. (2008) Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors. Neuron 59 733-45 PubMed GONUTS page
↑ Xu, Q et al. (2004) Origins of cortical interneuron subtypes. J. Neurosci. 24 2612-22 PubMed GONUTS page
↑ ^35.0 ^35.1 ^35.2 Pleasure, SJ et al. (2000) Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron 28 727-40 PubMed GONUTS page
↑ ^36.0 ^36.1 Marín, O et al. (2002) Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections. Development 129 761-73 PubMed GONUTS page
↑ Sussel, L et al. (1999) Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development 126 3359-70 PubMed GONUTS page
↑ ^38.0 ^38.1 ^38.2 Kimura, S et al. (1996) The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10 60-9 PubMed GONUTS page
↑ Pohlenz, J et al. (2002) Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. J. Clin. Invest. 109 469-73 PubMed GONUTS page
↑ Minoo, P et al. (1999) Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev. Biol. 209 60-71 PubMed GONUTS page
↑ ^41.0 ^41.1 Corbin, JG et al. (2003) Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development 130 4895-906 PubMed GONUTS page
↑ ^42.0 ^42.1 ^42.2 Liu, C et al. (2002) GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. J. Biol. Chem. 277 4519-25 PubMed GONUTS page
↑ Zhou, L et al. (1996) Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J. Histochem. Cytochem. 44 1183-93 PubMed GONUTS page
↑ ^44.0 ^44.1 Benlhabib, H & Mendelson, CR (2011) Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol. Cell. Biol. 31 1949-58 PubMed GONUTS page
↑ Di Palma, T et al. (2009) TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation. Exp. Cell Res. 315 162-75 PubMed GONUTS page
↑ Tian, J et al. (2006) Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia. Cancer Res. 66 10399-407 PubMed GONUTS page
↑ Serls, AE et al. (2005) Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 132 35-47 PubMed GONUTS page
↑ Miller, LA et al. (2001) Immunolocalization of sonic hedgehog (Shh) in developing mouse lung. J. Histochem. Cytochem. 49 1593-604 PubMed GONUTS page
↑ Nery, S et al. (2003) Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb. Cortex 13 895-903 PubMed GONUTS page

[PMID:22356123-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Matagne, V et al. (2012) Thyroid transcription factor 1, a homeodomain containing transcription factor, contributes to regulating periodic oscillations in GnRH gene expression. J. Neuroendocrinol. 24 916-29 PubMed GONUTS page

[PMID:22955271-2] 2.0 ^2.1 ^2.2 Varma, S et al. (2012) The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J. Biol. Chem. 287 37282-95 PubMed GONUTS page

[PMID:15356023-3] Meeus, L et al. (2004) Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid. J. Clin. Endocrinol. Metab. 89 4285-91 PubMed GONUTS page

[PMID:21873635-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:17164424-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 Zhang, Y et al. (2007) GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development 134 189-98 PubMed GONUTS page

[PMID:11493571-6] Tekki-Kessaris, N et al. (2001) Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development 128 2545-54 PubMed GONUTS page

[PMID:11171336-7] Nery, S et al. (2001) Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain. Development 128 527-40 PubMed GONUTS page

[PMID:20181579-8] 8.0 ^8.1 ^8.2 ^8.3 Flandin, P et al. (2010) The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. J. Neurosci. 30 2812-23 PubMed GONUTS page

[PMID:18786356-9] 9.0 ^9.1 ^9.2 Butt, SJ et al. (2008) The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron 59 722-32 PubMed GONUTS page

[PMID:17522155-10] 10.0 ^10.1 Que, J et al. (2007) Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development 134 2521-31 PubMed GONUTS page

[PMID:17409236-11] 11.0 ^11.1 Cheng, A et al. (2007) Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage. J. Neurosci. 27 3722-33 PubMed GONUTS page

[PMID:17347682-12] Park, KS et al. (2007) SPDEF regulates goblet cell hyperplasia in the airway epithelium. J. Clin. Invest. 117 978-88 PubMed GONUTS page

[PMID:16998587-13] 13.0 ^13.1 Davé, V et al. (2006) Calcineurin/Nfat signaling is required for perinatal lung maturation and function. J. Clin. Invest. 116 2597-609 PubMed GONUTS page

[PMID:16510470-14] Yin, Z et al. (2006) Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression. Am. J. Physiol. Lung Cell Mol. Physiol. 291 L191-9 PubMed GONUTS page

[PMID:7896788-15] 15.0 ^15.1 ^15.2 ^15.3 Bruno, MD et al. (1995) Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1. J. Biol. Chem. 270 6531-6 PubMed GONUTS page

[PMID:20160132-16] Amendola, E et al. (2010) A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid. Endocrinology 151 1948-58 PubMed GONUTS page

[PMID:18632661-17] 17.0 ^17.1 ^17.2 Tomita, T et al. (2008) CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. J. Biol. Chem. 283 25617-27 PubMed GONUTS page

[PMID:18339674-18] 18.0 ^18.1 ^18.2 ^18.3 ^18.4 Du, T et al. (2008) NKX2.1 specifies cortical interneuron fate by activating Lhx6. Development 135 1559-67 PubMed GONUTS page

