MOUSE:FOS

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Fos
Protein Name(s)	Proto-oncogene c-Fos Cellular oncogene fos
External Links
UniProt	P01101
EMBL	V00727 J00370 BC029814
CCDS	CCDS26059.1
PIR	A01343
RefSeq	NP_034364.1
UniGene	Mm.246513
PDB	2WT7
PDBsum	2WT7
ProteinModelPortal	P01101
SMR	P01101
BioGrid	199726
DIP	DIP-1066N
IntAct	P01101
MINT	MINT-1500015
STRING	10090.ENSMUSP00000021674
PhosphoSite	P01101
PRIDE	P01101
Ensembl	ENSMUST00000021674
GeneID	14281
KEGG	mmu:14281
UCSC	uc007oha.2
CTD	2353
MGI	MGI:95574
eggNOG	NOG258795
GeneTree	ENSGT00730000110541
HOGENOM	HOG000234334
HOVERGEN	HBG005743
InParanoid	P01101
KO	K04379
OMA	DWEPLYT
OrthoDB	EOG7VTDN9
PhylomeDB	P01101
TreeFam	TF326301
Reactome	R-MMU-2559580 R-MMU-2871796 R-MMU-450341
ChiTaRS	Fos
NextBio	285657
PRO	PR:P01101
Proteomes	UP000000589
Bgee	P01101
CleanEx	MM_FOS
Genevisible	P01101
GO	GO:0005829 GO:0005783 GO:0016020 GO:0043005 GO:0005654 GO:0005634 GO:0005667 GO:0003682 GO:0003677 GO:0003690 GO:0070412 GO:0000978 GO:0001077 GO:0000979 GO:0003700 GO:0008134 GO:0044212 GO:0007568 GO:0071277 GO:0031668 GO:0032870 GO:0034614 GO:0001661 GO:0007565 GO:0007399 GO:0045672 GO:0045944 GO:0045893 GO:0006355 GO:0051591 GO:0009409 GO:0051412 GO:0034097 GO:0042493 GO:0009629 GO:0035902 GO:0009416 GO:0032496 GO:0035994 GO:0032570 GO:0009636 GO:0035914 GO:0030431 GO:0060395 GO:0007179
InterPro	IPR000837 IPR004827 IPR029816
PANTHER	PTHR23351 PTHR23351:SF4
Pfam	PF00170
PRINTS	PR00042
SMART	SM00338
PROSITE	PS50217 PS00036

