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Category:GO:0035976 ! transcription factor AP-1 complex
name: transcription factor AP-1 complex
namespace: cellular_component
def: "A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes." [GOC:bf, GOC:BHF, GOC:rl, PMID:20060892, PMID:9069263, Wikipedia:AP-1_transcription_factor]
synonym: "Activating protein 1 complex" EXACT [GOC:rl]
synonym: "AP-1 complex" EXACT [GOC:rl]
synonym: "AP1 complex" EXACT [GOC:rl]
synonym: "transcription factor AP1 complex" EXACT [GOC:rl]
is_a: GO:0090575 ! RNA polymerase II transcription regulator complex
AmiGO
<GOterm>GO:0035976</GOterm>
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