[PMID:18033672-19] 19.0 ^19.1 Pelizzoli, R et al. (2008) TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin. Int. J. Dev. Biol. 52 55-62 PubMed GONUTS page

[PMID:16033766-20] Reynolds, PR & Hoidal, JR (2005) Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development. J. Biol. Chem. 280 32548-54 PubMed GONUTS page

[PMID:14970209-21] 21.0 ^21.1 ^21.2 Park, KS et al. (2004) TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J. Biol. Chem. 279 17384-90 PubMed GONUTS page

[PMID:11914369-22] 22.0 ^22.1 ^22.2 Weidenfeld, J et al. (2002) The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J. Biol. Chem. 277 21061-70 PubMed GONUTS page

[PMID:9214635-23] Zannini, M et al. (1997) TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J. 16 3185-97 PubMed GONUTS page

[PMID:23143308-24] 24.0 ^24.1 ^24.2 ^24.3 Maeda, Y et al. (2012) Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung. J. Clin. Invest. 122 4388-400 PubMed GONUTS page

[PMID:12399445-25] Pakarinen, P et al. (2002) Pituitary hormones are not required for sexual differentiation of male mice: phenotype of the T/ebp/Nkx2.1 null mutant mice. Endocrinology 143 4477-82 PubMed GONUTS page

[PMID:9806931-26] 26.0 ^26.1 Takuma, N et al. (1998) Formation of Rathke's pouch requires dual induction from the diencephalon. Development 125 4835-40 PubMed GONUTS page

[PMID:16150900-27] Amendola, E et al. (2005) A mouse model demonstrates a multigenic origin of congenital hypothyroidism. Endocrinology 146 5038-47 PubMed GONUTS page

[PMID:16601074-28] 28.0 ^28.1 Kusakabe, T et al. (2006) Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid. Mol. Endocrinol. 20 1796-809 PubMed GONUTS page

[PMID:15581879-29] Parlato, R et al. (2004) An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev. Biol. 276 464-75 PubMed GONUTS page

[PMID:21350014-30] Tian, Y et al. (2011) Regulation of lung endoderm progenitor cell behavior by miR302/367. Development 138 1235-45 PubMed GONUTS page

[PMID:12829717-31] 31.0 ^31.1 DeFelice, M et al. (2003) TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression. J. Biol. Chem. 278 35574-83 PubMed GONUTS page

[PMID:10706142-32] Yuan, B et al. (2000) Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev. Dyn. 217 180-90 PubMed GONUTS page

[PMID:18786357-33] 33.0 ^33.1 ^33.2 ^33.3 Nóbrega-Pereira, S et al. (2008) Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors. Neuron 59 733-45 PubMed GONUTS page

[PMID:15028753-34] Xu, Q et al. (2004) Origins of cortical interneuron subtypes. J. Neurosci. 24 2612-22 PubMed GONUTS page

[PMID:11163262-35] 35.0 ^35.1 ^35.2 Pleasure, SJ et al. (2000) Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron 28 727-40 PubMed GONUTS page

[PMID:11830575-36] 36.0 ^36.1 Marín, O et al. (2002) Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections. Development 129 761-73 PubMed GONUTS page

[PMID:10393115-37] Sussel, L et al. (1999) Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development 126 3359-70 PubMed GONUTS page

[PMID:8557195-38] 38.0 ^38.1 ^38.2 Kimura, S et al. (1996) The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10 60-9 PubMed GONUTS page

[PMID:11854318-39] Pohlenz, J et al. (2002) Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. J. Clin. Invest. 109 469-73 PubMed GONUTS page

[PMID:10208743-40] Minoo, P et al. (1999) Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev. Biol. 209 60-71 PubMed GONUTS page

[PMID:12930780-41] 41.0 ^41.1 Corbin, JG et al. (2003) Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development 130 4895-906 PubMed GONUTS page

[PMID:11733512-42] 42.0 ^42.1 ^42.2 Liu, C et al. (2002) GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. J. Biol. Chem. 277 4519-25 PubMed GONUTS page

[PMID:8813084-43] Zhou, L et al. (1996) Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J. Histochem. Cytochem. 44 1183-93 PubMed GONUTS page

[PMID:21402781-44] 44.0 ^44.1 Benlhabib, H & Mendelson, CR (2011) Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol. Cell. Biol. 31 1949-58 PubMed GONUTS page

[PMID:19010321-45] Di Palma, T et al. (2009) TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation. Exp. Cell Res. 315 162-75 PubMed GONUTS page

[PMID:17079460-46] Tian, J et al. (2006) Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia. Cancer Res. 66 10399-407 PubMed GONUTS page

[PMID:15576401-47] Serls, AE et al. (2005) Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 132 35-47 PubMed GONUTS page

[PMID:11724907-48] Miller, LA et al. (2001) Immunolocalization of sonic hedgehog (Shh) in developing mouse lung. J. Histochem. Cytochem. 49 1593-604 PubMed GONUTS page

[PMID:12902388-49] Nery, S et al. (2003) Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb. Cortex 13 895-903 PubMed GONUTS page

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