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005783	endoplasmic reticulum	PMID:26475860^[1]	ECO:0000314			C		Figure 6a, d and f	complete CACAO 11044
	GO:0005634	nucleus	PMID:26475860^[1]	ECO:0000314			C		Figure 5a	complete CACAO 11045
	GO:0005737	cytoplasm	PMID:26475860^[1]	ECO:0000314			C		Figure 5 a	complete CACAO 11046
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:11925568^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:11925568^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:11925568^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:11925568^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0001297 MGI:MGI:102858 MGI:MGI:109384 MGI:MGI:1859147 MGI:MGI:1932093 MGI:MGI:95574 PANTHER:PTN001156258 RGD:1308198 RGD:2626 RGD:2627 RGD:2628 UniProtKB:P01100 UniProtKB:P18847 UniProtKB:P53539 WB:WBGene00001345	C		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109384 MGI:MGI:1859147 MGI:MGI:1932093 MGI:MGI:95574 MGI:MGI:95575 PANTHER:PTN001156258 RGD:2627 UniProtKB:P15407 UniProtKB:Q9NR55	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901216	positive regulation of neuron death	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071277	cellular response to calcium ion	PMID:19365557^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(EMAPA:17528) occurs_in:(CL:0000312)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071276	cellular response to cadmium ion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	P		Seeded From UniProt	complete
enables	GO:0070412	R-SMAD binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060395	SMAD protein signal transduction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	P		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:9294610^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	regulates_o_occurs_in:(CL:0000057) has_regulation_target:(MGI:MGI:107179)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045672	positive regulation of osteoclast differentiation	PMID:23395171^[6]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_results_in_acquisition_of_features_of:(CL:0002092)	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	F		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042493	response to drug	PMID:9098922^[7]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(EMAPA:16039)\|occurs_in:(EMAPA:16039)\|occurs_in:(EMAPA:16039)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035994	response to muscle stretch	PMID:20442316^[8]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(EMAPA:17701)	Seeded From UniProt	complete
part_of	GO:0035976	transcription factor AP-1 complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035914	skeletal muscle cell differentiation	PMID:22147266^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034614	cellular response to reactive oxygen species	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	P		Seeded From UniProt	complete
part_of	GO:0032993	protein-DNA complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031668	cellular response to extracellular stimulus	PMID:9294610^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000057) has_input:(MGI:MGI:107179)	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010468	regulation of gene expression	PMID:22284419^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007399	nervous system development	PMID:11925568^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387304	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007179	transforming growth factor beta receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006366	transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006355	regulation of transcription, DNA-templated	PMID:11925568^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387304	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006355	regulation of transcription, DNA-templated	PMID:12220541^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:12943993^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:7595148^[13]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35142)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11747369^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11925568^[2]	ECO:0000305	curator inference used in manual assertion	GO:0003700	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19033670^[15]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P12841	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P12841	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:11925568^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387304	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:12220541^[11]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	F		Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	PMID:20442316^[8]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_in:(EMAPA:17701) has_direct_input:(MGI:MGI:1861447)	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:12486129^[16]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2626	F		Seeded From UniProt	complete
enables	GO:0001102	RNA polymerase II activating transcription factor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
enables	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P01100	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:23980096^[17]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0071276	cellular response to cadmium ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	P		Seeded From UniProt	complete
enables	GO:0070412	R-SMAD binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
involved_in	GO:0060395	SMAD protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	P		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	P		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
part_of	GO:0035976	transcription factor AP-1 complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	C		Seeded From UniProt	complete
involved_in	GO:0034614	cellular response to reactive oxygen species	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	P		Seeded From UniProt	complete
part_of	GO:0032993	protein-DNA complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	C		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
involved_in	GO:0007179	transforming growth factor beta receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
enables	GO:0001102	RNA polymerase II activating transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
enables	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P01100 ensembl:ENSP00000306245	F		Seeded From UniProt	complete
involved_in	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:1901216	positive regulation of neuron death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0051591	response to cAMP	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0051412	response to corticosterone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	F		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	C		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0035902	response to immobilization stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0034097	response to cytokine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0032870	cellular response to hormone stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0032570	response to progesterone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0032496	response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0030431	sleep	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	C		Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0009636	response to toxic substance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0009629	response to gravity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0009612	response to mechanical stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0009416	response to light stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0009409	response to cold	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	F		Seeded From UniProt	complete
involved_in	GO:0007568	aging	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0007565	female pregnancy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
involved_in	GO:0006366	transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	F		Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	F		Seeded From UniProt	complete
involved_in	GO:0001661	conditioned taste aversion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12841 ensembl:ENSRNOP00000010712	P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6FG41 ensembl:ENSP00000306245	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000837 InterPro:IPR029816	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000837 InterPro:IPR004827	F		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR029816	C		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004827	P		Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000837 InterPro:IPR029816	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256 UniProtKB-SubCell:SL-0095	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0091	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Cardozo Gizzi, AM et al. (2015) The Catalytic Efficiency of Lipin 1β Increases by Physically Interacting with the Proto-oncoprotein c-Fos. J. Biol. Chem. 290 29578-92 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 Zhang, J et al. (2002) c-fos regulates neuronal excitability and survival. Nat. Genet. 30 416-20 PubMed GONUTS page
↑ ^3.0 ^3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Villaescusa, JC et al. (2009) Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation. PLoS ONE 4 e5213 PubMed GONUTS page
↑ ^5.0 ^5.1 Schreiber, M et al. (1997) Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis). Oncogene 15 1171-8 PubMed GONUTS page
↑ Kim, H et al. (2013) Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation. Cell Metab. 17 249-60 PubMed GONUTS page
↑ Wlodarczyk, BC et al. (1996) Valproic acid-induced changes in gene expression during neurulation in a mouse model. Teratology 54 284-97 PubMed GONUTS page
↑ ^8.0 ^8.1 Mohamed, JS et al. (2010) Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch. FASEB J. 24 3330-40 PubMed GONUTS page
↑ Rajan, S et al. (2012) Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation. Physiol. Genomics 44 183-97 PubMed GONUTS page
↑ Gall, A et al. (2012) Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36 120-31 PubMed GONUTS page
↑ ^11.0 ^11.1 Gong, P et al. (2002) Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite. Arch. Biochem. Biophys. 405 265-74 PubMed GONUTS page
↑ Ellsworth, BS et al. (2003) The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein. Mol. Cell. Endocrinol. 206 93-111 PubMed GONUTS page
↑ Dickson, SL et al. (1995) GH-deficient dw/dw rats and lit/lit mice show increased Fos expression in the hypothalamic arcuate nucleus following systemic injection of GH-releasing peptide-6. J. Endocrinol. 146 519-26 PubMed GONUTS page
↑ Wahlin, KJ et al. (2001) Neurotrophic signaling in normal and degenerating rodent retinas. Exp. Eye Res. 73 693-701 PubMed GONUTS page
↑ Takayanagi, Y et al. (2008) Endogenous prolactin-releasing peptide regulates food intake in rodents. J. Clin. Invest. 118 4014-24 PubMed GONUTS page
↑ Meech, R et al. (2003) The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors. J. Biol. Chem. 278 8269-78 PubMed GONUTS page
↑ Maruyama, K et al. (2013) Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP. J. Exp. Med. 210 1947-60 PubMed GONUTS page

[PMID:26475860-1] 1.0 ^1.1 ^1.2 Cardozo Gizzi, AM et al. (2015) The Catalytic Efficiency of Lipin 1β Increases by Physically Interacting with the Proto-oncoprotein c-Fos. J. Biol. Chem. 290 29578-92 PubMed GONUTS page

[PMID:11925568-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 Zhang, J et al. (2002) c-fos regulates neuronal excitability and survival. Nat. Genet. 30 416-20 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19365557-4] Villaescusa, JC et al. (2009) Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation. PLoS ONE 4 e5213 PubMed GONUTS page

[PMID:9294610-5] 5.0 ^5.1 Schreiber, M et al. (1997) Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis). Oncogene 15 1171-8 PubMed GONUTS page

[PMID:23395171-6] Kim, H et al. (2013) Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation. Cell Metab. 17 249-60 PubMed GONUTS page

[PMID:9098922-7] Wlodarczyk, BC et al. (1996) Valproic acid-induced changes in gene expression during neurulation in a mouse model. Teratology 54 284-97 PubMed GONUTS page

[PMID:20442316-8] 8.0 ^8.1 Mohamed, JS et al. (2010) Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch. FASEB J. 24 3330-40 PubMed GONUTS page

[PMID:22147266-9] Rajan, S et al. (2012) Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation. Physiol. Genomics 44 183-97 PubMed GONUTS page

[PMID:22284419-10] Gall, A et al. (2012) Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease. Immunity 36 120-31 PubMed GONUTS page

[PMID:12220541-11] 11.0 ^11.1 Gong, P et al. (2002) Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite. Arch. Biochem. Biophys. 405 265-74 PubMed GONUTS page

[PMID:12943993-12] Ellsworth, BS et al. (2003) The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein. Mol. Cell. Endocrinol. 206 93-111 PubMed GONUTS page

[PMID:7595148-13] Dickson, SL et al. (1995) GH-deficient dw/dw rats and lit/lit mice show increased Fos expression in the hypothalamic arcuate nucleus following systemic injection of GH-releasing peptide-6. J. Endocrinol. 146 519-26 PubMed GONUTS page

[PMID:11747369-14] Wahlin, KJ et al. (2001) Neurotrophic signaling in normal and degenerating rodent retinas. Exp. Eye Res. 73 693-701 PubMed GONUTS page

[PMID:19033670-15] Takayanagi, Y et al. (2008) Endogenous prolactin-releasing peptide regulates food intake in rodents. J. Clin. Invest. 118 4014-24 PubMed GONUTS page

[PMID:12486129-16] Meech, R et al. (2003) The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors. J. Biol. Chem. 278 8269-78 PubMed GONUTS page

[PMID:23980096-17] Maruyama, K et al. (2013) Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP. J. Exp. Med. 210 1947-60 PubMed GONUTS page

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